WormMine: Gene WBGene00269383

• WormBase Gene ID: WBGene00269383
• Gene Name: ZK384.7
• Sequence Name: ZK384.7
• Organism: Caenorhabditis elegans
• Automated Description: Enriched in VD12; intestine; pharyngeal cell; and sensory neurons based on single-cell RNA-seq and microarray studies. Is affected by several genes including mut-16; rrf-3; and pptr-1 based on RNA-seq studies. Is affected by leptomycin B based on RNA-seq studies.
• Biotype: SO:0001263
• Genetic Position: :±
• Length (nt): 1097

1 Organism

• Name: Caenorhabditis elegans
• Taxon Id: 6239

1 Synonyms

• Value: WBGene00269383

Genomics

1 Transcripts

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
Transcript:ZK384.7	ZK384.7	441	V: 18736689-18737785

Other

0 CDSs

1 RNAi Result

• WBRNAi00021996

39 Allele

• gk963271
• gk963489
• gk963304
• gk963809
• gk963637
• WBVar02124841
• gk963292
• WBVar02120719
• gk962724
• WBVar02120528
• gk963480
• WBVar02123778
• WBVar02122704
• WBVar02062841
• WBVar01977661
• gk483627
• gk746062
• gk681897
• gk856549
• gk743717
• gk663321
• gk471472
• WBVar02124437
• WBVar02121811
• WBVar02121047
• WBVar02120720
• tm1972
• WBVar01875674
• gk263063
• gk263062

1 Chromosome

• WormBase ID: V
• Organism: Caenorhabditis elegans
• Length (nt): 20924180

1 Chromosome Location

• Feature . Primary Identifier: WBGene00269383
• Start: 18736689
• End: 18737785
• Strand: -1

2 Data Sets

• WormBaseAcedbConverter
• C. elegans genomic annotations (GFF3 Gene)

