WormMine

WS295

Intermine data mining platform for C. elegans and related nematodes

Gene :

WormBase Gene ID  ? WBGene00269373 Gene Name  M01D1.12
Sequence Name  ? M01D1.12 Organism  Caenorhabditis elegans
Automated Description  Enriched in several structures, including ABalaaaala; ABalaapaaa; ABalaappppa; AUA; and ciliated neurons based on single-cell RNA-seq studies. Is affected by several genes including etr-1; ash-2; and hsf-1 based on RNA-seq studies. Is affected by stearic acid; sucrose; and Camptothecin based on RNA-seq studies. Is predicted to encode a protein with the following domains: F-box associated; Zygotic Embryogenesis-Associated Protein; and F-box associated domain, type 2. Biotype  SO:0001217
Genetic Position  Length (nt)  ? 756
Quick Links:
 
Quick Links:
 

1 Organism

Name Taxon Id
Caenorhabditis elegans 6239

1 Synonyms

Value
WBGene00269373

Genomics

1 Transcripts

WormMine ID Sequence Name Length (nt) Chromosome Location
Transcript:M01D1.12.1 M01D1.12.1 756   II: 1026970-1027725
 

Other

1 CDSs

WormMine ID Sequence Name Length (nt) Chromosome Location
CDS:M01D1.12 M01D1.12 756   II: 1026970-1027725

3 RNAi Result

WormBase ID
WBRNAi00034343
WBRNAi00049730
WBRNAi00017092

34 Allele

Public Name
gk964317
gk963801
WBVar02124869
WBVar02124319
WBVar02122521
WBVar02121534
gk962873
gk962648
gk964443
WBVar02124386
WBVar01360111
WBVar01360122
WBVar01435726
WBVar01435725
WBVar01435724
gk132856
WBVar00037286
WBVar02122089
WBVar00544412
WBVar01533250
gk432314
gk791564
gk626914
gk685445
gk676431
gk914079
WBVar00164003
WBVar02120597
gk898548
gk617078

1 Chromosome

WormBase ID Organism Length (nt)
II Caenorhabditis elegans 15279421  

1 Chromosome Location


Feature . Primary Identifier
Start End Strand
WBGene00269373 1026970 1027725 1

2 Data Sets

Name URL
WormBaseAcedbConverter  
C. elegans genomic annotations (GFF3 Gene)  

