WormMine

WS295

Intermine data mining platform for C. elegans and related nematodes

Anatomy Term :

Definition  Set one type of vulval muscle. Name  vm1
Primary Identifier  WBbt:0006917 Synonym  vulval muscle, type 1

4 Children

Definition Name Synonym Primary Identifier
Vulval muscle 1, of lineage M.vlpaaapp. M.vlpaaapp lineage name: M.vlpaaapp WBbt:0004854
Vulval muscle 1, of lineage M.vlpaapaa. M.vlpaapaa lineage name: M.vlpaapaa WBbt:0004853
Vulval muscle 1, of lineage M.vrpaaapp. M.vrpaaapp lineage name: M.vrpaaapp WBbt:0004850
Vulval muscle 1, of lineage M.vrpaapaa. M.vrpaapaa lineage name: M.vrpaapaa WBbt:0004849

2 Expression Clusters

Regulated By Treatment Description Algorithm Primary Identifier
  Single-cell RNA-Seq cell group 86 expressed in: Unassigned sex-specific muscle. CellRanger, DecontX, Monocle3, Louvain algorithm. WBPaper00065623:86
  Single-cell RNA-Seq cell group 85 expressed in: vm1 (vulval muscle). CellRanger, DecontX, Monocle3, Louvain algorithm. WBPaper00065623:85

7 Expression Patterns

Remark Reporter Gene Primary Identifier Pattern Subcellular Localization
    Expr11316 Strong expression all stages: neuronal expression most prominent in young larvae (fewer neurons and weaker neuronal expression later), pharyngeal muscle, vm1, gut, occasionally body wall muscle ,>20 pairs of head neurons (non-sensory), ventral nerve cord motoneurons, about 10 neurons in tail ganglia  
    Expr9405 Expression is seen in 4 neural cells of the anterior ganglion, 8 more in the lateral/ventral ganglia, and 4-6 nuclei of the tail ganglia. Staining is also seen on sub-cellular particles in the vm1 muscles of the vulva. The neural pattern develops from L1 onwards; the vulval staining occurs L4 onwards. Expressed in nuclei. Sub-cellular localization within the body wall muscle: Dense bodies, Cytoplasm, +/- Nucleus
    Expr15937 We observed strong expression of kcnl-1 in neurons and muscles involved in egg-laying and defecation (vm1, vm2, uterine muscle, stomato-intestinal muscle, and anal depressor muscle). In addition, kcnl-1 was expressed in body-wall muscles, a few neurons in head and tail ganglia, ventral nerve cord motoneurons, and the PVD mechanosensory neuron.  
    Expr10991 elt-1 reporter gene expression was first seen around the 20-30 cell stage and was maintained during subsequent early embryogenesis in cells corresponding to hypodermal precursor cells. Just prior to morphogenesis, reporter gene expression could be seen in all the major hypodermal cell nuclei. During formation of the comma stage, embryo reporter gene expression declined in the dorsal and ventral hypodermis but remained high in the lateral seam cells. The seam-cell expression of the reporter gene continued throughout morphogenesis to the pretzel stage although at lower levels. In addition, at the threefold stage of development high levels of expression were seen in a group of cells adjacent to the pharynx in a position consistent with neuronal cells of the retrovesicular ganglion. During postembryonic development relatively low levels of expression were maintained in seam cells from the L1 to the adult stage as were high levels of ELT-1 in neuronal cells of the retrovesicular ganglion. ELT-1 expression was also clearly apparent in several different groups of neuronal cell bodies and axons; those of the ventral cord were the most prominent. Expression was also seen in several neurons in which the axon extended from the ventral cord and encircled the pharynx just in front of the posterior bulb.The reporter gene also showed postembryonic expression in sex-specific structures. In hermaphrodites, ELT-1 expression was seen in the vulval muscles (vm1 and vm2) and in males, in a subset of the lateral seam, the SET cells, that give rise to the sensory rays.  
    Expr1200166 Data from the TransgeneOme project  
    Expr10805 Expression of apx-1 was observed in both secondary vulval epithelial cells and vm1 muscle cells during the L4 stage.  
    Expr11588 arg-1::gfp is expressed in both type I vulval muscles (VM1s) and type II vulval muscles.  

0 Life Stages

1 Parents

Definition Name Synonym Primary Identifier
muscle associated with hermaphrodite vulva. vulval muscle   WBbt:0005821