WormMine: ExpressionPattern Expr3421

• Pattern: The HIM-17::GFP fusion protein is strongly expressed in the germline and localizes to virtually all germline nuclei in L4 larvae and adult hermaphrodites and males. After fertilization, HIM-17::GFP is detected at low levels in early embryos until about the 16-cell stage.
• Primary Identifier: Expr3421
• Subcellular Localization: In premeiotic and early prophase nuclei up to and including the pachytene stage, HIM-17::GFP is concentrated on DAPI-stained chromatin. As nuclei exit pachytene and progress through diplotene into the diakinesis stage, HIM-17::GFP remains concentrated in the nucleus but is no longer restricted to chromatin.

1 Anatomy Terms

Definition	Name	Synonym	Primary Identifier
cell line which early in development becomes differentiated from the remaining somatic cell line, and alone has the potential to undergo meiosis and form gametes.	germ line	germline	WBbt:0005784

1 Genes

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00001874	him-17	T09E8.2	Caenorhabditis elegans

3 Life Stages

Remark	Definition	Other Name	Public Name	Primary Identifier
	The fourth stage larva. At 25 Centigrade, it ranges 40-49.5 hours after fertilization, 26-35.5 hours after hatch.		L4 larva Ce	WBls:0000038
	The stage that begins when a C.elegans individual is fully-developed and has reached maturity.		adult Ce	WBls:0000041
	The C. elegans life stage spanning 0-100min after first cleavage at 20 Centigrade. Proliferate from 1 cell to 28 cells. From first cleavage until the start of gastrulation.		blastula embryo Ce	WBls:0000005