WormMine: ExpressionPattern Expr9193

• Pattern: Ins-6 expression is rare in non-neuronal tissues and restricted to the ASI neurons of well-fed larvae and adults. This is different from the previously described expression of ins-6 in many neurons (Pierce et al., 2001), including ASI, which was determined with a gfp or an mCherry transcriptional reporter fused only to the ins-6 upstream sequences. This suggests that sequences downstream of ins-6 contain element(s) that repress its expression in other cells. The switch into dauer arrest shifted the transcription of ins-6p::mCherry from ASI to ASJ. In addition, as the animals started to exit from dauer, ASJ expression of ins-6p::mCherry appeared to become stronger in response to the improved environment. The activation of ins-6 in the ASJ was also seen in worms carrying a transcriptional reporter fused only to the ins-6 upstream sequences.
• Primary Identifier: Expr9193

4 Anatomy Terms

Definition	Name	Synonym	Primary Identifier
one member of Amphid neurons, single ciliated endings, probably chemo-sensory; project into ring via commissure from ventral ganglion, make diverse synaptic connections in ring neuropil	ASIR	lineage name: ABpraapapppa	WBbt:0003887
one member of amphid neurons, single ciliated ending, probably chemo-sensory; project into ring via commissure from ventral ganglion, make diverse synaptic connections in ring neuropil	ASIL	lineage name: ABplaapapppa	WBbt:0003888
one member of Amphid neurons, single ciliated endings, probably chemo-sensory; project into ring via commissure from ventral ganglion, make diverse synaptic connections in ring neuropil	ASJL	lineage name: ABalpppppppa	WBbt:0003886
one member of Amphid neurons, single ciliated endings, probably chemo-sensory; project into ring via commissure from ventral ganglion, make diverse synaptic connections in ring neuropil	ASJR	lineage name: ABpraaappppa	WBbt:0003885

1 Genes

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00002089	ins-6	ZK84.6	Caenorhabditis elegans

6 Life Stages

Remark	Definition	Other Name	Public Name	Primary Identifier
	The second stage larva. At 25 Centigrade, it ranges 25.5-32.5 hours after fertilization, 11.5-18.5 hours after hatch.		L2 larva Ce	WBls:0000027
	The fourth stage larva. At 25 Centigrade, it ranges 40-49.5 hours after fertilization, 26-35.5 hours after hatch.		L4 larva Ce	WBls:0000038
	The first stage larva. At 25 Centigrade, it ranges 14-25.5 hours after fertilization, 0-11.5 hours after hatch.		L1 larva Ce	WBls:0000024
	The stage that begins when a C.elegans individual is fully-developed and has reached maturity.		adult Ce	WBls:0000041
	The third stage larva. At 25 Centigrade, it ranges 32.5-40 hours after fertilization, 18.5-26 hours after hatch.		L3 larva Ce	WBls:0000035
	A third stage larva specialized for dispersal and long term survival.		dauer larva Ce	WBls:0000032