0 Downstream Intergenic Region

51 Expression Clusters

Regulated By Treatment Description Algorithm Primary Identifier
  Transcripts that showed significantly increased expression in L1 neural cells comparing to in adult neural cells. DESeq2 (v1.18.1) fold change > 2, P-adj<0.05, using BenjaminiHochberg correction. WBPaper00060811:L1_vs_adult_upregulated_neural
  Transcripts of coding genes that showed significantly decreased expression in muscle. DESeq2 (version 1.24.0). Transcripts with a false-discovery rate adjusted p-value less than 0.05 were considered significantly differentially expressed. WBPaper00062325:muscle_depleted_coding-RNA
  Transcripts that showed significantly increased expression in sin-3(tm1276) comparing to in N2. DESeq2, fold change > 2, p-value < 0.01. WBPaper00061203:sin-3(tm1276)_upregulated
  Top 300 transcripts enriched in ABalppppppa, ABpraaapppa according to single cell RNAseq. Top 300 enriched transcripts were determined by log2.ratio of the tpm in the cell type vs the tpm in the other cells * the log2 of the cell.type tpm. WBPaper00061340:ASE_parent
  Transcripts that showed significantly decreased expression in sin-3(tm1276) comparing to in N2 at early embryo when there were only 3 -5 eggs in the adult. DESeq2, fold change > 2, adjusted p-value < 0.01 WBPaper00058598:sin-3(tm1276)_downregulated
  Transcripts that showed significantly increased expression among animals treated with 400mM sucrose and 500 mg per ml stearic acid from L1 to L4 larva stage comparing to animals grown up on control plates. CuffDiff, FDR <= 0.05, fold change >= 2. WBPaper00059253:sucrose_stearic-acid_upregulated
  Transcripts that showed significantly increased expression in hda-2(ok1479) comparing to in N2 animals. DESeq2 (version 1.28.1), FDR < 0.01, fold change > 2. WBPaper00062159:hda-2(ok1479)_upregulated
Bacteria infection: Enterococcus faecalis OG1RF. 16 hours of exposure after L4 larva stage at 25C. Transcripts that showed significantly increased expression in skpo-1(ok1640) animals fed by E. faecalis strain OG1RF for 16 hours after L4 larva stage at 25C. DESeq2, fold change > 2. WBPaper00061081:E.faecalis_upregulated_skpo-1(ok1640)
  Germline-enriched and sex-biased expression profile cluster A. hierarchical clustering [cgc6390]:Cluster_A
  Top 300 transcripts enriched in ABalppppapa, ABpraaapapa according to single cell RNAseq. Top 300 enriched transcripts were determined by log2.ratio of the tpm in the cell type vs the tpm in the other cells * the log2 of the cell.type tpm. WBPaper00061340:OLL_parent
  Transcripts that showed significantly increased expression in lin-29(n333) comparing to in N2 at day 1 adult stage. DESeq2, FDR < 0.01, fold change > 2. WBPaper00066970:lin-29(n333)_upregulated
  Transcripts that showed significantly increased expression in endu-2(tm4977) comparing to in N2 animals at young adult stage. The DESeq2 (GalaxyVersion 2.11.40.6 + galaxy1) was used to determine differentiallyexpressed features from count tables of differential transcript abundances. log2FC > 1, FDR < 0.01. WBPaper00065749:endu-2(tm4977)_upregulated
  Top 300 transcripts enriched in ABplapppaa, ABprapppaa according to single cell RNAseq. Top 300 enriched transcripts were determined by log2.ratio of the tpm in the cell type vs the tpm in the other cells * the log2 of the cell.type tpm. WBPaper00061340:PVQ_parent
  Genome-wide analysis of developmental and sex-regulated gene expression profile. self-organizing map cgc4489_group_9
  Transcripts that showed significantly increased expression by somatic RAGA-1 degradation. DESeq2_1.34.0, FDR < 0.01, fold change > 2. WBPaper00066005:RAGA-1_degradation_somatic_upregulated
  Transcripts that showed significantly decreased expression in hda-1(RNAi) embryos comparing to control animals. DESeq2, fold change > 2, FDR < 0.05. WBPaper00067044:hda-1(RNAi)_downregulated
  Transcripts that showed significantly decreased expression in hsf-1(RNAi) comparing to in ash-2 animals injected with vector. Differential mRNA expression using DESeq2. mRNAs with a FDR < 0.05 and fold change > 2 considered differentially expressed. WBPaper00066232:hsf-1(RNAi)_downregulated_ash-2
  Transcripts that showed significantly decreased expression in hsf-1(RNAi) comparing to in wild type animals injected with vector. Differential mRNA expression using DESeq2. mRNAs with a FDR < 0.05 and fold change > 2 considered differentially expressed. WBPaper00066232:hsf-1(RNAi)_downregulated_WT
  Transcripts that showed significantly decreased expression in animals exposed to Camptothecin for 3 hours at 2C. p < 0.01, logFC > 1 or p < 0.01, logFC < -1. WBPaper00066610:Camptothecin_downregulated_2C_3h
  Transcripts that showed significantly decreased expression in him-17(me24) comparing to in N2 animals. DESeq2, fold change > 2, FDR < 0.05. WBPaper00064769:him-17(me24)_downregulated
  Top 300 transcripts enriched in ADFL, ADFR, AWBL, AWBR according to single cell RNAseq. Top 300 enriched transcripts were determined by log2.ratio of the tpm in the cell type vs the tpm in the other cells * the log2 of the cell.type tpm. WBPaper00061340:ADF_AWB
  Top 300 transcripts enriched in ASGL, ASGR, AWAL, AWAR according to single cell RNAseq. Top 300 enriched transcripts were determined by log2.ratio of the tpm in the cell type vs the tpm in the other cells * the log2 of the cell.type tpm. WBPaper00061340:ASG_AWA
  Top 300 transcripts enriched in AUAL, AUAR according to single cell RNAseq. Top 300 enriched transcripts were determined by log2.ratio of the tpm in the cell type vs the tpm in the other cells * the log2 of the cell.type tpm. WBPaper00061340:AUA
  Top 300 transcripts enriched in ABaraapapaa, ABaraapppaa according to single cell RNAseq. Top 300 enriched transcripts were determined by log2.ratio of the tpm in the cell type vs the tpm in the other cells * the log2 of the cell.type tpm. WBPaper00061340:NSM_parent
Glucose rich diet. Transcripts that showed significantly increased expression in lpin-1(RNAi) animals grown on plates with additional 2% high glucose, comparing to lpin-1(RNAi) animals without additional glucose. Differentially expressed genes (fold change > 2 and adjusted p value < 0.05) were identified by using DESeq2 (v.1.22.2). WBPaper00059735:glucose_upregulated_lpin-1(RNAi)
Glucose rich diet. Transcripts that showed significantly increased expression in WT animals (N2 injected with empty RNAi vector) grown on plates with additional 2% high glucose, comparing to WT animals without additional glucose. Differentially expressed genes (fold change > 2 and adjusted p value < 0.05) were identified by using DESeq2 (v.1.22.2). WBPaper00059735:glucose_upregulated_N2
  Top 300 transcripts enriched in ABalpappaa, ABarapapaa according to single cell RNAseq. Top 300 enriched transcripts were determined by log2.ratio of the tpm in the cell type vs the tpm in the other cells * the log2 of the cell.type tpm. WBPaper00061340:I2_grandparent
  Top 300 transcripts enriched in ABplppaapa, ABprppaapa according to single cell RNAseq. Top 300 enriched transcripts were determined by log2.ratio of the tpm in the cell type vs the tpm in the other cells * the log2 of the cell.type tpm. WBPaper00061340:RIM_parent
  Top 300 transcripts enriched in ABalppppaa, ABpraaapaa according to single cell RNAseq. Top 300 enriched transcripts were determined by log2.ratio of the tpm in the cell type vs the tpm in the other cells * the log2 of the cell.type tpm. WBPaper00061340:ADL_parent
  Top 300 transcripts enriched in ABalaaaala, ABalaapaaa according to single cell RNAseq. Top 300 enriched transcripts were determined by log2.ratio of the tpm in the cell type vs the tpm in the other cells * the log2 of the cell.type tpm. WBPaper00061340:AIN_parent

