WormMine: ExpressionPattern Expr11007

• Pattern: egl-18 is asymmetrically expressed in larval seam division daughters with stronger expression in the posterior seam-fated cells in which the Wnt pathway is activated. All ten seam cells in newly hatched L1 larvae showed strong egl-18 expression. After their first division, egl-18::mCherry expression was asymmetric between the daughters, with stronger expression in the posterior daughters that maintain the seam cell fate. Expression in the anterior daughter faded after division, before the hypodermal daughters moved out of the seam cell line. During the L2 stage, several seam cells undergo a symmetric expansion division, generating two seam daughters and increasing the seam cell number from 10 to 16 (Sulston and Horvitz, 1977). In the early L2, strong symmetric expression of egl-18::mCherry was seen in both seam-fated daughters of these divisions. When these seam-fated daughters underwent their subsequent L2 and L3 stage asymmetric divisions, reporter expression faded in their anterior, hypodermal-fated daughters as observed in the L1 stage. In the adult, differentiated seam cells continue to show strong expression of the egl-18::mCherry reporter as described previously (Budovskaya et al., 2008).
• Primary Identifier: Expr11007

21 Anatomy Terms

Definition	Name	Synonym	Primary Identifier
a group of hypodermal cells that lie along the apical midline of the hypodermis, at the extreme left and right sides between nose and tail	seam cell	lateral hypodermis	WBbt:0005753
Seam hypodermal cell	H0R	lineage name: ABarpapppa	WBbt:0004777
Seam hypodermal cell, postembryonic blast cell	H1L	lineage name: ABplaaappp	WBbt:0004766
Seam hypodermal cell, postembryonic blast cell	H1R	lineage name: ABarpapppp	WBbt:0004765
Seam hyopdermal cell, postemb. blast cell, L1 deirid socket	H2L	lineage name: ABarppaaap	WBbt:0004764
Seam hyopdermal cell, postemb. blast cell, L1 deirid socket	H2R	lineage name: ABarpppaap	WBbt:0004763
Seam hypodermal cell	H0L	lineage name: ABplaaappa	WBbt:0004778
Tail seam hypodermal cell, postembryonic blast cell, functions as phasmid socket in L1	TL	lineage name: ABplappppp	WBbt:0004946
Tail seam hypodermal cell, postembryonic blast cell, functions as phasmid socket in L1	TR	lineage name: ABprappppp	WBbt:0004944
Seam hypodermal cell, postembryonic blast cell	V1L	lineage name: ABarppapaa	WBbt:0004905
Seam hypodermal cell, postembryonic blast cell	V5R	lineage name: ABprapapaap	WBbt:0004876
Seam hypodermal cell, postembryonic blast cell	V6L	lineage name: ABarppappp	WBbt:0004875
Seam hypodermal cell, postembryonic blast cell	V6R	lineage name: ABarpppppp	WBbt:0004874
Seam hypodermal cell, postembryonic blast cell	V3R	lineage name: ABprappapa	WBbt:0004896
Seam hypodermal cell, postembryonic blast cell	V4L	lineage name: ABarppappa	WBbt:0004894
Seam hypodermal cell, postembryonic blast cell	V4R	lineage name: ABarpppppa	WBbt:0004892
Seam hypodermal cell, postembryonic blast cell	V5L	lineage name: ABplapapaap	WBbt:0004890
Seam hypodermal cell, postembryonic blast cell	V1R	lineage name: ABarppppaa	WBbt:0004904
Seam hypodermal cell, postembryonic blast cell	V2L	lineage name: ABarppapap	WBbt:0004902
Seam hypodermal cell, postembryonic blast cell	V2R	lineage name: ABarppppap	WBbt:0004900
Seam hypodermal cell, postembryonic blast cell	V3L	lineage name: ABplappapa	WBbt:0004898

1 Genes

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00001186	egl-18	F55A8.1	Caenorhabditis elegans

0 Life Stages