WormMine

WS295

Intermine data mining platform for C. elegans and related nematodes

Gene :

WormBase Gene ID  ? WBGene00197773 Gene Name  T27A10.8
Sequence Name  ? T27A10.8 Organism  Caenorhabditis elegans
Automated Description  Is affected by several genes including npr-8; emr-1; and hmg-3 based on RNA-seq and microarray studies. Is affected by five chemicals including Ethanol; sodium arsenite; and bisphenol A based on RNA-seq studies. Biotype  SO:0001263
Genetic Position  Length (nt)  ? 188
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1 Organism

Name Taxon Id
Caenorhabditis elegans 6239

1 Synonyms

Value
WBGene00197773

Genomics

1 Transcripts

WormMine ID Sequence Name Length (nt) Chromosome Location
Transcript:T27A10.8 T27A10.8 188   X: 3572379-3572566
 

Other

0 CDSs

0 RNAi Result

10 Allele

Public Name
gk963725
gk964260
gk962556
gk963502
WBVar02123553
WBVar02121347
WBVar02122052
gk340778
gk515133
gk276134

1 Chromosome

WormBase ID Organism Length (nt)
X Caenorhabditis elegans 17718942  

1 Chromosome Location


Feature . Primary Identifier
Start End Strand
WBGene00197773 3572379 3572566 1

2 Data Sets

Name URL
WormBaseAcedbConverter  
C. elegans genomic annotations (GFF3 Gene)  

1 Downstream Intergenic Region

WormBase ID Name Sequence Name Length (nt) Chromosome Location Organism
intergenic_region_chrX_3572567..3572843   277 X: 3572567-3572843 Caenorhabditis elegans

