WormMine: RNAi WBRNAi00069899

• WormBase ID: WBRNAi00069899
• Phenotype Remark: tlf-1 Is selectively required for early gene transcription and analysis of various reported genes here supports the hypothesis that CeTLF is selectively required to transcribe some but not all Pol II genes
• Remark: Authors monitored bulk transcription in early tlf-1(RNAi) embryos using the monoclonal antibody H5. When the transcriptional apparatus shifts from initiation to elongation, the carboxy-terminal domain (CTD) of the large subunit of Pol II becomes phosphorylated, H5 recognizes phosphoserine at position two or five within the heptamer repeat of the CTD.

1 Organism

• Name: Caenorhabditis elegans
• Taxon Id: 6239

1 Data Sets

• WormBaseAcedbConverter

1 Inhibits Gene

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00006577	tlf-1	F39H11.2	Caenorhabditis elegans

2 Inhibits Predicted Gene

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
CDS:F39H11.2b	F39H11.2b	1527	I: 8698316-8698372
CDS:F39H11.2a	F39H11.2a	1518	I: 8698316-8698372

1 Laboratories

Primary Identifier
SM

1 Phenotype

Identifier	Name	Description
WBPhenotype:0000137	mRNA levels reduced	Animals exhibit decreased levels of messenger RNA compared to control.

0 Phenotype _ Not _ Observed

1 Reference

First Author	Title	Year	Journal	Volume	Pages	PubMed ID
						WBPaper00004351

0 Strain