WormMine

WS295

Intermine data mining platform for C. elegans and related nematodes

Gene :

WormBase Gene ID  ? WBGene00234137 Gene Name  Bma-pyp-1
Sequence Name  ? Bm13876 Organism  Brugia malayi
Automated Description  Predicted to enable inorganic diphosphate phosphatase activity and magnesium ion binding activity. Predicted to be involved in phosphate-containing compound metabolic process. Predicted to be located in cytoplasm. Is an ortholog of C. elegans pyp-1. In C. elegans, pyp-1 is involved in innate immune response. Biotype  SO:0001217
Genetic Position 
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1 Organism

Name Taxon Id
Brugia malayi 6279

0 Synonyms

Genomics

1 Transcripts

WormMine ID Sequence Name Length (nt) Chromosome Location
Transcript:Bm13876.1 Bm13876.1   [unknown]
 

Other

1 CDSs

WormMine ID Sequence Name Length (nt) Chromosome Location
CDS:Bm13876 Bm13876   [unknown]

0 RNAi Result

0 Allele

0 Chromosome

0 Chromosome Location

2 Data Sets

Name URL
WormBaseAcedbConverter  
GO Annotation data set  

0 Downstream Intergenic Region

6 Expression Clusters

Regulated By Treatment Description Algorithm Primary Identifier
  Transcripts that showed significantly lower expression in adult comparing to in microfilariae. edgeR v3.28. FDR < 0.05, fold change > 2. WBPaper00061765:Adult_vs_Micro_Downregulated
  Transcripts that showed significantly increased expression in male B. malayi 120 days after infecting gerbils, comparing to 30 days after infecting gerbils. EdgeR(v3.16.5), FDR < 0.05. WBPaper00051007:upregulated_M120_vs_M30
  Transcripts that showed significantly increased expression in female B. malayi 120 days after infecting gerbils, comparing to 30 days after infecting gerbils. EdgeR(v3.16.5), FDR < 0.05. WBPaper00051007:upregulated_F120_vs_F30
  Transcripts that showed significantly lower expression in L4 larva comparing to in microfilariae. edgeR v3.28. FDR < 0.05, fold change > 2. WBPaper00061765:L4_vs_Micro_Downregulated
  Proteins that showed significantly increased expression in parasites exposed to 20-hydroxyecdysone. An empirical filter of proteins with more than two peptides identified, a P value <0.05 and a greater than two-fold change of differential expression, was applied to the data. The Bonferroni correction was applied to correct the P value for the proteins analyzed. WBPaper00049261:20-hydroxyecdysone_upregulated_protein
  Time-course transcript abundance profiles. P116, k-means clusters of Brugia malayi during development in Aedes aegypti LVP between day 1 and 8 post infection; H114, k-means clusters of Ae. aegypti LVP infected with B. malayi between day 0 and 8 post infection; and HR14, host response profile comparing infected vs. uninfected A. aegypti LVP. Non-flat profiles (p < 0.01 and maximum fold-difference among time points > 2) were grouped into common temporal patterns using k-means clustering. WBPaper00045439:BM_Cluster_P5

0 Expression Patterns

4 GO Annotation

Annotation Extension Qualifier
  enables
  enables
  involved_in
  located_in

0 Homologues

0 Locations

4 Ontology Annotations

Annotation Extension Qualifier
  enables
  enables
  involved_in
  located_in

0 Regulates Expr Cluster

0 Sequence

1 Sequence Ontology Term

Identifier Name Description
gene  

0 Strains

0 Upstream Intergenic Region