WormMine: ExpressionPattern Expr14803

• Pattern: The expression patterns of functional translation reporters for the autophagy genes lgg-1, atg-18, epg-4, epg-5 and epg-9 were analyzed. These reporters were expressed in almost all cells at the embryonic stages. At the larval and adult stages, they were also widely distributed, including in hypodermis, body wall muscles, intestinal cells and cells in the head and tail regions. The intensity of the GFP signal, however, varied in different cell types. For example, levels of EPG-9::GFP were stronger in neurons than in hypodermis, intestine and muscle at the post-embryonic stages, while EPG-4::GFP was expressed more in the intestine than in muscle and hypoder-mal cells at the L4 larval stage. The expression patterns of functional translation reporters for the autophagy genes lgg-1, atg-18, epg-4, epg-5 and epg-9 were analyzed. These reporters were expressed in almost all cells at the embryonic stages. At the larval and adult stages, they were also widely distributed, including in hypodermis, body wall muscles, intestinal cells and cells in the head and tail regions. The intensity of the GFP signal, however, varied in different cell types. For example, levels of EPG-9::GFP were stronger in neurons than in hypodermis, intestine and muscle at the post-embryonic stages, while EPG-4::GFP was expressed more in the intestine than in muscle and hypodermal cells at the L4 larval stage.
• Primary Identifier: Expr14803

6 Anatomy Terms

Definition	Name	Synonym	Primary Identifier
A chain of very large cuboidal cells forming a wide central lumen in which food arrives from the posterior pharynx, is digested, and from which waste products proceed to the rectum. Intestinal rings form in groups of two and four cells surrounding the common lumen; thus the epithelium is only one cell deep at any point, with neighboring cells firmly secured to their neighbors by apical adherens junctions. These cells have very large nuclei and many large vacuoles, yolk granules, and other inclusions; the latter increase in number and electron density as the animal ages.	intestine	gut	WBbt:0005772
Epidermal layer.	hypodermis	epidermis	WBbt:0005733
Longitudinal bands of muscle cells surrounding animal body, with one band running in each quadrant of the body, regulated contraction and relaxation of these muscles cause locomotion.	body wall musculature	body muscle	WBbt:0005813
a cellular object that consists of subcellular components, expresses genes or functions.	Cell	Cell type	WBbt:0004017
posterior region, from rectum to the end	tail		WBbt:0005741
anterior-most body region containing the pharynx.	head		WBbt:0005739

1 Genes

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00018294	atg-18	F41E6.13	Caenorhabditis elegans

3 Life Stages

Remark	Definition	Other Name	Public Name	Primary Identifier
	The stage that begins when a C.elegans individual is fully-developed and has reached maturity.		adult Ce	WBls:0000041
	The whole period of embryogenesis in the nematode Caenorhabditis elegans, from the formation of an egg until hatching.		embryo Ce	WBls:0000003
	A developmental life stage of the nematode Caenorhabditis elegans that occurs from egg hatching until adulthood.		larva Ce	WBls:0000023