WormMine: ExpressionCluster WBPaper00037950:dopaminergic-neurons

Definition	Name	Synonym	Primary Identifier
Neuron that uses dopamine (DA) as a neurotransmitter.	dopaminergic neuron		WBbt:0006746

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00000059	acr-20	R06A4.10	Caenorhabditis elegans
WBGene00000135	amt-3	M195.3	Caenorhabditis elegans
WBGene00000174	aqp-6	C32C4.2	Caenorhabditis elegans
WBGene00000239	bas-1	C05D2.4	Caenorhabditis elegans
WBGene00000244	bbs-8	T25F10.5	Caenorhabditis elegans
WBGene00000284	cah-6	T28F2.3	Caenorhabditis elegans
WBGene00000295	cat-1	W01C8.6	Caenorhabditis elegans
WBGene00000296	cat-2	B0432.5	Caenorhabditis elegans
WBGene00000298	cat-4	F32G8.6	Caenorhabditis elegans
WBGene00000403	casy-1	B0034.3	Caenorhabditis elegans
WBGene00000463	ceh-43	C28A5.4	Caenorhabditis elegans
WBGene00000484	che-2	F38G1.1	Caenorhabditis elegans
WBGene00000490	che-11	C27A7.4	Caenorhabditis elegans
WBGene00000492	che-13	F59C6.7	Caenorhabditis elegans
WBGene00000914	daf-19	F33H1.1	Caenorhabditis elegans
WBGene00000934	dat-1	T23G5.5	Caenorhabditis elegans
WBGene00000995	die-1	C18D1.1	Caenorhabditis elegans
WBGene00001053	dop-2	K09G1.4	Caenorhabditis elegans
WBGene00001117	dyf-1	F54C1.5	Caenorhabditis elegans
WBGene00001121	dyf-5	M04C9.5	Caenorhabditis elegans
WBGene00001127	dyf-11	C02H7.1	Caenorhabditis elegans
WBGene00001440	fkh-8	F40H3.4	Caenorhabditis elegans
WBGene00001447	flp-4	C18D1.3	Caenorhabditis elegans
WBGene00001452	flp-9	C36H8.3	Caenorhabditis elegans
WBGene00001594	glc-4	C27H5.8	Caenorhabditis elegans
WBGene00001709	grk-2	W02B3.2	Caenorhabditis elegans
WBGene00001987	hot-2	Y39B6A.48	Caenorhabditis elegans
WBGene00003232	mgl-1	ZC506.4	Caenorhabditis elegans
WBGene00003657	nhr-67	C08F8.8	Caenorhabditis elegans
WBGene00003732	nhx-4	F14B8.1	Caenorhabditis elegans

Remark	Definition	Other Name	Public Name	Primary Identifier
	The whole period of embryogenesis in the nematode Caenorhabditis elegans, from the formation of an egg until hatching.		embryo Ce	WBls:0000003
	A developmental life stage of the nematode Caenorhabditis elegans that occurs from egg hatching until adulthood.		larva Ce	WBls:0000023

Algorithm	A Mann-Whitney U test with an empirical background model and FDR correction for multiple testing was used to detect expressed transcripts (Benjamini and Hochberg 1995). Genes and TARs with an FDR <= 0.05 were reported as expressed above background. Authors detected differentially expressed transcripts using a method based on linear models. Genes and TARs were called differentially expressed if the FDR was <= 0.05 and the fold change (FC) >= 2.0. To more strictly correct for potential false-positives resulting from multiple sample comparisons, authors divided individual FDR estimates by the number of samplesor sample comparisons, respectively. This resulted in an adjusted FDR of 1.3 * 0.0001 for expression above background and of 7.4 * 0.0001 for differential expression. Authors called genes selectively enriched in a given tissue if they met the following requirements: (1) enriched expression in a given tissue (FDR <= 0.05 and FC >= 2.0), (2) fold change versus reference among the upper 40% of the positive FC range observed for this gene across all tissues, and (3) fold-change entropy among the lower 40% of the distribution observed for all genes.	Description	Genes significantly enriched (> 2x, FDR < 5%) in a particular cell-type versus a reference sample of all cells at both embryonic and larval stages.
Primary Identifier	WBPaper00037950:dopaminergic-neurons_CoreEnriched

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