WormMine

WS297

Intermine data mining platform for C. elegans and related nematodes

GO Term : GO:0005874 microtubule GO

Namespace  cellular_component Obsolete  false
Description  Any of the long, generally straight, hollow tubes of internal diameter 12-15 nm and external diameter 24 nm found in a wide variety of eukaryotic cells; each consists (usually) of 13 protofilaments of polymeric tubulin, staggered in such a manner that the tubulin monomers are arranged in a helical pattern on the microtubular surface, and with the alpha/beta axes of the tubulin subunits parallel to the long axis of the tubule; exist in equilibrium with pool of tubulin monomers and can be rapidly assembled or disassembled in response to physiological stimuli; concerned with force generation, e.g. in the spindle.

0 Cross References

1 Data Sets

Name URL
GO Annotation data set  

1 Ontology

Name
GO

333 Ontology Annotations

Annotation Extension Qualifier
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14 Parents

Identifier Name Description
GO:0005575 cellular_component A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-enclosed compartments (e.g., mitochondrion); (2) virion components, where viral proteins act, and (3) the stable macromolecular complexes of which gene product are parts (e.g., the clathrin complex).
GO:0005622 intracellular anatomical structure A component of a cell contained within (but not including) the plasma membrane. In eukaryotes it includes the nucleus and cytoplasm.
GO:0110165 cellular anatomical structure A part of a cellular organism consisting of a material entity with granularity above the level of a protein complex but below that of an anatomical system. Note that cellular organisms exclude viruses.
GO:0043226 organelle Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, and prokaryotic structures such as anammoxosomes and pirellulosomes. Excludes the plasma membrane.
GO:0043229 intracellular organelle Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.
GO:0043228 membraneless organelle Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane. Includes ribosomes, the cytoskeleton and chromosomes.
GO:0043232 intracellular membraneless organelle Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane and occurring within the cell. Includes ribosomes, the cytoskeleton and chromosomes.
GO:0005856 cytoskeleton A cellular structure that forms the internal framework of eukaryotic and prokaryotic cells. The cytoskeleton includes intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the cell. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles.
GO:0099080 supramolecular complex A cellular component that consists of an indeterminate number of proteins or macromolecular complexes, organized into a regular, higher-order structure such as a polymer, sheet, network or a fiber.
GO:0005874 microtubule Any of the long, generally straight, hollow tubes of internal diameter 12-15 nm and external diameter 24 nm found in a wide variety of eukaryotic cells; each consists (usually) of 13 protofilaments of polymeric tubulin, staggered in such a manner that the tubulin monomers are arranged in a helical pattern on the microtubular surface, and with the alpha/beta axes of the tubulin subunits parallel to the long axis of the tubule; exist in equilibrium with pool of tubulin monomers and can be rapidly assembled or disassembled in response to physiological stimuli; concerned with force generation, e.g. in the spindle.
GO:0099512 supramolecular fiber A polymer consisting of an indefinite number of protein or protein complex subunits that have polymerised to form a fiber-shaped structure.
GO:0099513 polymeric cytoskeletal fiber A component of the cytoskeleton consisting of a homo or heteropolymeric fiber constructed from an indeterminate number of protein subunits.
GO:0015630 microtubule cytoskeleton The part of the cytoskeleton (the internal framework of a cell) composed of microtubules and associated proteins.
GO:0099081 supramolecular polymer A polymeric supramolecular structure.

81 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0005874 GO:0000235
is_a GO:0005874 GO:0005827
is_a GO:0005874 GO:0005828
is_a GO:0099513 GO:0005874
part of GO:0015630 GO:0005874
part of GO:0005622 GO:0005874
part of GO:0005856 GO:0005874
is_a GO:0099512 GO:0005874
is_a GO:0110165 GO:0005874
part of GO:0043226 GO:0005874
part of GO:0043232 GO:0005874
is_a GO:0005575 GO:0005874
is_a GO:0099080 GO:0005874
is_a GO:0099081 GO:0005874
part of GO:0005575 GO:0005874
part of GO:0043229 GO:0005874
part of GO:0043228 GO:0005874
part of GO:0110165 GO:0005874
is_a GO:0005874 GO:0005876
is_a GO:0005874 GO:0005876
is_a GO:0005874 GO:0005879
is_a GO:0005874 GO:0005879
is_a GO:0005874 GO:0005880
is_a GO:0005874 GO:0005880
is_a GO:0005874 GO:0005881
is_a GO:0005874 GO:0005881
has part GO:0005874 GO:0005930
is_a GO:0005874 GO:0010005
is_a GO:0005874 GO:0020025
is_a GO:0005874 GO:0033289

3 Synonyms

Name Type
microtubuli synonym
neurotubule synonym
microtubulus synonym