WormMine

WS294

Intermine data mining platform for C. elegans and related nematodes

RNAi :

WormBase ID  WBRNAi00078101 Genotype  PD4743
Phenotype Remark  Whereas 64 percent (n=76) of embryos from untreated hermaphrodites showed D+C cell expression of the reporter gene, only 9 percent (n=96) of embryos from pal-1 RNAi-treated hermaphrodites had GFP-positive cells. This demonstrates that PAL-1 is required for efficient JKL26 bodywall muscle expression in D+C lineages. Authors also show that the response of JKL26 reporters to PAL-1 activity is POP-1 dependent, either directly or indirectly. Remark  Exact sequence used for RNAi not stated by authors, spliced coding region sequence of gene (C38D4.6a.1) used for curation. PD4743 contains four copies of an enh-1 subfragment (JKL26) that was bodywall muscle specific expression, a putative PAL-1-binding site, with the pes-10 basal promoter.

1 Organism

Name Taxon Id
Caenorhabditis elegans 6239

1 Data Sets

Name URL
WormBaseAcedbConverter  

1 Inhibits Gene

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00003912 pal-1 C38D4.6 Caenorhabditis elegans

3 Inhibits Predicted Gene

WormMine ID Sequence Name Length (nt) Chromosome Location
CDS:C38D4.6a C38D4.6a 813   III: 4805211-4805253
CDS:C38D4.6c C38D4.6c 669   III: 4805211-4805253
CDS:C38D4.6b C38D4.6b 807   III: 4805211-4805253

1 Laboratories

Primary Identifier
KM

1 Phenotype

Identifier Name Description
WBPhenotype:0000717 gene expression variant Variations in the processes that convert a gene's sequence into a mature gene product or products (proteins or RNA), compared to control.

0 Phenotype _ Not _ Observed

1 Reference

First Author Title Year Journal Volume Pages PubMed ID
            WBPaper00032967

0 Strain