WormMine: LifeStage WBls:0000069

• Definition: At 20 Centigrade: 4-7 days after L4-adult molt. 7-10 days after first cleavage.
• Primary Identifier: WBls:0000069
• Public Name: 4-7 days post-L4 adult hermaphrodite Ce

0 Anatomy Terms

2 Contained In

Remark	Definition	Other Name	Public Name	Primary Identifier
	The stage after an hermaphrodite animal is fully-developed and reaches maturity.		adult hermaphrodite Ce	WBls:0000057
	A C. elegans life stage that occurs during the adult life stage		C. elegans life stage occurring during adulthood	WBls:0000816

1 Expression Clusters

Regulated By Treatment	Description	Algorithm	Primary Identifier
	Genes with dynamic regulation pattern in signaling pathways during aging, based on re-analysis of microarray datasets.	The approaches of Gene Set Enrichment Analysis (GSEA) were performed using Category package in version 2.6.0 of Bioconductor to identify the significantly enriched pathways and genes in both above two subsets. In this analysis, the gene sets with less than 10 genes were excluded. The t-statistic mean of the genes was computed in each KEGG (Kyoto Encyclopedia of Genes and Genomes) pathway. Using a permutation test with 1000 times, the cutoff of significance level p value was set as 0.01 for the most significant pathways related to aging. Accordingly, the significant pathways and genes were then identified under the comparison between different time points, including from L4 to D6 and from D6 to D15.	WBPaper00045140:aging_dynamic_regulation

4 Expression Patterns

• Primary Identifier: Expr13553
• Pattern: SET-18::GFP was specifically distributed in pharyngeal and body wall muscles. Muscle-specific expression of SET-18::GFP was gradually increased from day 3 to day 11.

• Primary Identifier: Expr3844
• Remark: Reporter gene fusion type not specified.
• Pattern: LIN-14::GFP in the lin-14(n179ts); maEx166 strain continues to be expressed in cells of the head (until days 18) and tail (until days 16) of the aging adult.

• Primary Identifier: Expr11969
• Pattern: mir-228::GFP expression increases during early adulthood, reaches a peak, and then begins to slowly decrease in mid to late adulthood.

• Primary Identifier: Expr3845
• Pattern: lin-4::GFP in the zaIs1 strain continues to be widely expressed in the aging adult.

1 Followed By

Remark	Definition	Other Name	Public Name	Primary Identifier
	At 20 Centigrade: 7-10 days after L4-adult molt. 10-13 days after first cleavage.		7-10 days post-L4 adult hermaphrodite Ce	WBls:0000070

1 Preceded By

Remark	Definition	Other Name	Public Name	Primary Identifier
	At 20 Centigrade: 5-6 days after L4-adult molt. 8-9 days after first cleavage.		5-days post-L4 adult hermaphrodite Ce	WBls:0000068

0 Sub Stages