WormMine: RNAi WBRNAi00085149

• WormBase ID: WBRNAi00085149
• Genotype: meg-1(vr10); PGL-1::RFP
• Phenotype Remark: meg-1(vr10) animals exposed to nos-2 RNAi and grown at 26 degrees C developed gonads devoid of germ cells; PGL-1::RFP expression, a marker of P granules, was mislocalized from the nuclear periphery and dispersed aberrantly into the cytoplasm; 57% of gonads failed to proliferate beyond the first two primordial germ cells, Z2 and Z3.

1 Organism

• Name: Caenorhabditis elegans
• Taxon Id: 6239

1 Data Sets

• WormBaseAcedbConverter

2 Inhibits Gene

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00001872	him-14	ZK1127.11	Caenorhabditis elegans
WBGene00003784	nos-2	ZK1127.1	Caenorhabditis elegans

2 Inhibits Predicted Gene

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
CDS:ZK1127.11	ZK1127.11	2529	II: 7065118-7065237
CDS:ZK1127.1	ZK1127.1	780	II: 7065674-7065754

1 Laboratories

Primary Identifier
YL

4 Phenotype

Identifier	Name	Description
WBPhenotype:0000823	germline proliferation variant	Nuclear divisions in the germ line are either expanded are reduced compared to control.
WBPhenotype:0000215	no germ line	Animals lack all germline progenitor cells, thereby resulting in the complete absence of a germline.
WBPhenotype:0000679	transgene subcellular localization variant	Any variation in the subcellular localization of a gene product produced by DNA coded for by exogenous genetic material that has been introduced into the organism compared to its expression in control animals.
WBPhenotype:0001302	P granule localization defective	The restricted localization of P granules to germ cells or germ cell precursors is altered compared to control.

0 Phenotype _ Not _ Observed

1 Reference

First Author	Title	Year	Journal	Volume	Pages	PubMed ID
						WBPaper00038112

0 Strain