WormMine: DiseaseOntology DOID:0080164 myeloid and lymphoid neoplasms with eosinophilia and abnormalities of PDGFRA, PDGFRB, and FGFR1 Disease Ontology

• Namespace: disease_ontology
• Obsolete: false
• Description: A myeloid neoplasm that is characterized by the formation of abnormal fusion genes that encode constitutively activated tyrosine kinases.

1 Ontology

• Name: Disease Ontology

11 Parents

Identifier	Name	Description
DOID:0050686	organ system cancer	A cancer that is classified based on the organ it starts in.
DOID:162	cancer	A disease of cellular proliferation that is malignant and primary, characterized by uncontrolled cellular proliferation, local cell invasion and metastasis.
DOID:7	disease of anatomical entity	A disease that manifests in a defined anatomical structure.
DOID:14566	disease of cellular proliferation	A disease that is characterized by abnormally rapid cell division.
DOID:4	disease	A disease is a disposition (i) to undergo pathological processes that (ii) exists in an organism because of one or more disorders in that organism.
DOID:4960	bone marrow cancer	A hematopoietic cancer that derives_from the blood-forming stem cells of the bone marrow.
DOID:0070004	myeloid neoplasm	A bone marrow cancer that is formed of any one of the bone marrow cells belonging to the granulocytic (neutrophil, eosinophil, basophil), monocytic/macrophage, erythroid, megakaryocytic and mast cell lineages.
DOID:4961	bone marrow disease	A hematopoietic system disease that is located_in the bone marrow.
DOID:74	hematopoietic system disease	A disease of anatomical entity that has_material_basis_in hematopoietic cells.
DOID:2531	hematologic cancer	An organ system cancer located in the hematological system that is characterized by uncontrolled cellular proliferation in blood, bone marrow and lymph nodes.
DOID:0080164	myeloid and lymphoid neoplasms with eosinophilia and abnormalities of PDGFRA, PDGFRB, and FGFR1	A myeloid neoplasm that is characterized by the formation of abnormal fusion genes that encode constitutively activated tyrosine kinases.

13 Relations

Relationship	Parent Term . Identifier	Child Term . Identifier
is_a	DOID:0070004	DOID:0080164
is_a	DOID:4	DOID:0080164
is_a	DOID:0050686	DOID:0080164
is_a	DOID:4960	DOID:0080164
is_a	DOID:4961	DOID:0080164
is_a	DOID:7	DOID:0080164
is_a	DOID:2531	DOID:0080164
is_a	DOID:162	DOID:0080164
is_a	DOID:74	DOID:0080164
is_a	DOID:14566	DOID:0080164
is_a	DOID:0080164	DOID:0080165
is_a	DOID:0080164	DOID:0080166
is_a	DOID:0080164	DOID:0080167

2 Synonyms

• Name: Myeloid and lymphoid neoplasms with eosinophilia and abnormalities of platelet-derived growth factor receptor alpha (PDGFRA), platelet-derived growth factor receptor beta (PDGFRB), and fibroblast growth factor receptor-1 (FGFR1) are a group of hematologic neoplasms
• Type: synonym

• Name: Myeloid and Lymphoid Neoplasms with Eosinophilia and Rearrangement of PDGFRA, PDGFRB, or FGFR1, or with PCM1-JAK2
• Type: synonym