WormMine

WS295

Intermine data mining platform for C. elegans and related nematodes

Gene :

WormBase Gene ID  ? WBGene00044370 Gene Name  C41H7.9
Sequence Name  ? C41H7.9 Organism  Caenorhabditis elegans
Automated Description  Enriched in AFD and intestine based on RNA-seq studies. Is affected by several genes including etr-1; drh-3; and clk-1 based on RNA-seq and microarray studies. Is affected by six chemicals including hydrogen sulfide; rifampin; and allantoin based on microarray and RNA-seq studies. Biotype  SO:0001217
Genetic Position  Length (nt)  ? 153
Quick Links:
 
Quick Links:
 

1 Organism

Name Taxon Id
Caenorhabditis elegans 6239

1 Synonyms

Value
WBGene00044370

Genomics

1 Transcripts

WormMine ID Sequence Name Length (nt) Chromosome Location
Transcript:C41H7.9.1 C41H7.9.1 153   II: 3012081-3012233
 

Other

1 CDSs

WormMine ID Sequence Name Length (nt) Chromosome Location
CDS:C41H7.9 C41H7.9 153   II: 3012081-3012233

3 RNAi Result

WormBase ID
WBRNAi00042324
WBRNAi00011852
WBRNAi00117899

13 Allele

Public Name
gk964317
gk963801
gk962754
gk963671
gk964487
gk964488
WBVar01691974
WBVar01719085
WBVar01719084
gk137424
WBVar01835416
WBVar02092115
gk938444

1 Chromosome

WormBase ID Organism Length (nt)
II Caenorhabditis elegans 15279421  

1 Chromosome Location


Feature . Primary Identifier
Start End Strand
WBGene00044370 3012081 3012233 -1

2 Data Sets

Name URL
WormBaseAcedbConverter  
C. elegans genomic annotations (GFF3 Gene)  

1 Downstream Intergenic Region

WormBase ID Name Sequence Name Length (nt) Chromosome Location Organism
intergenic_region_chrII_3009949..3012080   2132 II: 3009949-3012080 Caenorhabditis elegans

