WormMine: ExpressionPattern Expr696

• Pattern: Expression begins at midpoint of the animal and continues to the posterior intestinal cells. GFP detected in all larval stages but most strongly from late L1 to L4. Strongly detected in posterior 8 intestinal cells, late L1 just prior to their division near the end of L1. No expression observed in anterior cells. GFP detected in intestinal cells after L1 although only in some of the divided binucleated posterior intestinal cells. Expression also detected in many neurons during all larval stages (CEPDR and CEPVR). Expression observed in posterior pharyngeal bulb muscle cells and ventral cord motorneurons in all larval stages, as well as in several hypodermal cells and body wall muscles. Expression detected in Z1 and Z4 cells in L1 larva but not in their daughters. 8 posterior intestinal cells at late L1. posterior pharyngeal bulb muscle cells. CEPDR, CEPVR at L1-L4. Hypodermal cells at L1-L4. Z1 and Z4 at L1. ventral cord motorneurons at L1-L4. Body wall muscles. Hypodermis at L1-L4.
• Primary Identifier: Expr696
• Remark: Reporter gene fusion type not specified. This information was extracted from published material (Archana Sharma-Oates, Andrew Mounsey and Ian A. Hope). mdl-1 coexpressed with mxl-1 in posterior intestinal cells.

10 Anatomy Terms

Definition	Name	Synonym	Primary Identifier
neuron with cell body associated with the ventral nerve cord.	ventral cord neuron	ventral cord motoneuron	WBbt:0005300
A chain of very large cuboidal cells forming a wide central lumen in which food arrives from the posterior pharynx, is digested, and from which waste products proceed to the rectum. Intestinal rings form in groups of two and four cells surrounding the common lumen; thus the epithelium is only one cell deep at any point, with neighboring cells firmly secured to their neighbors by apical adherens junctions. These cells have very large nuclei and many large vacuoles, yolk granules, and other inclusions; the latter increase in number and electron density as the animal ages.	intestine	gut	WBbt:0005772
Epidermal layer.	hypodermis	epidermis	WBbt:0005733
type of cells that make up muscle layers in the pharynx.	pharyngeal muscle cell		WBbt:0005451
Longitudinal bands of muscle cells surrounding animal body, with one band running in each quadrant of the body, regulated contraction and relaxation of these muscles cause locomotion.	body wall musculature	body muscle	WBbt:0005813
Major cell type of nervous tissue, specialized for transmission of information in the form of patterns of impulses.	neuron	neurone	WBbt:0003679
Cephalic neurons, contain dopamine	CEPVR	lineage name: ABprpaappppa	WBbt:0004931
Cephalic neurons, contain dopamine	CEPDR	lineage name: ABarpapaappa	WBbt:0004937
Somatic gonad precursor cell	Z1	lineage name: MSpppaap	WBbt:0004577
Somatic gonad precursor cell	Z4	lineage name: MSappaap	WBbt:0004574

1 Genes

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00003163	mdl-1	R03E9.1	Caenorhabditis elegans

4 Life Stages

Remark	Definition	Other Name	Public Name	Primary Identifier
	The second stage larva. At 25 Centigrade, it ranges 25.5-32.5 hours after fertilization, 11.5-18.5 hours after hatch.		L2 larva Ce	WBls:0000027
	The fourth stage larva. At 25 Centigrade, it ranges 40-49.5 hours after fertilization, 26-35.5 hours after hatch.		L4 larva Ce	WBls:0000038
	The first stage larva. At 25 Centigrade, it ranges 14-25.5 hours after fertilization, 0-11.5 hours after hatch.		L1 larva Ce	WBls:0000024
	The third stage larva. At 25 Centigrade, it ranges 32.5-40 hours after fertilization, 18.5-26 hours after hatch.		L3 larva Ce	WBls:0000035