WormMine: Gene WBGene00045082

• WormBase Gene ID: WBGene00045082
• Gene Name: F46F11.12
• Sequence Name: F46F11.12
• Organism: Caenorhabditis elegans
• Automated Description: Is affected by several genes including hpl-2; dlc-1; and ilc-17.1 based on tiling array and RNA-seq studies. Is affected by Tunicamycin based on RNA-seq studies.
• Biotype: SO:0001267
• Genetic Position: :±
• Length (nt): 155

1 Organism

• Name: Caenorhabditis elegans
• Taxon Id: 6239

1 Synonyms

• Value: WBGene00045082

Genomics

1 Transcripts

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
Transcript:F46F11.12	F46F11.12	155	I: 5611663-5611817

Other

0 CDSs

2 RNAi Result

• WBRNAi00032369
• WBRNAi00000649

2 Allele

• gk962706
• gk963902

1 Chromosome

• WormBase ID: I
• Organism: Caenorhabditis elegans
• Length (nt): 15072434

1 Chromosome Location

• Feature . Primary Identifier: WBGene00045082
• Start: 5611663
• End: 5611817
• Strand: -1

2 Data Sets

• WormBaseAcedbConverter
• C. elegans genomic annotations (GFF3 Gene)

0 Downstream Intergenic Region

12 Expression Clusters

Regulated By Treatment	Description	Algorithm	Primary Identifier
Osmotic stress	Transcripts that showed significantly altered expression with 500 mM salt (NaCl) vs 100 mM salt when food was present	DESeq(version 1.10.1), FDR < 0.05.	WBPaper00050726:OsmoticStress_regulated_Food
	Transcripts depleted in purified oocyte P bodies comparing to in whole oocytes.	DESeq2, FDR < 0.05, fold change > 2.	WBPaper00065975:P-body_vs_oocyte_depleted
	Transcripts depleted in purified oocyte P bodies comparing to in the whole animal.	DESeq2, FDR < 0.05, fold change > 2.	WBPaper00065975:P-body_vs_WholeAnimal_depleted
	Transcripts that showed significantly decreased expression in hpl-2(tm1489) comparing to in N2 animals.	DESeq2, adjusted p-value < 0.05, log2 fold change > 2 or < -2.	WBPaper00054493:hpl-2(tm1489)_downregulated
	Transcripts that showed significantly increased expression in ilc-17.1(syb5296) comparing to in N2 animals at L4 larva stage.	DESeq2, fold change > 2, FDR < 0.05.	WBPaper00066594:ilc-17.1(syb5296)_upregulated
	Transcripts that interact with 3xFLAG-DLC-1 as identified by immunoprecipitation followed by RNA sequencing.	DESeq2, fold change > 2,, p-value < 0.01	WBPaper00055334:DLC-1_interacting
	Potental DAF-12 target genes identified by ChIP-chip analysis performed on strain ALF4 [daf-12	Affymetrix TAS software that computed for each probe estimates of fold enrichment (in linear scale) over hybridization with input DNA. At the same time, TAS calculated for each probe a p-value by applying a Wilcoxon signed rank test. A threshold of 2.5 was selected, which corresponds to probe intensities approximately 2.5 times stronger on the ChIP array than on the Input array. Additional TAS threshold parameters were MinRun=180 bp, MaxGap=300 bp. TAS analysis showed that the selected threshold of 2.5 corresponds approximately to a p-value of 0.01.	WBPaper00040221:DAF-12_target_ALF4
	Transcripts that showed significantly increased expression in nfki-1(cer1) animals at L4 larva stage, comparing to in N2 animals.	Differentially expressed genes between wild type and knockouts were explored using DESeq2 R package (v.1.20.0) considering a threshold of adjusted p value < 0.01.	WBPaper00060445:nfki-1(cer1)_upregulated_L4
	Transcripts that showed significantly decreased expression in lin-52(n771) comparing to in N2 animals at L1 larva stage.	DESeq2	WBPaper00065149:lin-52(n771)_downregulated
	ncRNAs with significantly decreased expression in cep-1(gk138) than in N2 after UV irradiation, according to RNAseq.	ncRNAs with more than 2 fold difference in expression are considered differentially expressed	WBPaper00045380:cep-1(gk138)_downregulated_UV
	ncRNAs with significantly increased expression in cep-1(gk138) than in N2 under normal conditions, according to RNAseq.	ncRNAs with more than 2 fold difference in expression are considered differentially expressed	WBPaper00045380:cep-1(gk138)_upregulated_normal
	Transcripts that showed significantly increased expression after 4 hours of treatment by 50 ub per ml tunicamycin at L4 larva stage, in RtcB(null) animals.	Fold change > 1.75	WBPaper00045971:tunicamycin_upregulated_RtcB(null)

0 Expression Patterns

0 GO Annotation

0 Homologues

1 Locations

• Feature . Primary Identifier: WBGene00045082
• Start: 5611663
• End: 5611817
• Strand: -1

0 Ontology Annotations

0 Regulates Expr Cluster

1 Sequence

• Length: 155

1 Sequence Ontology Term