WormMine: ExpressionPattern Expr11487

• Pattern: The die-1 fosmid reporter is initially expressed very broadly throughout the developing embryo, including the hypodermis, where die-1 acts to ensure ventral enclosure during gastrulation. Mirroring antibody staining, reporter expression of the fosmid reporter vanishes at approximately 460 min of embryonic development. die-1 expression then reinitiates in many neurons,including both ASEL and ASER; shortly thereafter, expression in ASER becomes undetectable. ASEL-restricted expression is maintained throughout the embryonic, larval, and adult stages. die-1 is also expressed in an asymmetric manner in the AWC olfactory neuron pair. Most adult animals show a strong bias of expression of die-1 to either the left or right AWC neuron. This antisymmetric die-1 expression is already evident in late embryos when the initial decision of AWC asymmetry control is made. ASEL-specific expression of die-1can be observed before any AWC expression of die-1 is observed. Expression of the die-1 fosmid reporter correlates with the AWC OFF state.
• Primary Identifier: Expr11487
• Remark: Temporal description

6 Anatomy Terms

Definition	Name	Synonym	Primary Identifier
Epidermal layer.	hypodermis	epidermis	WBbt:0005733
Major cell type of nervous tissue, specialized for transmission of information in the form of patterns of impulses.	neuron	neurone	WBbt:0003679
one member of Amphid neurons, single ciliated endings, probably chemo-sensory; project into ring via commissure from ventral ganglion, make diverse synaptic connections in ring neuropil	ASEL	lineage name: ABalppppppaa	WBbt:0003904
one member of Amphid neurons, single ciliated endings, probably chemo-sensory; project into ring via commissure from ventral ganglion, make diverse synaptic connections in ring neuropil	ASER	lineage name: ABpraaapppaa	WBbt:0003903
one of the two AWC neurons, stochastically determined, in which the str-2 promoter is inactive	AWC-OFF		WBbt:0005833
cell that exists in and is part of an embryo.	embryonic cell		WBbt:0007028

1 Genes

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00000995	die-1	C18D1.1	Caenorhabditis elegans

0 Life Stages