0 Downstream Intergenic Region

35 Expression Clusters

Regulated By Treatment	Description	Algorithm	Primary Identifier
	Transcripts that showed significantly increased expression in day 1 adult hermaphrodite comparing to in L4 larva glp-1(e2141) animals.	Fold change > 2, FDR < 0.05	WBPaper00064088:Day-1-adult_vs_L4_upregulated_glp-1(e2141)
	Transcripts that showed significantly increased expression in rrf-3(pk1426) comparing to in N2 at embryo stage.	DESeq2v 1.18.1, fold change > 1.5, adjusted p-value < 0.01.	WBPaper00056169:rrf-3(pk1426)_upregulated_embryo
	Transcripts that showed significantly increased expression in rrf-3(pk1426) comparing to in N2 at L3 larva stage.	DESeq2v 1.18.1, fold change > 1.5, adjusted p-value < 0.01.	WBPaper00056169:rrf-3(pk1426)_upregulated_L3
	Transcripts depleted in purified oocyte P bodies comparing to in the whole animal.	DESeq2, FDR < 0.05, fold change > 2.	WBPaper00065975:P-body_vs_WholeAnimal_depleted
	Transcripts that showed significantly increased expression in mut-16(pk710), comparing to in N2 animals.	DESeq2 v. 1.22.2, adjusted p-value <= 0.05.	WBPaper00059605:mut-16(pk710)_upregulated
	Transcripts that showed significantly increased expression in hda-2(ok1479) comparing to in N2 animals.	DESeq2 (version 1.28.1), FDR < 0.01, fold change > 2.	WBPaper00062159:hda-2(ok1479)_upregulated
	Transcripts that showed significantly increased expression in npr-15(tm12539) comparing to in N2 at L4 larva stage.	Fold change > 2, FDR < 0.05.	WBPaper00066608:npr-15(tm12539)_upregulated
	Single-cell RNA-Seq cell group 3_4 expressed in intestine.	scVI 0.6.0	WBPaper00065841:3_4
Temperature Shift: 25C vs 15C for 16 hours at L4 larva stage.	Transcripts that showed significantly increased expression in whole animal at lin-15(n765ts); oyIs95 animals shifted from 20C to 25C for 16 hours at L4 larva stage, comparing to animals shifted from 20C to 15C for 16 hours at L4 larva stage.	DESeq2, fold change > 2, FDR < 0.05.	WBPaper00065158:25C_vs_15C_upregulated_WholeAnimal
	Transcripts that showed significantly increased expression in rict-1(mg360) comparing to in N2 at day 1 adult stage.	DESeq2, FDR < 0.01, fold change > 2.	WBPaper00066970:rict-1(mg360)_upregulated
	Transcripts that showed significantly increased expression in pals-17(syb3980) comparing to in N2 animals at young adult stage.	Differential expression analyses were performed using limma-voom in Galaxy, adj p <= 0.05, logFC > 2	WBPaper00065984:pals-17(syb3980)_upregulated
	Genes enriched in intestine.	To identify genes that are significantly enriched by mRNA tagging, we first normalized the total amount of Cy3 and Cy5 signal to each other in each hybridization. We measured the ratio of the signals from the co-immunoprecipitated mRNA (Cy5) to total RNA in the cell extract (Cy3), and calculated the percentile rank for each gene relative to all genes in each hybridization. The mean percentile rank was determined from eight repeats of the mRNA-tagging experiment. Student's t-test was used to determine which genes showed a mean enrichment significantly greater than the median enrichment for all genes (P<0.001).	WBPaper00026980:intestine_enriched
Bacteria infection: Pseudomonas aeruginosa PA14. 24 hours of exposure.	Small RNAs (21-26nt) that showed significantly increased expression after L4 animals were exposed to P .aeruginosa strain PA14 for 24 hours.	DESeq2, FDR < 0.05	WBPaper00056868:P.aeruginosa_upregulated_smallRNA
	Transcripts that showed significantly increased expression in animals exposed to Leptomycin B for 3 hours at 2C.	p < 0.01, logFC > 1 or p < 0.01, logFC < -1.	WBPaper00066610:Leptomycin-B_upregulated_2C_3h
	Transcripts that showed significantly decreased expression in unc-30(ok613) animals at L4 larva stage, comparing to N2 animals.	Genes exhibiting at least two-fold change were considered differentially expressed.	WBPaper00061439:unc-30(ok613)_downregulated
	Single-cell RNA-Seq cell group 26_1 expressed in pharynx.	scVI 0.6.0	WBPaper00065841:26_1
	Transcripts that showed significantly increased expression in pals-22(jy3) comparing to in N2 animals.	limma-voom, fold change > 2, FDR < 0.05	WBPaper00064532:pals-22(jy3)_upregulated
Temperature Shift: 25C vs 15C for 16 hours at L4 larva stage.	Transcripts that showed significantly increased expression in AFD neurons at lin-15(n765ts); oyIs95 animals shifted from 20C to 25C for 16 hours at L4 larva stage, comparing to animals shifted from 20C to 15C for 16 hours at L4 larva stage.	DESeq2, fold change > 2, FDR < 0.05.	WBPaper00065158:25C_vs_15C_upregulated_AFD
	Transcripts that showed significantly increased expression in DLS357 [ceh-60(ok1485)] comparing to in N2 at day 4 adults.	DESeq2, fold change > 2, FDR < 0.01.	WBPaper00056550:ceh-60(ok1485)_upregulated_AdultDay4
	Transcripts that showed significantly increased expression in malt-1(db1194);npr-1(ad609) animals, in npr-1(ad609) ilc-17.1(tm5218) animals, and in npr-1(ad609) nfki-1(db1198) animals, comparing to the wild type control npr-1(ad609).	Cufflinks (v2.2.1). q < 0.05.	WBPaper00059609:malt-1_ilc-17.1_nfki-1_upregulated
	Transcripts that showed significantly increased expression in rrf-3(pk1426) comparing to in N2 at young adult stage.	DESeq2v 1.18.1, fold change > 1.5, adjusted p-value < 0.01.	WBPaper00056169:rrf-3(pk1426)_upregulated_adult
	Transcripts that showed significantly decreased expression in unc-30(ok613) animals at L4 larva stage after 4 hours of Pseudomonas aeruginosa infection, comparing to infected N2 animals.	Genes exhibiting at least two-fold change were considered differentially expressed.	WBPaper00061439:unc-30(ok613)_downregulated_P.aeruginosa-infection
	Targets of endo-siRNA that showed significantly increased expression in BFF39[pptr-1(tm3103);Pmex-5::gfp::h2b::tbb-2 (mjIs134 II)] comparing to in SX1263[Pmex-5::gfp::h2b::tbb-2 (mjIs134 II)] dissected gonad isolated from 1-day old adult hermaphrodites.	DESeq2, fold change > 2, FDR < 0.01	WBPaper00057140:pptr-1(tm3103)_upregulated
	Transcripts that showed significantly increased expression in rrf-3(pk1426) comparing to in N2 at L4 larva stage.	DESeq2v 1.18.1, fold change > 1.5, adjusted p-value < 0.01.	WBPaper00056169:rrf-3(pk1426)_upregulated_L4
	Genome-wide analysis of developmental and sex-regulated gene expression profile.	self-organizing map	cgc4489_group_7
	Transcripts that showed significantly increased expression in rrf-3(pk1426) comparing to in N2 at L2 larva stage.	DESeq2v 1.18.1, fold change > 1.5, adjusted p-value < 0.01.	WBPaper00056169:rrf-3(pk1426)_upregulated_L2
	Transcripts that showed significantly increased expression in postdauer adults comparing to adult animals that bypassed the dauger stage.	DESeq 2, FDR < 0.05.	WBPaper00064494:postdauer_upregulated_WholeAnimal
	Transcripts enriched in ADL according to single cell RNAseq.	Genes that pass the Bonferroni threshold for multiple comparisons (q < 0.05) are significantly enriched.	WBPaper00061651:ADL_enriched
	Transcripts enriched in ASH according to single cell RNAseq.	Genes that pass the Bonferroni threshold for multiple comparisons (q < 0.05) are significantly enriched.	WBPaper00061651:ASH_enriched
	Single-cell RNA-Seq cell group 54_0 expressed in neuron.	scVI 0.6.0	WBPaper00065841:54_0

0 Expression Patterns

0 GO Annotation

0 Homologues

1 Locations

• Feature . Primary Identifier: WBGene00269383
• Start: 18736689
• End: 18737785
• Strand: -1

0 Ontology Annotations

0 Regulates Expr Cluster

1 Sequence

• Length: 1097

1 Sequence Ontology Term