WormMine

WS297

Intermine data mining platform for C. elegans and related nematodes

GO Term : GO:0001913 T cell mediated cytotoxicity GO

Namespace  biological_process Obsolete  false
Description  The directed killing of a target cell by a T cell through the release of granules containing cytotoxic mediators or through the engagement of death receptors.

0 Cross References

0 Data Sets

1 Ontology

Name
GO

0 Ontology Annotations

14 Parents

Identifier Name Description
GO:0009987 cellular process Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0008150 biological_process A biological process is the execution of a genetically-encoded biological module or program. It consists of all the steps required to achieve the specific biological objective of the module. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence.
GO:0050896 response to stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism.
GO:0002376 immune system process Any process involved in the development or functioning of the immune system, an organismal system for calibrated responses to potential internal or invasive threats.
GO:0001909 leukocyte mediated cytotoxicity The directed killing of a target cell by a leukocyte.
GO:0002449 lymphocyte mediated immunity Any process involved in the carrying out of an immune response by a lymphocyte.
GO:0002443 leukocyte mediated immunity Any process involved in the carrying out of an immune response by a leukocyte.
GO:0006955 immune response Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat.
GO:0002250 adaptive immune response An immune response mediated by cells expressing specific receptors for antigens produced through a somatic diversification process, and allowing for an enhanced secondary response to subsequent exposures to the same antigen (immunological memory).
GO:0002252 immune effector process Any process of the immune system that executes a component of an immune response. An effector immune process takes place after its activation.
GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains An immune response mediated by lymphocytes expressing specific receptors for antigen produced through a somatic diversification process that includes somatic recombination of germline gene segments encoding immunoglobulin superfamily domains. Recombined receptors for antigen encoded by immunoglobulin superfamily domains include T cell receptors and immunoglobulins (antibodies) produced by B cells. The first encounter with antigen elicits a primary immune response that is slow and not of great magnitude. T and B cells selected by antigen become activated and undergo clonal expansion. A fraction of antigen-reactive T and B cells become memory cells, whereas others differentiate into effector cells. The memory cells generated during the primary response enable a much faster and stronger secondary immune response upon subsequent exposures to the same antigen (immunological memory). An example of this is the adaptive immune response found in Mus musculus.
GO:0001906 cell killing Any process in an organism that results in the killing of its own cells or those of another organism, including in some cases the death of the other organism. Killing here refers to the induction of death in one cell by another cell, not cell-autonomous death due to internal or other environmental conditions.
GO:0002456 T cell mediated immunity Any process involved in the carrying out of an immune response by a T cell.
GO:0001913 T cell mediated cytotoxicity The directed killing of a target cell by a T cell through the release of granules containing cytotoxic mediators or through the engagement of death receptors.

35 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0001909 GO:0001913
is_a GO:0002456 GO:0001913
is_a GO:0008150 GO:0001913
is_a GO:0006955 GO:0001913
is_a GO:0002449 GO:0001913
is_a GO:0002250 GO:0001913
is_a GO:0009987 GO:0001913
is_a GO:0002252 GO:0001913
is_a GO:0002460 GO:0001913
is_a GO:0001906 GO:0001913
is_a GO:0002443 GO:0001913
is_a GO:0050896 GO:0001913
is_a GO:0002376 GO:0001913
regulates GO:0001913 GO:0001914
regulates GO:0001913 GO:0001914
negatively regulates GO:0001913 GO:0001915
negatively regulates GO:0001913 GO:0001915
regulates GO:0001913 GO:0001915
positively regulates GO:0001913 GO:0001916
positively regulates GO:0001913 GO:0001916
regulates GO:0001913 GO:0001916
is_a GO:0001913 GO:0002419
regulates GO:0001913 GO:0002852
negatively regulates GO:0001913 GO:0002853
regulates GO:0001913 GO:0002853
regulates GO:0001913 GO:0002854
positively regulates GO:0001913 GO:0002854
part of GO:0001913 GO:0043316
regulates GO:0001913 GO:0043317
regulates GO:0001913 GO:0043318

10 Synonyms

Name Type
T cell mediated cytolysis synonym
T cell mediated cell killing synonym
T-cell mediated apoptosis synonym
T lymphocyte mediated cytotoxicity synonym
T-cell mediated cell killing synonym
T-cell mediated cell death synonym
T-lymphocyte mediated cytotoxicity synonym
T-cell mediated cytotoxicity synonym
T cell mediated cell death synonym
T cell mediated apoptosis synonym