WormMine

WS297

Intermine data mining platform for C. elegans and related nematodes

GO Term : GO:0061815 Met1-linked polyubiquitin deubiquitinase activity GO
Namespace  molecular_function Obsolete  false
Description  Catalysis of the hydrolysis of ubiquitin units from Met1-linked (or linear) polyubiquitin chains.
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0 Cross References

0 Data Sets

1 Ontology

Name
GO

0 Ontology Annotations

10 Parents

Identifier Name Description
GO:0003674 molecular_function A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs.
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0016787 hydrolase activity Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc.
GO:0140096 catalytic activity, acting on a protein Catalytic activity that acts to modify a protein.
GO:0008233 peptidase activity Catalysis of the hydrolysis of a peptide bond. A peptide bond is a covalent bond formed when the carbon atom from the carboxyl group of one amino acid shares electrons with the nitrogen atom from the amino group of a second amino acid.
GO:0008234 cysteine-type peptidase activity Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile.
GO:0101005 deubiquitinase activity An isopeptidase activity that cleaves ubiquitin from a target protein to which it is conjugated.
GO:0004843 cysteine-type deubiquitinase activity An thiol-dependent isopeptidase activity that cleaves ubiquitin from a target protein to which it is conjugated.
GO:0019783 ubiquitin-like protein peptidase activity An isopeptidase activity that cleaves ubiquitin or ubiquitin-like proteins (ULP; e.g. ATG8, ISG15, NEDD8, SUMO) from target proteins.
GO:0061815 Met1-linked polyubiquitin deubiquitinase activity Catalysis of the hydrolysis of ubiquitin units from Met1-linked (or linear) polyubiquitin chains.

9 Relations

Relationship
Parent Term . Identifier
Child Term . Identifier
is_a GO:0004843 GO:0061815
is_a GO:0101005 GO:0061815
is_a GO:0016787 GO:0061815
is_a GO:0003674 GO:0061815
is_a GO:0140096 GO:0061815
is_a GO:0008233 GO:0061815
is_a GO:0008234 GO:0061815
is_a GO:0019783 GO:0061815
is_a GO:0003824 GO:0061815

5 Synonyms

Name Type
cysteine-type deubiquitinase activity, acting on linear ubiquitin synonym
linear ubiquitin specific deubiquitinase activity synonym
deubiquitinase, acting on linear ubiquitin synonym
ubiquitinyl hydrolase activity, acting on linear ubiquitin synonym
Met1 linkage specific DUB synonym