WormMine: ExpressionPattern Expr579

• Pattern: PAR-1 is found in the cortex of germ line cells in the whole adult gonad. In early embryos, cortical PAR-2 expression continues in P0, P1, P2, P3 and P4 (the cells of germline lineage), fades in Z2 and Z3. In all but P4, PAR-1 exhibits an asymmetric distribution.
• Primary Identifier: Expr579
• Remark: Antibodies against the amino and carboxy termini gave the same results. early embryo(author) = blastula + gastrulating embryo(curator).
• Subcellular Localization: In the distal gonad, PAR-2 staining is strongest at septa between nuclei. In the proximal gonad, PAR-2 is found uniformly in the periphery. PAR-2 is associated with the cortical cytoskeleton. PAR-2 becomes localized to the posterior cortex in P0 through P3. During the symmetrical division of P4, PAR-2 is uniformly distributed at the cortex so that both Z2 and Z3 initially show PAR-2.

9 Anatomy Terms

Definition	Name	Synonym	Primary Identifier
cell line which early in development becomes differentiated from the remaining somatic cell line, and alone has the potential to undergo meiosis and form gametes.	germ line	germline	WBbt:0005784
a female haploid germ cell.	oocyte	ovum	WBbt:0006797
Single cell zygote	P0	lineage name: Z	WBbt:0004422
embryonic founder cell	Psub3	lineage name: P0.ppp	WBbt:0006875
embryonic founder cell	Psub1	lineage name: P0.p	WBbt:0006874
embryonic founder cell	Psub2	lineage name: P0.pp	WBbt:0006873
Embryonic founder cell of germ line	Psub4	lineage name: P0.pppp	WBbt:0004421
Germ line precursor cell	Z3	lineage name: P4.a	WBbt:0004575
Germ line precursor cell	Z2	lineage name: P4.p	WBbt:0004576

1 Genes

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00003917	par-2	F58B6.3	Caenorhabditis elegans

3 Life Stages

Remark	Definition	Other Name	Public Name	Primary Identifier
	The stage that begins when a C.elegans individual is fully-developed and has reached maturity.		adult Ce	WBls:0000041
	The C. elegans life stage spanning 100-290min after first cleavage at 20 Centigrade. Proliferate from 28 cells to 421 cells. Referring to the whole period of gastrulation.		gastrulating embryo Ce	WBls:0000010
	The C. elegans life stage spanning 0-100min after first cleavage at 20 Centigrade. Proliferate from 1 cell to 28 cells. From first cleavage until the start of gastrulation.		blastula embryo Ce	WBls:0000005