WormMine: ExpressionPattern Expr2691

• Pattern: Strong expression of the UNC-59 septin-GFP chimeras was observed in distal tip cells. UNC-59::GFP expression was evident primarily during the fourth larval stage and in young adults. UNC-59::GFP was expressed in the ventral cord neurons of larvae late in the first larval stage. Postembryonic neuronal expression of UNC-59::GFP was also quite specific for each developmental stage; generally, neuronal expression was seen for a particular neuron at only one developmental stage, and frequently only for part of the stage. Expression was not observed in any other tissues.
• Primary Identifier: Expr2691
• Subcellular Localization: UNC-59::GFP was often observed in processes and commissures without being able to trace the process to a neuronal cell body, suggesting that UNC-59::GFP expression could be quite transient. GFP were excluded from the distal tip cell nuclei, and in late L4 larvae and young adults, GFP appeared as fine puncta in the distal tip cell processes.

3 Anatomy Terms

Definition	Name	Synonym	Primary Identifier
neuron with cell body associated with the ventral nerve cord.	ventral cord neuron	ventral cord motoneuron	WBbt:0005300
Posterior distal tip cell, inhibit meiosis in neighbouring germ cells, lead gonad during morphogenesis, herm gonad	posterior distal tip cell	gon herm dtc P	WBbt:0004506
Anterior distal tip cell, inhibit meiosis in neighbouring germ cells, lead gonad during morphogenesis, herm gonad	anterior distal tip cell	gon herm dtc A	WBbt:0004520

1 Genes

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00006793	unc-59	W09C5.2	Caenorhabditis elegans

5 Life Stages

Remark	Definition	Other Name	Public Name	Primary Identifier
	The second stage larva. At 25 Centigrade, it ranges 25.5-32.5 hours after fertilization, 11.5-18.5 hours after hatch.		L2 larva Ce	WBls:0000027
	The fourth stage larva. At 25 Centigrade, it ranges 40-49.5 hours after fertilization, 26-35.5 hours after hatch.		L4 larva Ce	WBls:0000038
	The first stage larva. At 25 Centigrade, it ranges 14-25.5 hours after fertilization, 0-11.5 hours after hatch.		L1 larva Ce	WBls:0000024
	The stage that begins when a C.elegans individual is fully-developed and has reached maturity.		adult Ce	WBls:0000041
	The third stage larva. At 25 Centigrade, it ranges 32.5-40 hours after fertilization, 18.5-26 hours after hatch.		L3 larva Ce	WBls:0000035