WormMine: ExpressionPattern Expr1156

• Pattern: Initially expressed during mid-embryogenesis, primarily in postproliferative hypodermal cells and neurons in the head, ventral cord and tail. This expression fades during morphogenesis so that when the larvae hatch expression is seen primarily in lateral hypodermal cells known as seam cells. Common sites of expression included the P cells and their descendents, lateral seam cells, and somatic gonad and vulva. Expression in the P lineage, whose descendents give rise to numerous ventral cord neurons, often disappeared once proliferation of the lineage was complete whereas expression in the seam cells and somatic gonad often persisted. cdk-4::GFP was biased towards the uterine cells with minor spemathecal cell expression. The cdk-4::GFP reporter gene was also expressed at high levels throughout the intestine.
• Primary Identifier: Expr1156
• Remark: mid-embryogenesis (author) = elongating embryo (wjc)

8 Anatomy Terms

Definition	Name	Synonym	Primary Identifier
neuron with cell body associated with the ventral nerve cord.	ventral cord neuron	ventral cord motoneuron	WBbt:0005300
A chain of very large cuboidal cells forming a wide central lumen in which food arrives from the posterior pharynx, is digested, and from which waste products proceed to the rectum. Intestinal rings form in groups of two and four cells surrounding the common lumen; thus the epithelium is only one cell deep at any point, with neighboring cells firmly secured to their neighbors by apical adherens junctions. These cells have very large nuclei and many large vacuoles, yolk granules, and other inclusions; the latter increase in number and electron density as the animal ages.	intestine	gut	WBbt:0005772
female genital.	vulva		WBbt:0006748
an accordion-like tube that contains sperm and is the site of oocyte fertilization.	spermatheca		WBbt:0005319
neuron with its cell body situated in the head, excluding the pharynx.	head neuron		WBbt:0006751
neuron with its cell body situated in the tail, posterior to rectum.	tail neuron		WBbt:0006759
organ producing either sperm or ova.	gonad		WBbt:0005175
toroidal epithelial cell that make up the bulk of the uterus, four cells anterior and four cells posterior to the vulva.	uterine toroidal epithelial cell	ut cell	WBbt:0006784

1 Genes

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00000406	cdk-4	F18H3.5	Caenorhabditis elegans

3 Life Stages

Remark	Definition	Other Name	Public Name	Primary Identifier
	The first stage larva. At 25 Centigrade, it ranges 14-25.5 hours after fertilization, 0-11.5 hours after hatch.		L1 larva Ce	WBls:0000024
	The C. elegans life stage spanning 620-800min(hatch) after first cleavage at 20 Centigrade. Cell number remains at ~560 cells, with some new cells generated and some cells go through programmed cell death. A stage after elongation is over. The last stage of embryogenesis. Also called pre-hatched embryo, late embryo or morphogenetic embryo.		fully-elongated embryo Ce	WBls:0000021
	The C. elegans life stage spanning 350-620min after first cleavage at 20 Centigrade. Cell number remains at ~560 cells, with some new cells generated and some cells go through programmed cell death. The stage that embryo starts elongation until elongation is over.		elongating embryo Ce	WBls:0000015