WormMine: Gene WBGene00014612

• WormBase Gene ID: WBGene00014612
• Gene Name: mir-354
• Sequence Name: Y105E8A.31
• Brief Description: mir-354 encodes a microRNA, a small non-protein coding RNA and seems to be conserved in C. briggsae; many of the known microRNAs are involved in post-transcriptional regulation of genes; the precise function of miR-354 is unknown.
• Organism: Caenorhabditis elegans
• Automated Description: Is affected by several genes including hrpk-1; alg-1; and alg-2 based on tiling array and RNA-seq studies.
• Biotype: SO:0001265
• Genetic Position: I :25.7125 ±0.003155
• Length (nt): 110

1 Organism

• Name: Caenorhabditis elegans
• Taxon Id: 6239

1 Synonyms

• Value: WBGene00014612

Genomics

2 Transcripts

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
Transcript:Y105E8A.31a	Y105E8A.31a	21	I: 14468392-14468412
Transcript:Y105E8A.31b	Y105E8A.31b	21	I: 14468451-14468471

Other

0 CDSs

0 RNAi Result

6 Allele

• gk963849
• gk964175
• gk962681
• gk963947
• gk963269
• gk129338

1 Chromosome

• WormBase ID: I
• Organism: Caenorhabditis elegans
• Length (nt): 15072434

1 Chromosome Location

• Feature . Primary Identifier: WBGene00014612
• Start: 14468382
• End: 14468491
• Strand: -1

2 Data Sets

• WormBaseAcedbConverter
• C. elegans genomic annotations (GFF3 Gene)

0 Downstream Intergenic Region

5 Expression Clusters

Regulated By Treatment	Description	Algorithm	Primary Identifier
	Potental DAF-12 target genes identified by ChIP-chip analysis performed on strain ALF4 [daf-12	Affymetrix TAS software that computed for each probe estimates of fold enrichment (in linear scale) over hybridization with input DNA. At the same time, TAS calculated for each probe a p-value by applying a Wilcoxon signed rank test. A threshold of 2.5 was selected, which corresponds to probe intensities approximately 2.5 times stronger on the ChIP array than on the Input array. Additional TAS threshold parameters were MinRun=180 bp, MaxGap=300 bp. TAS analysis showed that the selected threshold of 2.5 corresponds approximately to a p-value of 0.01.	WBPaper00040221:DAF-12_target_ALF4
	Micro RNAs that showed significantly decreased expression in hrpk-1(tm5522) comparing to in N2 at L4 larva stage.	DESeq, fold change > 2, p-value <= 0.05.	WBPaper00058673:hrpk-1(tm5522)_downregulated_miRNA_L4
	MicroRNAs that showed significantly decreased expression in alg-2(ok304), comparing to in N2.	DESeq2, Fold change > 1.5.	WBPaper00051404:alg-2(ok304)_downregulated_miRNA
	MicroRNAs that showed significantly increased expression in alg-5(ram2), comparing to in N2.	DESeq2, Fold change > 1.5.	WBPaper00051404:alg-5(ram2)_upregulated_miRNA
	MicroRNAs that showed significantly increased expression in alg-1(gk214), comparing to in N2.	DESeq2, Fold change > 1.5.	WBPaper00051404:alg-1(gk214)_upregulated_miRNA

0 Expression Patterns

0 GO Annotation

0 Homologues

1 Locations

• Feature . Primary Identifier: WBGene00014612
• Start: 14468382
• End: 14468491
• Strand: -1

0 Ontology Annotations

0 Regulates Expr Cluster

1 Sequence

• Length: 110

1 Sequence Ontology Term