WormMine: AnatomyTerm WBbt:0008448

• Definition: Embryonic cell that has the developmental potential to generate a germ cell.
• Name: germline blastomere
• Primary Identifier: WBbt:0008448

5 Children

Definition	Name	Synonym	Primary Identifier
Single cell zygote	P0	lineage name: Z	WBbt:0004422
embryonic founder cell	Psub3	lineage name: P0.ppp	WBbt:0006875
embryonic founder cell	Psub1	lineage name: P0.p	WBbt:0006874
embryonic founder cell	Psub2	lineage name: P0.pp	WBbt:0006873
Embryonic founder cell of germ line	Psub4	lineage name: P0.pppp	WBbt:0004421

0 Expression Clusters

5 Expression Patterns

• Primary Identifier: Expr16099
• Subcellular Localization: In germline progenitor zone nuclei, CHK-2 is located inside the nucleus and PPM-1.D and CHK-2 strongly colocalize at the nuclear periphery.

• Primary Identifier: Expr13393
• Pattern: GFP::3xFLAG::MEG-1 is detected in the -1 to -3 oocytes in the wild-type background. The expression of GFP::3xFLAG::MEG-1 increases after meiotic maturation and fertilization . In embryos, GFP::3xFLAG::MEG-1 localized to P granules and accumulated to maximal levels in germline blastomeres in the wild-type background.

• Primary Identifier: Expr11853
• Pattern: VBH-1 antibody staining showed the same localization in oocytes and embryos as observed with the VBH-1:GFP fusion (Expr11852). VBH-1 was observed throughout both the hermaphrodite and male gonad. In the male gonad, VBH-1 was observed in primary and secondary spermatocytes but not detected in mature sperm.
• Subcellular Localization: VBH-1 was expressed in P granules throughout the gonad, and also diffusely in the cytoplasm. VBH-1, however, was not detected in the P-body-like particles.

• Primary Identifier: Expr16098
• Subcellular Localization: In germline progenitor zone nuclei, CHK-2 is located inside the nucleus and PPM-1.D and CHK-2 strongly colocalize at the nuclear periphery.

• Primary Identifier: Expr11852
• Pattern: Transgenic animals showed VBH-1:GFP localization in the cytoplasm of both somatic and germline blastomeres during embryogenesis and in oocytes.
• Subcellular Localization: VBH-1:GFP was observed in foci within the germline and co-localized with the P granule component PGL-1. VBH-1 localization was not consistently observed in every P granule, particularly during oogenesis, and on occasion we observed that PGL-1 and VBH-1 overlap only partially.

0 Life Stages

1 Parents

Definition	Name	Synonym	Primary Identifier
cell that exists in and is part of an embryo.	embryonic cell		WBbt:0007028