27 Expression Clusters

Regulated By Treatment Description Algorithm Primary Identifier
  Transcripts that showed significantly increased expression in day 1 adult hermaphrodite comparing to in L4 larva daf-16(mu86);glp-1(e2141) animals. Fold change > 2, FDR < 0.05 WBPaper00064088:Day-1-adult_vs_L4_upregulated_daf-16(mu86);glp-1(e2141)
  Transcripts that showed significantly increased expression in day 1 adult hermaphrodite comparing to in L4 larva fem-3(q20) animals. Fold change > 2, FDR < 0.05 WBPaper00064088:Day-1-adult_vs_L4_upregulated_fem-3(q20)
  Transcripts that showed significantly increased expression in day 1 adult hermaphrodite comparing to in L4 larva glp-1(e2141) animals. Fold change > 2, FDR < 0.05 WBPaper00064088:Day-1-adult_vs_L4_upregulated_glp-1(e2141)
  Transcripts that showed significantly increased expression in day 3 adult hermaphrodite comparing to in L4 larva fem-3(q20) animals. Fold change > 2, FDR < 0.05 WBPaper00064088:Day-3-adult_vs_L4_upregulated_fem-3(q20)
  Transcripts depleted in purified oocyte P bodies comparing to in the whole animal. DESeq2, FDR < 0.05, fold change > 2. WBPaper00065975:P-body_vs_WholeAnimal_depleted
  Transcripts that showed significantly increased expression in 10-days post L4 adult hermaphrodite N2 grown at 20C, comparing to in 1-day post L4 adult hermaphrodite N2 animals grown at 20C. CuffDiff, fold change > 2. WBPaper00065096:Day10_vs_Day1_upregulated
  Transcripts that showed significantly decreased expression in 10-days post L4 adult hermaphrodite npr-8(ok1439) animals grown at 20C, comparing to in N2 animals. CuffDiff, fold change > 2. WBPaper00065096:npr-8(ok1439)_downregulated_Day10_20C
  Transcripts that showed significantly increased expression in BAT525 [hmg-3 (tm2539) / dpy-5(e61) unc-13(e1091) I.] comparing to in N2 at 1-day post L4 adult hermaphrodite stage. DESeq 2, fold change > 4, adjusted p-value < 0.05. WBPaper00055013:hmg-3(bar24)_upregulated
  Genes that were not enriched in either spermatogenic fem-3(q96gf) nor oogenic fog-2(q71) gonads, according to RNAseq analysis. To identify differentially expressed transcripts, authors used R/Bioconductor package DESeq. WBPaper00045521:Gender_Neutral
  Transcripts that showed significantly increased expression in day 3 adult hermaphrodite comparing to in L4 larva daf-16(mu86);glp-1(e2141) animals. Fold change > 2, FDR < 0.05 WBPaper00064088:Day-3-adult_vs_L4_upregulated_daf-16(mu86);glp-1(e2141)
  Transcripts that showed significantly increased expression in day 3 adult hermaphrodite comparing to in L4 larva glp-1(e2141) animals. Fold change > 2, FDR < 0.05 WBPaper00064088:Day-3-adult_vs_L4_upregulated_glp-1(e2141)
  Genes that showed decreased mRNA expression in emr-1(RNAi);lem-2(tm1582) comparing to N2. Library siggenes in R was applied to select the differentially expressed loci using the false discovery rate-based SAM method. Genes presenting a delta value > 4 were considered to be significantly altered. WBPaper00044786:emr-1(RNAi);lem-2(tm1582)_downregulated
  Transcripts that showed significantly decreased expression in ogt-1(ok1474) neuronal cells isolated by FACs comparing to in FACs isolated neuronal cells from wild type. DESeq2, fold change > 2, FDR < 0.05. WBPaper00066485:ogt-1(ok1474)_downregulated_neuron
  Transcripts that showed significantly increased expression in N2 animals exposed to fluvastatin sodium for 9 hours at L4 larva stage, comparing to N2 animals grown without fluvastatin exposure. DESeq2 FDR < 0.05 WBPaper00059604:fluvastatin_upregulated_N2
  Transcripts that showed significantly decreased expression in lbp-3 overexpression transgenic lines comparing to wild type control animals. DESeq2 fold change > 2, FDR < 0.05. WBPaper00064156:lbp-3(overexpress)_downregulated
  Transcripts that showed significantly decreased expression in pmt-2(RNAi) animals comparing to control animals iinjected with empty vector. Fold-change > 1.5, ANOVA P values < 0.05. WBPaper00055482:pmt-2(RNAi)_downregulated
  Transcripts that showed significantly decreased expression after exposure to 500uM BPA (Bisphenol A), comparing to 0.1% ethanol control group. Cuffdiff was used to compare the aligned reads between the BPA- or BPS-treated group and the control ethanol group to identify genes and gene transcripts that were differentially expressed. Multiple hypothesis testing was corrected using the q value method to estimate false discovery rate (FDR). Genes and transcripts showing differential expression or alternative splicing at P < 0.05 were selected. WBPaper00049954:BPA_downregulated
  Genes that are significantly down regulated in tdp-1(ok803) poly(A) RNA-seq verses in N2. DESeq v1.14, with cut-off p-value < 0.05 and FDR < 0.1. WBPaper00046012:tdp-1(ok803)_downregulated
  Genes that showed decreased mRNA expression in emr-1(gk119) comparing to N2. Library siggenes in R was applied to select the differentially expressed loci using the false discovery rate-based SAM method. Genes presenting a delta value > 4 were considered to be significantly altered. WBPaper00044786:emr-1(gk119)_downregulated
  Genes that are upregulated by 0.2M ethanol treatment. Differences in gene expression levels between the two groups of worms were analyzed with Cufflinks 1.0.3, using a cutoff of twofold difference and FDR corrected p < 0.05. WBPaper00041954:ethanol_upregulated
  Transcripts that showed significantly decreased expression in mafr-1(tm6082) (gain of function) animals comparing to in N2. Student's t-test. Fold Change > = 2. WBPaper00050522:mafr-1(tm6082)_downregulated
  Genes that showed decreased mRNA expression in both ahr-1(ia03) and ahr-1(ju145) comparing to in N2. Both of the ahr-1 mutants studied when compared to wild-type N2 according to the criteria of fold change > 2 or < 0.5, FDR-corrected p-value of < 0.05 and FPKM of > 0 in both samples. WBPaper00044753:ahr-1_downregulated
  Genes that showed significantly changed expression in oxidative stressed N2 animals caused by 10mM sodium arsenite (NaAsO2) comparing to in unstressed N2. R-Bioconductor package. WBPaper00049266:NaAsO2-Stress_regulated_N2
  Transcripts that showed significantly increased expression in dlk-1(km12) animals exposed to fluvastatin sodium for 9 hours at L4 larva stage, comparing to dlk-1(km12) animals grown without fluvastatin exposure. DESeq2 FDR < 0.05 WBPaper00059604:fluvastatin_upregulated_dlk-1(km12)
  Transcripts that showed significantly decreased expression in set-26(tm2467) animals comparing to in N2. edgeR, 5% FDR. WBPaper00054410:set-26(tm2467)_downregulated
  Transcripts that showed significantly decreased expression after exposure to 500uM BPS (Bisphenol S), comparing to 0.1% ethanol control group. Cuffdiff was used to compare the aligned reads between the BPA- or BPS-treated group and the control ethanol group to identify genes and gene transcripts that were differentially expressed. Multiple hypothesis testing was corrected using the q value method to estimate false discovery rate (FDR). Genes and transcripts showing differential expression or alternative splicing at P < 0.05 were selected. WBPaper00049954:BPS_downregulated
  Transcripts that showed significantly increased expression in ifo-1(kc2) comparing to in N2 animals. ANOVA, p-value < 0.05. WBPaper00056167:ifo-1(kc2)_upregulated

0 Expression Patterns

0 GO Annotation

0 Homologues

1 Locations


Feature . Primary Identifier
Start End Strand
WBGene00197773 3572379 3572566 1

0 Ontology Annotations

0 Regulates Expr Cluster

1 Sequence

Length
188

1 Sequence Ontology Term