WormMine: RNAi WBRNAi00110237

• WormBase ID: WBRNAi00110237
• Genotype: zcIs13 [hsp-6p::GFP]; rmIs101 [rgef-1p::Q40::YFP]
• Phenotype Remark: "We predicted that the cell-non-autonomous induction of mitochondrial chaperones observed with neuronal polyQ40 expression requires one or more essential UPRmt factors. To test this hypothesis, we applied RNAi against ubl-5, dve-1, atfs-1, and clpp-1, and cco-1 to neuronal polyQ40 worms expressing hsp-6p::GFP. RNAi against dve-1, atfs-1, and clpp-1 blocked the induction of the hsp-6p::GFP reporter in peripheral tissues, while cco-1 RNAi showed robust induction (Figures 2A and 2B)."
• Remark: (Figure 2A, 2B) dve-1 RNAi. Exact sequence used for RNAi not stated by authors, Ahringer laboratory clone used for curation.

1 Organism

• Name: Caenorhabditis elegans
• Taxon Id: 6239

1 Data Sets

• WormBaseAcedbConverter

1 Inhibits Gene

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00022861	dve-1	ZK1193.5	Caenorhabditis elegans

4 Inhibits Predicted Gene

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
CDS:ZK1193.5a	ZK1193.5a	1407	X: 427687-427770
CDS:ZK1193.5c	ZK1193.5c	783	X: 427687-427770
CDS:ZK1193.5e	ZK1193.5e	1398	X: 427687-427770
CDS:ZK1193.5d	ZK1193.5d	774	X: 427687-427770

0 Laboratories

1 Phenotype

Identifier	Name	Description
WBPhenotype:0001278	transgene expression reduced	Any decrease in the intensity of expression of a gene product produced by exogenous DNA that has been introduced into the organism compared to its expression in control animals.

0 Phenotype _ Not _ Observed

1 Reference

First Author	Title	Year	Journal	Volume	Pages	PubMed ID
						WBPaper00050142

0 Strain