29 Parents
| Identifier | Name | Description |
|---|---|---|
| GO:0032991 | protein-containing complex | A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together. |
| GO:0005575 | cellular_component | A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-enclosed compartments (e.g., mitochondrion); (2) virion components, where viral proteins act, and (3) the stable macromolecular complexes of which gene product are parts (e.g., the clathrin complex). |
| GO:0005622 | intracellular anatomical structure | A component of a cell contained within (but not including) the plasma membrane. In eukaryotes it includes the nucleus and cytoplasm. |
| GO:0110165 | cellular anatomical structure | A part of a cellular organism consisting of a material entity with granularity above the level of a protein complex but below that of an anatomical system. Note that cellular organisms exclude viruses. |
| GO:0140513 | nuclear protein-containing complex | A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together in the nucleus. |
| GO:0043227 | membrane-bounded organelle | Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane. |
| GO:0043226 | organelle | Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, and prokaryotic structures such as anammoxosomes and pirellulosomes. Excludes the plasma membrane. |
| GO:0005634 | nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
| GO:0043229 | intracellular organelle | Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane. |
| GO:0043231 | intracellular membrane-bounded organelle | Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane. |
| GO:0031974 | membrane-enclosed lumen | The enclosed volume within a sealed membrane or between two sealed membranes. Encompasses the volume enclosed by the membranes of a particular organelle, e.g. endoplasmic reticulum lumen, or the space between the two lipid bilayers of a double membrane surrounding an organelle, e.g. nuclear envelope lumen. |
| GO:0031981 | nuclear lumen | The volume enclosed by the nuclear inner membrane. |
| GO:0070013 | intracellular organelle lumen | An organelle lumen that is part of an intracellular organelle. |
| GO:0043233 | organelle lumen | The internal volume enclosed by the membranes of a particular organelle; includes the volume enclosed by a single organelle membrane, e.g. endoplasmic reticulum lumen, or the volume enclosed by the innermost of the two lipid bilayers of an organelle envelope, e.g. nuclear lumen. |
| GO:0043228 | membraneless organelle | Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane. Includes ribosomes, the cytoskeleton and chromosomes. |
| GO:0043232 | intracellular membraneless organelle | Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane and occurring within the cell. Includes ribosomes, the cytoskeleton and chromosomes. |
| GO:0005694 | chromosome | A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information. |
| GO:0000228 | nuclear chromosome | A chromosome that encodes the nuclear genome and is found in the nucleus of a eukaryotic cell during the cell cycle phases when the nucleus is intact. |
| GO:0032993 | protein-DNA complex | A macromolecular complex containing both protein and DNA molecules. |
| GO:0000808 | origin recognition complex | A multisubunit complex that is located at the replication origins of a chromosome. |
| GO:0000811 | GINS complex | A heterotetrameric protein complex that associates with replication origins, where it is required for the initiation of DNA replication, and with replication forks. |
| GO:0031261 | DNA replication preinitiation complex | A protein-DNA complex assembled at eukaryotic DNA replication origins immediately prior to the initiation of DNA replication. The preinitiation complex is formed by the assembly of additional proteins onto an existing prereplicative complex. In budding yeast, the additional proteins might include Cdc45p, Sld2p, Sld3p, Dpb11p, DNA polymerases, and others; in fission yeast the GINS complex is present. |
| GO:0097373 | MCM core complex | A protein complex that contains Mcm4, Mcm6, and Mcm7 proteins, and possesses DNA helicase activity. In the heterohexameric MCM complex, the Mcm4/6/7 proteins form a stable core, and Mcm2, Mcm3, and Mcm5 are more peripherally associated. |
| GO:0005656 | nuclear pre-replicative complex | A protein-DNA complex assembled at eukaryotic DNA replication origins during late mitosis and G1, allowing the origin to become competent, or 'licensed', for replication. The complex normally includes the origin recognition complex (ORC), Cdc6, Cdt1 and the MiniChromosome Maintenance (Mcm2-7) proteins. |
| GO:0036387 | pre-replicative complex | A protein-DNA complex that forms at the origin of replication during the initial step of DNA replication and allows the origin to become competent, or 'licensed', for replication. |
| GO:0042555 | MCM complex | A hexameric protein complex required for the initiation and regulation of DNA replication. |
| GO:0005657 | replication fork | The Y-shaped region of a replicating DNA molecule, resulting from the separation of the DNA strands and in which the synthesis of new strands takes place. Also includes associated protein complexes. |
| GO:0043596 | nuclear replication fork | The Y-shaped region of a nuclear replicating DNA molecule, resulting from the separation of the DNA strands and in which the synthesis of new strands takes place. Also includes associated protein complexes. |
| GO:0071162 | CMG complex | A protein complex that contains the GINS complex, Cdc45p, and the heterohexameric MCM complex, and that is involved in unwinding DNA during replication. |
40 Relations
| Relationship |
Parent Term . Identifier |
Child Term . Identifier |
|---|---|---|
| part of | GO:0043596 | GO:0005658 |
| part of | GO:0043596 | GO:0005662 |
| part of | GO:0043596 | GO:0031298 |
| is_a | GO:0005657 | GO:0043596 |
| part of | GO:0000228 | GO:0043596 |
| is_a | GO:0005657 | GO:0043596 |
| has part | GO:0071162 | GO:0043596 |
| part of | GO:0005634 | GO:0043596 |
| part of | GO:0043229 | GO:0043596 |
| part of | GO:0043228 | GO:0043596 |
| part of | GO:0043227 | GO:0043596 |
| has part | GO:0097373 | GO:0043596 |
| part of | GO:0031981 | GO:0043596 |
| part of | GO:0043226 | GO:0043596 |
| has part | GO:0005656 | GO:0043596 |
| part of | GO:0005694 | GO:0043596 |
| has part | GO:0005575 | GO:0043596 |
| part of | GO:0005622 | GO:0043596 |
| part of | GO:0110165 | GO:0043596 |
| is_a | GO:0005575 | GO:0043596 |
| has part | GO:0036387 | GO:0043596 |
| has part | GO:0000811 | GO:0043596 |
| has part | GO:0140513 | GO:0043596 |
| part of | GO:0043233 | GO:0043596 |
| part of | GO:0031974 | GO:0043596 |
| part of | GO:0043232 | GO:0043596 |
| has part | GO:0042555 | GO:0043596 |
| part of | GO:0043231 | GO:0043596 |
| has part | GO:0031261 | GO:0043596 |
| part of | GO:0005634 | GO:0043596 |
