WormMine: Gene WBGene00007767

• WormBase Gene ID: WBGene00007767
• Gene Name: C27C7.2
• Sequence Name: C27C7.2
• Organism: Caenorhabditis elegans
• Automated Description: Is affected by ubc-9; sir-2.1; and mrps-5 based on microarray studies. Is affected by resveratrol based on microarray studies.
• Biotype: SO:0000336
• Genetic Position: :±
• Length (nt): 302

1 Organism

• Name: Caenorhabditis elegans
• Taxon Id: 6239

1 Synonyms

• Value: WBGene00007767

Genomics

0 Transcripts

Other

0 CDSs

0 RNAi Result

15 Allele

• gk962858
• gk962706
• gk963849
• gk963906
• WBVar02122758
• WBVar02121095
• WBVar02122508
• WBVar02122896
• WBVar02123346
• WBVar02121524
• gk963278
• gk962676
• WBVar02120577
• WBVar02121698
• ok3747

1 Chromosome

• WormBase ID: I
• Organism: Caenorhabditis elegans
• Length (nt): 15072434

1 Chromosome Location

• Feature . Primary Identifier: WBGene00007767
• Start: 11433121
• End: 11433422
• Strand: -1

2 Data Sets

• WormBaseAcedbConverter
• C. elegans genomic annotations (GFF3 Gene)

1 Downstream Intergenic Region

• WormBase ID: intergenic_region_chrI_11432157..11433120
• Length (nt): 964
• Chromosome Location: I: 11432157-11433120
• Organism: Caenorhabditis elegans

14 Expression Clusters

Regulated By Treatment	Description	Algorithm	Primary Identifier
	Genes found to be regulated by low-copy overexpression of sir-2.1 with p < 0.014.	N.A.	WBPaper00026929:sir-2.1_overexpression_regulated
	TGF- Dauer pathway adult transcriptional targets. Results obtained by comparing the microarray results of the dauer-constitutive mutants daf-7(e1372), daf-7(m62), and daf-1(m40) with dauer-defective mutants daf-3(mgDf90), daf-5(e1386), and daf-7(e1372);daf-3(mgDf90) double mutants at the permissive temperature, 20C, on the first day of adulthood.	SAM	WBPaper00031040:TGF-beta_adult_downregulated
	Germline-enriched and sex-biased expression profile cluster C.	hierarchical clustering	[cgc6390]:Cluster_C
	Genes found to be regulated in daf-16(mgDf50) by resveratrol treatment with p < 0.01.	N.A.	WBPaper00026929:Resveratrol_regulated_daf-16
Bacteria infection: Photorhabdus luminescens	Genes with increased expression after 24 hours of infection by P.lumniescens Fold changes shown are pathogen vs OP50.	For RNA-seq and tiling arrays, log2 fold changes between gene expression values of infected versus uninfected nematodes were calculated. For log2 fold changes > 0.00001 the values > 81.25th percentile were defined as up-regulated and for log2 fold changes < -0.00001 the values < 18.75th percentile were defined as down-regulated.	WBPaper00038438:P.lumniescens_24hr_upregulated_TilingArray
	Genome-wide analysis of developmental and sex-regulated gene expression profile.	self-organizing map	cgc4489_group_8
Drug treatment: Rhine sediment	Genes with significantly changing transcripts in C. elegans exposed to the Rhine (R) sediment.	[ANOVA, p < 0.05 without multiple sample correction, fold-change to reference sediment Danube (D) > 1.4 (up-regulated) or < 0.7 (down-regulated)].	WBPaper00033070:Rhine_downregulated
Bacteria infection: Serratia marcescens	Genes with decreased expression after 24 hours of infection by S.marcescens Fold changes shown are pathogen vs OP50.	For RNA-seq and tiling arrays, log2 fold changes between gene expression values of infected versus uninfected nematodes were calculated. For log2 fold changes > 0.00001 the values > 81.25th percentile were defined as up-regulated and for log2 fold changes < -0.00001 the values < 18.75th percentile were defined as down-regulated.	WBPaper00038438:S.marcescens_24hr_downregulated_TilingArray
	Transcripts that showed significantly increased expression in mrps-5(RNAi) comparing to in control animals.	Fold change > 4, p-value < 0.01	WBPaper00056330:mrps-5(RNAi)_upregulated
	Transcripts that showed more than 4 fold of expression in N2 comparing to in CB4856 animals.	DESeq2, fold change > 4.	WBPaper00053909:N2_vs_CB4856_upregulated
	Genes that are up or down regulated by more than 2.1 fold with the t-test p-value less than 0.01 are included in this cluster.	Genes that are regulated by more than 2.1 fold with the t-test p-value less than 0.01 are included in this cluster.	WBPaper00024393:strongly_regulated_dauer_genes
	Genes that showed significantly increased expression in ubc-9(RNAi) animals comparing to control RNAi animals.	N.A.	WBPaper00045390:ubc-9(RNAi)_upregulated
Fed by 25 mg/ml pRJ-Fr.5 (Protease-treated Royal Jelly) for 24 h beginning at the L4 stage.	Genes down regulated after fed by 25 mg/ml pRJ-Fr.5 for 24 h beginning at the L4 stage.	To identify differentially regulated genes, authors eliminated all probes with absent or marginal flags and then performed a t-test with the significance level set at p < 0.05.	WBPaper00040116:pRJ-FR.5_down_regulated
	Coexpression clique No. 53, col-128-cdh-10_9234, on the genome-wide coexpression clique map for the nematode GPL200 platform.	All available microarray datasets for the GPL200 platform (Affymetrix C. elegans Genome Array) were obtained from the GEO repository. This included 2243 individual microarray experiments. These were normalized against each other with the software RMAexpress (Bolstad, 2014). Based on these normalized values, Pearsons correlation coefficients were obtained for each probe-probe pair of the 22,620 probes represented on this array type. The resulting list of correlation coefficients was then ranked to generate the ranked coexpression database with information on each probe represented on the GPL200 platform.	WBPaper00061527:col-128-cdh-10_9234

1 Expression Patterns

• Primary Identifier: Expr1014819
• Pattern: Developmental gene expression time-course. Raw data can be downloaded from ftp://caltech.wormbase.org/pub/wormbase/datasets-published/levin2012

0 GO Annotation

0 Homologues

1 Locations

• Feature . Primary Identifier: WBGene00007767
• Start: 11433121
• End: 11433422
• Strand: -1

0 Ontology Annotations

0 Regulates Expr Cluster

1 Sequence

• Length: 302

1 Sequence Ontology Term