WormMine: ExpressionPattern Expr8872

• Pattern: Both promoters drove expression predominantly in the neurons of the ventral cord from L1 larvae to adults. These neurons were determined to be cholinergic motor neurons of the VA, VB, DA, and DB classes, and not the AS and VC classes. GFP expression driven by the longer acr-2 promoter was frequently seen in the PVQ and DVC neurons in the tail and was infrequently observed in a few head neurons. Coexpression with reporter genes for GABAergic neurons and interneurons confirmed that the acr-2 transcriptional reporters were not expressed in the ventral cord GABAergic motor neurons or in the interneurons expressing glr-1 or nmr-1.
• Primary Identifier: Expr8872
• Remark: Picture: Figure 3A, 3B.

7 Anatomy Terms

Definition	Name	Synonym	Primary Identifier
Neuron class of eleven motoneurons, distributed along the ventral cord, which innervate ventral body muscles.	VB neuron		WBbt:0005336
Neuron class of nine ventral cord motor neuron, innervates dorsal muscle.	DA neuron		WBbt:0005278
Neuron class of seven motoneurons that innervate dorsal muscles and have cell bodies in the ventral cord.	DB neuron		WBbt:0005274
Neuron class of twelve motoneurons, distributed along the ventral cord, which innervate ventral body muscles.	VA neuron		WBbt:0005339
Interneuron, projects along ventral cord to ring	PVQL	lineage name: ABplapppaaa	WBbt:0004076
Interneuron, projects along ventral cord to ring	PVQR	lineage name: ABprapppaaa	WBbt:0004074
Neuron class of one ring interneuron, cell body in dorsorectal ganglion.	DVC	lineage name: Caapaa	WBbt:0004821

1 Genes

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00000042	acr-2	K11G12.2	Caenorhabditis elegans

5 Life Stages

Remark	Definition	Other Name	Public Name	Primary Identifier
	The second stage larva. At 25 Centigrade, it ranges 25.5-32.5 hours after fertilization, 11.5-18.5 hours after hatch.		L2 larva Ce	WBls:0000027
	The fourth stage larva. At 25 Centigrade, it ranges 40-49.5 hours after fertilization, 26-35.5 hours after hatch.		L4 larva Ce	WBls:0000038
	The first stage larva. At 25 Centigrade, it ranges 14-25.5 hours after fertilization, 0-11.5 hours after hatch.		L1 larva Ce	WBls:0000024
	The stage that begins when a C.elegans individual is fully-developed and has reached maturity.		adult Ce	WBls:0000041
	The third stage larva. At 25 Centigrade, it ranges 32.5-40 hours after fertilization, 18.5-26 hours after hatch.		L3 larva Ce	WBls:0000035