WormMine

WS297

Intermine data mining platform for C. elegans and related nematodes

GO Term : GO:0043316 cytotoxic T cell degranulation GO

Namespace  biological_process Obsolete  false
Description  The regulated exocytosis of secretory granules containing preformed mediators such as perforin and granzymes by a cytotoxic T cell.

0 Cross References

0 Data Sets

1 Ontology

Name
GO

0 Ontology Annotations

47 Parents

Identifier Name Description
GO:0006996 organelle organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an organelle within a cell. An organelle is an organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.
GO:0009987 cellular process Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0051179 localization Any process in which a cell, a substance, or a cellular entity, such as a protein complex or organelle, is transported, tethered to or otherwise maintained in a specific location. In the case of substances, localization may also be achieved via selective degradation.
GO:0008150 biological_process A biological process is the execution of a genetically-encoded biological module or program. It consists of all the steps required to achieve the specific biological objective of the module. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence.
GO:0071840 cellular component organization or biogenesis A process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cellular component.
GO:0016043 cellular component organization A process that results in the assembly, arrangement of constituent parts, or disassembly of a cellular component.
GO:0051234 establishment of localization Any process that localizes a substance or cellular component. This may occur via movement, tethering or selective degradation.
GO:0006810 transport The directed movement of substances (such as macromolecules, small molecules, ions) or cellular components (such as complexes and organelles) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or a transporter complex, a pore or a motor protein.
GO:0050896 response to stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism.
GO:0051649 establishment of localization in cell Any process, occurring in a cell, that localizes a substance or cellular component. This may occur via movement, tethering or selective degradation.
GO:0051641 cellular localization A cellular localization process whereby a substance or cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in, a specific location within a cell including the localization of substances or cellular entities to the cell membrane.
GO:0061024 membrane organization A process which results in the assembly, arrangement of constituent parts, or disassembly of a membrane. A membrane is a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.
GO:0016192 vesicle-mediated transport A cellular transport process in which transported substances are moved in membrane-bounded vesicles; transported substances are enclosed in the vesicle lumen or located in the vesicle membrane. The process begins with a step that directs a substance to the forming vesicle, and includes vesicle budding and coating. Vesicles are then targeted to, and fuse with, an acceptor membrane.
GO:0032501 multicellular organismal process Any biological process, occurring at the level of a multicellular organism, pertinent to its function.
GO:0090174 organelle membrane fusion The joining of two lipid bilayers to form a single organelle membrane.
GO:0048284 organelle fusion The creation of a single organelle from two or more organelles.
GO:0061025 membrane fusion The membrane organization process that joins two lipid bilayers to form a single membrane.
GO:0016050 vesicle organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a vesicle.
GO:0046903 secretion The controlled release of a substance by a cell or a tissue.
GO:0046649 lymphocyte activation A change in morphology and behavior of a lymphocyte resulting from exposure to a specific antigen, mitogen, cytokine, chemokine, cellular ligand, or soluble factor.
GO:0045321 leukocyte activation A change in morphology and behavior of a leukocyte resulting from exposure to a specific antigen, mitogen, cytokine, cellular ligand, or soluble factor.
GO:0001775 cell activation A multicellular organismal process by which exposure to an activating factor such as a cellular or soluble ligand results in a change in the morphology or behavior of a cell.
GO:0002376 immune system process Any process involved in the development or functioning of the immune system, an organismal system for calibrated responses to potential internal or invasive threats.
GO:0042110 T cell activation The change in morphology and behavior of a mature or immature T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.
GO:0001909 leukocyte mediated cytotoxicity The directed killing of a target cell by a leukocyte.
GO:0002449 lymphocyte mediated immunity Any process involved in the carrying out of an immune response by a lymphocyte.
GO:0002443 leukocyte mediated immunity Any process involved in the carrying out of an immune response by a leukocyte.
GO:0006955 immune response Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat.
GO:0002250 adaptive immune response An immune response mediated by cells expressing specific receptors for antigens produced through a somatic diversification process, and allowing for an enhanced secondary response to subsequent exposures to the same antigen (immunological memory).
GO:0002252 immune effector process Any process of the immune system that executes a component of an immune response. An effector immune process takes place after its activation.

61 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
part of GO:0001913 GO:0043316
is_a GO:0043299 GO:0043316
part of GO:0002286 GO:0043316
is_a GO:0006887 GO:0043316
part of GO:0001906 GO:0043316
is_a GO:0051179 GO:0043316
part of GO:0001909 GO:0043316
has part GO:0140029 GO:0043316
part of GO:0051641 GO:0043316
is_a GO:0046903 GO:0043316
part of GO:0006955 GO:0043316
is_a GO:0045055 GO:0043316
part of GO:0045321 GO:0043316
is_a GO:0051649 GO:0043316
has part GO:0009987 GO:0043316
part of GO:0009987 GO:0043316
is_a GO:0009987 GO:0043316
part of GO:0008150 GO:0043316
is_a GO:0032940 GO:0043316
has part GO:0008150 GO:0043316
part of GO:0032501 GO:0043316
part of GO:0002285 GO:0043316
part of GO:0051179 GO:0043316
has part GO:0071840 GO:0043316
part of GO:0002449 GO:0043316
has part GO:0016043 GO:0043316
part of GO:0002443 GO:0043316
part of GO:0002366 GO:0043316
has part GO:0048284 GO:0043316
part of GO:0042110 GO:0043316

7 Synonyms

Name Type
cytotoxic T cell granule exocytosis synonym
cytotoxic T lymphocyte granule exocytosis synonym
cytotoxic T lymphocyte degranulation synonym
cytotoxic T-cell granule exocytosis synonym
cytotoxic T-cell degranulation synonym
cytotoxic T-lymphocyte granule exocytosis synonym
cytotoxic T-lymphocyte degranulation synonym