WormMine: ExpressionPattern Expr1904

• Pattern: Wild-type embryos were stained with AS1 and examined by immunofluorescence microscopy. In early embryos, alpha-spectrin is found at or near the cell membrane in most if not all cells starting at the earliest stage of embryogenesis, indicating that alpha-spectrin is maternally supplied. After morphogenesis and organogenesis initiates, alpha-spectrin localizes to the body wall muscle, hypodermis, pharynx, intestine, and developing nervous system. In epithelial tissues, alpha-spectrin is found at both the apical and basolateral regions of the membrane. This is unlike the localization pattern observed for beta-spectrin, which is found in only the basolateral region of the membrane. With the exception of the apical regions, the localization of alpha-spectrin overlaps with the distribution of beta-spectrin.
• Primary Identifier: Expr1904
• Remark: No details on expression pattern at other stages. spc-1 = alpha-spectrin
• Subcellular Localization: membrane

5 Anatomy Terms

Definition	Name	Synonym	Primary Identifier
A chain of very large cuboidal cells forming a wide central lumen in which food arrives from the posterior pharynx, is digested, and from which waste products proceed to the rectum. Intestinal rings form in groups of two and four cells surrounding the common lumen; thus the epithelium is only one cell deep at any point, with neighboring cells firmly secured to their neighbors by apical adherens junctions. These cells have very large nuclei and many large vacuoles, yolk granules, and other inclusions; the latter increase in number and electron density as the animal ages.	intestine	gut	WBbt:0005772
Longitudinal bands of muscle cells surrounding animal body, with one band running in each quadrant of the body, regulated contraction and relaxation of these muscles cause locomotion.	body wall musculature	body muscle	WBbt:0005813
Epidermal layer.	hypodermis	epidermis	WBbt:0005733
the feeding organ, a neuro-muscular pump in the head of the animal, used to ingest food, bacteria suspended in liquid, filter them out, grind them up and transport posteriorly into the instestine.	pharynx	esophagus	WBbt:0003681
Complement of nervous tissue (neurones, nerves, receptors and support cells) serving to detect, relay and coordinate information about an animal`s internal and external environments and to initiate and integrate its effector responses and activities.	nervous system		WBbt:0005735

1 Genes

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00004951	spc-1	K10B3.10	Caenorhabditis elegans

1 Life Stages

Remark	Definition	Other Name	Public Name	Primary Identifier
	The whole period of embryogenesis in the nematode Caenorhabditis elegans, from the formation of an egg until hatching.		embryo Ce	WBls:0000003