WormMine

WS295

Intermine data mining platform for C. elegans and related nematodes

Expression Pattern :

Pattern  Antibody staining: Transient nuclear staining in early MS lineage identical to lacZ pattern. Stable nuclear expression begins in the 2 daughters of D at the ~90 cell stage, then C and MS lineages that give rise to body wall muscle cells (bwm). The lone AB bwm appears positive after born. At pretzel stage, nuclear staining in the 6 GLR cells. Staining persists throughout postembryonic development in bwm cells, including post-embryonically born bwm. lacZ reporter gene expression: Multiple constructs with multiple lines. Transient expression in 2 MS daughters and the 4 MS granddaughters. Stable expression begins at ~90 cell stage in two daughters of D. Then on in C, MS lineages that give rise to body wall muscle precursors. At pretzel stage, hlh-1 is also expressed in the 6 GLR cells. positive hybridisation to RNA (in _situ) same as lacZ pattern except RNA appears to go away at bean stage and reappear later in embryogenesis Primary Identifier  Expr56
Remark  90 cell embryo(author) = 88-cell embryo(curator). CeMyoD :Basic Helix-loop-helix transcription factor. Related to the vertebrate MyoD family that is involved in the regulation of striated muscle cell fate.Vertebrate Homologs: Mammalian factors MyoD, MRF-4, Myf-5, myogenin.Invertebrate Homologs: Drosophila protein "Nautilus", sea urchin "SUM-1". Legacy Data: Author "Seydoux GC" "Krause MW". Date 1995-08. Function: Putative null mutation (cc450) of L. Chen and A.Fire suggests important role for CeMyoD in body wall muscle cell function and morphogenesis. CeMyoD is not required for bwm cell fate determination but is for proper bwm cell differentiation
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69 Anatomy Terms

Definition Name Synonym Primary Identifier
embryonic cell MSa   WBbt:0006086
embryonic cell MSp   WBbt:0005912
embryonic cell MSaa   WBbt:0006699
embryonic cell MSap   WBbt:0006744
embryonic cell MSpa   WBbt:0006142
embryonic cell MSpp   WBbt:0006255
embryonic cell Da   WBbt:0006512
embryonic cell Dp   WBbt:0006718
Embryonic cell of pedigree Cappppv. Cappppv lineage name: Cappppv WBbt:0006337
Embryonic cell of pedigree Capappp. Capappp lineage name: Capappp WBbt:0006333
Embryonic cell of pedigree MSppappa. MSppappa DR4 WBbt:0006318
Embryonic cell of pedigree MSapaaap. MSapaaap DL2 WBbt:0006306
Embryonic cell of pedigree Cppappa. Cppappa lineage name: Cppappa WBbt:0006378
Embryonic cell of pedigree MSappppa. MSappppa DL3 WBbt:0006362
Embryonic cell of pedigree MSpapppaa MSpapppaa lineage name: MSpapppaa WBbt:0006354
Embryonic cell of pedigree MSppaaap. MSppaaap DR2 WBbt:0006342
Embryonic cell of pedigree MSpappap. MSpappap lineage name: MSpappap WBbt:0006426
Embryonic cell of pedigree Cppappp. Cppappp lineage name: Cppappp WBbt:0006419
Embryonic cell of pedigree Cappapp. Cappapp DL24 WBbt:0006406
Embryonic cell of pedigree MSaappppp. MSaappppp lineage name: MSaappppp WBbt:0006397
Embryonic cell of pedigree Cppppaa. Cppppaa DR19 WBbt:0006452
Embryonic cell of pedigree MSppappp. MSppappp DR1 WBbt:0006450
Embryonic cell of pedigree MSpppppp. MSpppppp DR5 WBbt:0006449
Embryonic cell of pedigree Capppap. Capppap DL21 WBbt:0006429
Embryonic cell of pedigree Cppaaaa. Cppaaaa lineage name: Cppaaaa WBbt:0006511
Embryonic cell of pedigree MSaapppap. MSaapppap lineage name: MSaapppap WBbt:0006498
Embryonic cell of pedigree MSapappa. MSapappa DL4 WBbt:0006495
Embryonic cell of pedigree MSappapp. MSappapp lineage name: MSappapp WBbt:0006469
Embryonic cell of pedigree Cppppap. Cppppap DR21 WBbt:0006555
Embryonic cell of pedigree Capappa. Capappa lineage name: Capappa WBbt:0006538

1 Genes

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00001948 hlh-1 B0304.1 Caenorhabditis elegans

4 Life Stages

Remark Definition Other Name Public Name Primary Identifier
  The whole period of embryogenesis in the nematode Caenorhabditis elegans, from the formation of an egg until hatching. embryo Ce WBls:0000003
  The C. elegans life stage spanning 520-620min after first cleavage at 20 Centigrade. Cell number remains at ~560 cells, with some new cells generated and some cells go through programmed cell death. The shape of embryo is elongated and tripple fold. A stage between 2-fold embryo and fully-elongated embryo. Also called pretzel embryo or pretzel stage. 3-fold embryo Ce WBls:0000020
  The C. elegans life stage spanning 350-390min after first cleavage at 20 Centigrade. Cell number remains at ~560 cells, with some new cells generated and some cells go through programmed cell death. Emrbyo elongation started but have not formed comma shape yet. The shape of embryo looks like a lima bean. A stage right before comma embryo. Also called lima embryo or lima bean stage. bean embryo Ce WBls:0000016
  The C. elegans life stage spanning 145-150 min after first cleavage at 20 Centigrade. Contains 88 cells. 88-cell embryo Ce WBls:0000012