WormMine: ExpressionPattern Expr8631

• Pattern: CRP-1::GFP fusion protein was first expressed in pharyngeal cells at the early comma stage of embryogenesis. At the twofold stage, CRP-1 was also detected in the rectum and later, at the 3-fold stage throughout the entire digestive tract. After hatching, CRP-1 expression was extended to the head and tail support cells and to the excretory cell. This expression pattern was maintained throughout larval stages except in dauer larvae where CRP-1 expression was restricted to the excretory system. In young adult, CRP-1::GFP expression decreased in the pharynx and appeared in the vulval epithelium. CRP-1 expression in intestinal and rectal valve, in intestinal cells, in head and tail support cells, in excretory cell, and in vulval and rectal epithelia was then maintained throughout adulthood in both males and hermaphrodites.CRP-1 was expressed exclusively in a subset of epithelial cells and myoepithelial cells (pharyngal muscles). In addition, CRP-1 expression was detectable after epithelial morphogenesis, except in the pharynx muscle where its expression was detectable at very early stage of pharynx development.
• Primary Identifier: Expr8631
• Remark: Picture: Fig 6.

7 Anatomy Terms

Definition	Name	Synonym	Primary Identifier
An interfacial epithelial cell which forms a distal cap on a sheath cell to bind the sheath of a sensillum to the neighboring hypodermis, via adherens junctions. There is often a narrow opening through the socket from the exterior into the sheath channel, allowing ciliated dendrites to be exposed to the external environment. The socket cell functions similarly to a glial cell.	socket cell		WBbt:0005750
A chain of very large cuboidal cells forming a wide central lumen in which food arrives from the posterior pharynx, is digested, and from which waste products proceed to the rectum. Intestinal rings form in groups of two and four cells surrounding the common lumen; thus the epithelium is only one cell deep at any point, with neighboring cells firmly secured to their neighbors by apical adherens junctions. These cells have very large nuclei and many large vacuoles, yolk granules, and other inclusions; the latter increase in number and electron density as the animal ages.	intestine	gut	WBbt:0005772
female genital.	vulva		WBbt:0006748
A group of six equivalent cells forms a tightly constructed `valve` that links the posterior bulb of the pharynx to the anterior four cells of the intestine. These six cells comprise a small epithelial channel with a cuticular lining in continuity with the pharyngeal cuticle and link the lumen of the pharynx to the large lumen of the anterior intestine.	pharyngeal-intestinal valve	cardia	WBbt:0005767
the feeding organ, a neuro-muscular pump in the head of the animal, used to ingest food, bacteria suspended in liquid, filter them out, grind them up and transport posteriorly into the instestine.	pharynx	esophagus	WBbt:0003681
H-shaped cell associated with the excretory system, largest cell in C. elegans.	excretory cell	excretory canal cell	WBbt:0005812
epithelium connecting intestine and anus.	rectal epithelium		WBbt:0005800

1 Genes

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00012532	crp-1	Y32F6B.3	Caenorhabditis elegans

0 Life Stages