2 Expression Patterns

Remark Reporter Gene Primary Identifier Pattern Subcellular Localization
    Expr2023341 Single cell embryonic expression. Only cell types with an expression fraction of greater 0.2 of the maximum expressed fraction are labeled (Full data can be downloaded from http://caltech.wormbase.org/pub/wormbase/datasets-published/packer2019/). The colors represent the broad cell class to which the cell type has been assigned. The size of the point is proportional to the log2 of the numbers of cells in the dataset of that cell type. Interactive visualizations are available as a web app (https://cello.shinyapps.io/celegans/) and can also be installed as an R package (https://github.com/qinzhu/VisCello.celegans).  
    Expr2005120 Single cell embryonic expression. Only cell types with an expression fraction of greater 0.2 of the maximum expressed fraction are labeled (Full data can be downloaded from http://caltech.wormbase.org/pub/wormbase/datasets-published/packer2019/). The colors represent the broad cell class to which the cell type has been assigned. The size of the point is proportional to the log2 of the numbers of cells in the dataset of that cell type. Interactive visualizations are available as a web app (https://cello.shinyapps.io/celegans/) and can also be installed as an R package (https://github.com/qinzhu/VisCello.celegans).  

0 GO Annotation

0 Homologues

1 Locations


Feature . Primary Identifier
Start End Strand
WBGene00269373 1026970 1027725 1

0 Ontology Annotations

0 Regulates Expr Cluster

1 Sequence

Length
756

1 Sequence Ontology Term