18 Expression Clusters

Regulated By Treatment Description Algorithm Primary Identifier
Osmotic stress Transcripts that showed significantly altered expression with 500 mM salt (NaCl) vs 100 mM salt when no food was present DESeq(version 1.10.1), FDR < 0.05. WBPaper00050726:OsmoticStress_regulated_NoFood
  Transcripts expressed in intestine, according to PAT-Seq analysis using Pges-1-GFP-3XFLAG mRNA tagging. Cufflinks FPKM value >=1. WBPaper00050990:intestine_expressed
  Transcripts expressed in vulva. FPKM >= 1. WBPaper00064122:vulva_transcriptome
  Transcripts that showed significantly decreased expression in daf-16(mgDf50) comparing to in N2 at L1 larva stage. DESeq v1.20.0 was used to analyze differential gene expression. Transcripts with adjusted p-value < 0.05 were considered differentialled expressed. WBPaper00048971:daf-16(mgDf50)_downregulated_L1
  Transcripts detected in body muscle nuclei according to a nuclear FACS-based strategy. Cufflinks WBPaper00065120:body-muscle-transcriptome
  Transcripts that showed significantly decreased expression in nhl-2(ok818) comparing to in N2 at 25C. EdgeR, FDR < 0.05, fold change < 0.5. WBPaper00055971:nhl-2(ok818)_25C_upregulated
  Transcripts that showed significantly increased expression in animals lacking P granules by RNAi experiments targeting pgl-1, pgl-3, glh-1 and glh-4, and unc-119-GFP(+), comparing to in control animals, at 2-day post L4 adult hermaphrodite stage. DESeq2, Benjamini-Hochberg multiple hypothesis corrected p-value < 0.05 and fold change > 2. WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
  Transcripts of coding genes that showed significantly increased expression in muscle. DESeq2 (version 1.24.0). Transcripts with a false-discovery rate adjusted p-value less than 0.05 were considered significantly differentially expressed. WBPaper00062325:muscle_enriched_coding-RNA
  Transcripts unqiuely expressed in intestine, according to PAT-Seq analysis using Pges-1-GFP-3XFLAG mRNA tagging. Cufflinks FPKM value >=1. WBPaper00050990:intestine_enriched
  Transcripts that showed significantly increased expression in animals fed with JM103 bacteria producing Cry5B, comparing to control animals fed with JM103. ANOVA, p-value < 0.05. WBPaper00056167:Cry5B_upregulated
  Transcripts that showed significantly decreased expression after animals were treated with 100uM Rapamycin, 50uM Rifampicin and 250uM Allantoin from day 1 to day 3 adult hermaphradite. DESeq2(v1.14.1), fold change > 2, p-value < 0.05 WBPaper00055354:Rapamycin-Rifampicin-Allantoin_downregulated
  Transcripts that showed significantly decreased expression after animals were treated with 50uM Rifampicin and 100uM Psora from day 1 to day 3 adult hermaphradite. DESeq2(v1.14.1), fold change > 2, p-value < 0.05 WBPaper00055354:Rifampicin-Psora_downregulated
  Down-regulated genes (fold change > 1.5) in two CoQ-deficient clk-1 mutant strains (e2519, qm30) compared to wild types N2. Fold-changes of intensities were calculated from the arithmetic mean of gene expression values between experimental and corresponding control group. Fold change >= 1.5 was used as cut-off. WBPaper00045774:clk-1_downregulated
  Transcripts that showed significantly decreased expression after animals were treated with 100uM Rapamycin, 50uM Rifampicin and 100uM Psora from day 1 to day 3 adult hermaphradite. DESeq2(v1.14.1), fold change > 2, p-value < 0.05 WBPaper00055354:Rapamycin-Rifampicin-Psora_downregulated
  Genes that are significantly up regulated after 24 hour exposure to H2S. Data were RMA normalized and probe-level data were Summarized with the NimbleScan software. Genes with weak signal intensity across all groups and those with low variability across samples were excluded from further analysis. Each H2S-treated sample was statistically compared to a matched untreated control using the Bioconductor package limma. The false discovery rate (FDR) method of Benjamini and Hochberg was used to adjust p-values for multiple testing. An adjusted p-value <= 0.05 was used to define differential expression. WBPaper00040285:H2S_24hr_upregulated
  Transcripts that showed significantly increased expression in AFD neuron cells comparing to in whole animal, according to dissected single neuron RNASeq analysis. Fold change >= 4. WBPaper00050344:AFD-neuron_enriched
  Transcripts that showed significantly decreased expression by TCER-1 by comparing glp-1(e2141ts) with tcer-1(tm1452);glp-1(e2141ts) animals. The Cuffdiff Differential Gene Expression tool (version 0.0.5) was used to calculate differential gene expression using a false discovery rate of 0.05, a minimum alignment count of 100 and with bias correction to obtain gene and transcript expression level data along with fold change (in log2 scale) and P values (raw and corrected for multiple testing). WBPaper00049217:TCER-1_downregulated
  Genes significantely Up-regulated by GRO-seq in drh-3 (ne4253) vs. N2 using DESeq p<0.05 DESeq package with an FDR of < 0.05. WBPaper00045050:drh-3 (ne4253)_upregulated

3 Expression Patterns

Remark Reporter Gene Primary Identifier Pattern Subcellular Localization
    Expr1011715 Developmental gene expression time-course. Raw data can be downloaded from ftp://caltech.wormbase.org/pub/wormbase/datasets-published/levin2012  
    Expr1146321 Developmental gene expression time-course. Raw data can be downloaded from ftp://caltech.wormbase.org/pub/wormbase/datasets-published/hashimshony2015  
    Expr2019802 Single cell embryonic expression. Only cell types with an expression fraction of greater 0.2 of the maximum expressed fraction are labeled (Full data can be downloaded from http://caltech.wormbase.org/pub/wormbase/datasets-published/packer2019/). The colors represent the broad cell class to which the cell type has been assigned. The size of the point is proportional to the log2 of the numbers of cells in the dataset of that cell type. Interactive visualizations are available as a web app (https://cello.shinyapps.io/celegans/) and can also be installed as an R package (https://github.com/qinzhu/VisCello.celegans).  

0 GO Annotation

0 Homologues

1 Locations


Feature . Primary Identifier
Start End Strand
WBGene00044370 3012081 3012233 -1

0 Ontology Annotations

0 Regulates Expr Cluster

1 Sequence

Length
153

1 Sequence Ontology Term