WormMine: ExpressionPattern Expr12377

• Pattern: TSP-21::GFP is plasma membrane-localized and is expressed in a wide variety of somatic cell types, including the pharynx, intestine and hypodermis starting in embryos after the 100 cell stage and peaking in L1 and L2 larvae. The TSP-21::GFP signal in these tissues decreases in late larval and adult stage animals. TSP-21::GFP is also present at the surface of M lineage cells from the 1-M stage to the 16-M stage. TSP-21::GFP is enriched in the basolateral side of intestinal cells while being absent from their apical sides. In addition, while TSP-21::GFP in the M lineage cells is primarily plasma membrane localized, there is also a significant intracellular distribution of TSP-21::GFP in the M mesoblast.
• Primary Identifier: Expr12377

6 Anatomy Terms

Definition	Name	Synonym	Primary Identifier
A chain of very large cuboidal cells forming a wide central lumen in which food arrives from the posterior pharynx, is digested, and from which waste products proceed to the rectum. Intestinal rings form in groups of two and four cells surrounding the common lumen; thus the epithelium is only one cell deep at any point, with neighboring cells firmly secured to their neighbors by apical adherens junctions. These cells have very large nuclei and many large vacuoles, yolk granules, and other inclusions; the latter increase in number and electron density as the animal ages.	intestine	gut	WBbt:0005772
Epidermal layer.	hypodermis	epidermis	WBbt:0005733
the feeding organ, a neuro-muscular pump in the head of the animal, used to ingest food, bacteria suspended in liquid, filter them out, grind them up and transport posteriorly into the instestine.	pharynx	esophagus	WBbt:0003681
organ producing either sperm or ova.	gonad		WBbt:0005175
epithelium connecting intestine and anus.	rectal epithelium		WBbt:0005800
A cell that is the M blast cell or is a lineal descendant of M.	M lineage cell		WBbt:0008439

1 Genes

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00023491	tsp-21	C17G1.8	Caenorhabditis elegans

3 Life Stages

Remark	Definition	Other Name	Public Name	Primary Identifier
	The stage that begins when a C.elegans individual is fully-developed and has reached maturity.		adult Ce	WBls:0000041
	The whole period of embryogenesis in the nematode Caenorhabditis elegans, from the formation of an egg until hatching.		embryo Ce	WBls:0000003
	A developmental life stage of the nematode Caenorhabditis elegans that occurs from egg hatching until adulthood.		larva Ce	WBls:0000023