WormMine: ExpressionPattern Expr10560

• Pattern: sup-1 transcriptional fusion is expressed in a subset of C. elegans neurons and muscles. Most or all of the SUP-1-positive neurons are cholinergic, including cholinergic motor neurons in the ventral nerve cord, as well as a subset of cholinergic head neurons. Expression was also noted in the anterior sublateral (SAB) neurons, and at least a subset of the body sublateral neurons. Non-neuronal expression of sup-1 appeared to be limited to the body wall muscles.SUP-1::YFP translational fusion was expressed in cholinergic neurons and body wall muscles. Fluorescence was first observable in embryos, and persisted throughout development.
• Primary Identifier: Expr10560
• Subcellular Localization: In cholinergic neurons, SUP-1 was enriched in synaptic regions, although fluorescence was also observed in processes and cell bodies.SUP-1 fusion protein expressed in the cholinergic motor neurons of the ventral nerve cord cell bodies appeared to be restricted to the plasma membrane. In the body wall muscles, SUP- 1::YFP also appeared to be localized to the plasma membrane.

7 Anatomy Terms

Definition	Name	Synonym	Primary Identifier
a large process bundle that runs along the vental mid-line extending from the ventral region of the nerve ring.	ventral nerve cord	ventral cord	WBbt:0005829
Longitudinal bands of muscle cells surrounding animal body, with one band running in each quadrant of the body, regulated contraction and relaxation of these muscles cause locomotion.	body wall musculature	body muscle	WBbt:0005813
neuron with its cell body situated in the head, excluding the pharynx.	head neuron		WBbt:0006751
neuron that uses vesicular acetylcholine as a neurotransmitter.	cholinergic neuron	ACh neuron	WBbt:0006840
Ring interneuron, anteriorly projecting process that runs sublaterally, synapses to anterior body muscles in L1	SABD	lineage name: ABplppapaap	WBbt:0004999
Ring interneuron, anteriorly projecting process that runs sublaterally, synapses to anterior body muscles in L1	SABVL	lineage name: ABplppapaaaa	WBbt:0004998
Ring interneuron, anteriorly projecting process that runs sublaterally, synapses to anterior body muscles in L1	SABVR	lineage name: ABprppapaaaa	WBbt:0004997

1 Genes

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00012759	sup-1	Y41C4A.13	Caenorhabditis elegans

3 Life Stages

Remark	Definition	Other Name	Public Name	Primary Identifier
	The stage that begins when a C.elegans individual is fully-developed and has reached maturity.		adult Ce	WBls:0000041
	The whole period of embryogenesis in the nematode Caenorhabditis elegans, from the formation of an egg until hatching.		embryo Ce	WBls:0000003
	A developmental life stage of the nematode Caenorhabditis elegans that occurs from egg hatching until adulthood.		larva Ce	WBls:0000023