WormMine

WS295

Intermine data mining platform for C. elegans and related nematodes

Expression Pattern :

Pattern  imb-2/Transportin 1 Is Asymmetrically Expressed in AWCON Neurons. imb- 2::mNG knock-in animals displayed wild-type AWC asymmetry, indicating that the tagged IMB-2::mNG fusion protein is functional. IMB-2::mNG was detected in the nucleus and around the nuclear envelope of numerous cells in the head and body during embryogenesis, larval stages, and adulthood. The broad expression pattern of imb-2 in the head is consistent with expression of vertebrate transportin 1 in multiple regions of the brain, including the olfactory bulb. IMB-2::mNG was detected in both AWC neurons in late embryogenesis during which AWC asymmetry was established and was maintained until adulthood. IMB-2::mNG was asymmetrically expressed in the left AWC neuron (AWCL) or the right AWC neuron (AWCR) in a stochastic manner. Stochastic asymmetry of imb-2 expression in AWC neurons is consistent with the random nature of AWC asymmetry. IMB-2::mNG was expressed at a significantly higher expression level in the AWCON neuron than the AWCOFF neuron in the majority of animals. Primary Identifier  Expr15718
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3 Anatomy Terms

Definition Name Synonym Primary Identifier
Amphid wing cells, neurons having ciliated sheet-like sensory endings closely associated with amphid sheath AWCL lineage name: ABplpaaaaap WBbt:0003827
Amphid wing cells, neurons having ciliated sheet-like sensory endings closely associated with amphid sheath AWCR lineage name: ABprpaaaaap WBbt:0003826
one of the two AWC neurons, stochastically determined, in which the str-2 promoter is active AWC-ON   WBbt:0005832

1 Genes

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00002076 imb-2 R06A4.4 Caenorhabditis elegans

3 Life Stages

Remark Definition Other Name Public Name Primary Identifier
  The stage that begins when a C.elegans individual is fully-developed and has reached maturity. adult Ce WBls:0000041
  The whole period of embryogenesis in the nematode Caenorhabditis elegans, from the formation of an egg until hatching. embryo Ce WBls:0000003
  A developmental life stage of the nematode Caenorhabditis elegans that occurs from egg hatching until adulthood. larva Ce WBls:0000023