WormMine

WS295

Intermine data mining platform for C. elegans and related nematodes

Expression Pattern :

Pattern  A die-1::gfp reporter gene, which rescues the lsy defect, shows a dynamic expression profile with early hypodermal expression ceasing at gastrulation and then reappearing in late embryos in several putative head neurons. Using an ASE-neuron-expressed red-fluorescent-protein reporter (ceh-36prom::rfp), two of these neurons were identified as ASEL and ASER. However, expression is strongly biased towards ASEL. Besides ASE expression, consistent and strong expression of gfp from the otIs159 array is also observed in the ASH, ADF and AWC neurons. Primary Identifier  Expr3425
Remark  Reporter gene fusion type not specified. The autonomous function of die-1 in the mature ASEL neurons was corroborated by expressing the die-1 complementary DNA under the control of the promoter of the ASEL-specific gcy-7 gene. When expressed in a die-1 mutant background, three of four lines showed rescue of the lsy phenotype.
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9 Anatomy Terms

Definition Name Synonym Primary Identifier
Epidermal layer. hypodermis epidermis WBbt:0005733
one member of Amphid neurons, single ciliated endings, probably chemo-sensory; project into ring via commissure from ventral ganglion, make diverse synaptic connections in ring neuropil ASEL lineage name: ABalppppppaa WBbt:0003904
one member of Amphid neurons, single ciliated endings, probably chemo-sensory; project into ring via commissure from ventral ganglion, make diverse synaptic connections in ring neuropil ASER lineage name: ABpraaapppaa WBbt:0003903
Amphid neuron, prob. chemosensory ADFL lineage name: ABalpppppaa WBbt:0004003
Amphid neuron, prob. chemosensory ADFR lineage name: ABpraaappaa WBbt:0003999
Amphid wing cells, neurons having ciliated sheet-like sensory endings closely associated with amphid sheath AWCL lineage name: ABplpaaaaap WBbt:0003827
Amphid wing cells, neurons having ciliated sheet-like sensory endings closely associated with amphid sheath AWCR lineage name: ABprpaaaaap WBbt:0003826
one member of Amphid neurons, single ciliated endings, probably chemo-sensory; project into ring via commissure from ventral ganglion, make diverse synaptic connections in ring neuropil ASHL lineage name: ABplpaappaa WBbt:0003890
one member of Amphid neurons, single ciliated endings, probably chemo-sensory; project into ring via commissure from ventral ganglion, make diverse synaptic connections in ring neuropil ASHR lineage name: ABprpaappaa WBbt:0003889

1 Genes

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00000995 die-1 C18D1.1 Caenorhabditis elegans

0 Life Stages