WormMine

WS295

Intermine data mining platform for C. elegans and related nematodes

Gene :

WormBase Gene ID  ? WBGene00045218 Gene Name  K08C9.8
Sequence Name  ? K08C9.8 Organism  Caenorhabditis elegans
Automated Description  Is affected by several genes including mut-16; pqm-1; and dpy-21 based on microarray and RNA-seq studies. Is affected by five chemicals including rotenone; multi-walled carbon nanotube; and Psoralens based on RNA-seq studies. Biotype  SO:0000336
Genetic Position  Length (nt)  ? 2045
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1 Organism

Name Taxon Id
Caenorhabditis elegans 6239

1 Synonyms

Value
WBGene00045218

Genomics

0 Transcripts

 

Other

0 CDSs

0 RNAi Result

43 Allele

Public Name
gk962858
gk962706
gk963849
gk963906
WBVar02066453
WBVar00245511
WBVar01713182
WBVar01713183
WBVar01663325
WBVar01663324
WBVar01663327
WBVar01663326
WBVar01392141
WBVar01663328
WBVar01993372
WBVar01663323
WBVar01663322
gkDf21
WBVar00157277
WBVar00157278
WBVar02001925
WBVar00157281
gk422771
gk694115
WBVar02001924
WBVar00157279
gk635458
WBVar00157280
gk808926
gk813794

1 Chromosome

WormBase ID Organism Length (nt)
I Caenorhabditis elegans 15072434  

1 Chromosome Location


Feature . Primary Identifier
Start End Strand
WBGene00045218 11493036 11495080 -1

2 Data Sets

Name URL
WormBaseAcedbConverter  
C. elegans genomic annotations (GFF3 Gene)  

1 Downstream Intergenic Region

WormBase ID Name Sequence Name Length (nt) Chromosome Location Organism
intergenic_region_chrI_11492774..11493035   262 I: 11492774-11493035 Caenorhabditis elegans

22 Expression Clusters

Regulated By Treatment Description Algorithm Primary Identifier
  Genes with increased RNA expression after 24 hours rotenone treatment EdgeR provides statistical routines for determining differential expression in digital gene expression data using a model based on the negative binomial distribution. The resulting p-values were adjusted using the Benjamini and Hochbergs approach for controlling the false discovery rate (FDR). Transcripts with an adjusted p-value smaller 0.05 were assigned as differentially expressed. WBPaper00044426:rotenone_24h_upregulated
  Transcripts that showed significantly decreased expression in eat-2(ad1116) comparing to in N2 at 3-days post L4 adult hermaphrodite animals. DESeq2(v1.14.1), fold change > 2, p-value < 0.05 WBPaper00055354:eat-2(ad1116)_downregulated
  Transcripts that showed significantly decreased expression after animals were treated with 100uM Psora and 250uM Allantoin from day 1 to day 3 adult hermaphradite. DESeq2(v1.14.1), fold change > 2, p-value < 0.05 WBPaper00055354:Psora-Allantoin_downregulated
  Transcripts that showed significantly increased expression in dpy-21(e428) comparing to in N2 during L3 stage. DESeq v1.6.3. Fold change > 1.5. WBPaper00050370:dpy-21(e428)_L3_upregulated
  Up-regulated genes (fold change > 1.5) in two CoQ-deficient clk-1 mutant strains (e2519, qm30) compared to wild types N2. Fold-changes of intensities were calculated from the arithmetic mean of gene expression values between experimental and corresponding control group. Fold change >= 1.5 was used as cut-off. WBPaper00045774:clk-1_upregulated
  Transcripts depleted in RIS neurons comparing to in all cells. edgeR 3.24.3, FDR < 0.01 WBPaper00058969:RIS_depleted
  Transcripts that showed significantly depleted expression in sensory neuron (labeled by iaIs25[Pgcy-37::GFP + unc-119(+)]) comparing to in whole worm. Fold change > 2, p-value < 0.05. WBPaper00060661:sensory-neuron_depleted
  Transcripts that showed significantly decreased expression in the germline of iff-1(RNAi) animals comparing to the germine of N2 animals applied with control vector at 15C. Statistical comparisons were made by two-tailed t-test, n=3 (each replicate contains 150 extruded germ lines from N2 wild-type worms), P < 0.01 was considered significant. WBPaper00057288:iff-1(RNAi)_downregulated_transcript
  Transcripts that showed significantly decreased expression in day 3 adult hermaphrodite comparing to in L4 larva fem-3(q20) animals. Fold change > 2, FDR < 0.05 WBPaper00064088:Day-3-adult_vs_L4_downregulated_fem-3(q20)
  Targets of endo-siRNA that showed significantly decreased expression in BFF40[meg-3(tm4259);meg-4(ax2026);mex-5::gfp::h2b::tbb-2] comparing to in SX1263[Pmex-5::gfp::h2b::tbb-2 (mjIs134 II)] dissected gonad isolated from 1-day old adult hermaphrodites. DESeq2, fold change > 2, FDR < 0.01 WBPaper00057140:meg-3(tm4259)_meg-4(ax2026)_downregulated
Heat shock: 35C for 1 hour. Transcripts that showed significantly decreased expression immediately after 1-day post L4 adult hermaphrodite endu-2(tm4977) animals were exposed to 35C for 1 hour. The DESeq2 (GalaxyVersion 2.11.40.6 + galaxy1) was used to determine differentiallyexpressed features from count tables of differential transcript abundances. log2FC > 1, FDR < 0.01. WBPaper00065749:Heat-Shock_downregulated_endu-2(tm4977)
Heat shock: 35C for 1 hour. Transcripts that showed significantly decreased expression immediately after 1-day post L4 adult hermaphrodite N2 animals were exposed to 35C for 1 hour. The DESeq2 (GalaxyVersion 2.11.40.6 + galaxy1) was used to determine differentiallyexpressed features from count tables of differential transcript abundances. log2FC > 1, FDR < 0.01. WBPaper00065749:Heat-Shock_downregulated_N2
  Transcripts that showed significantly decreased expression in CB4856 animals growing in 15mg per mL doxycycline from L1 to L4 larva stage. edgeR (version 3.24.3), fold change > 4, FDR < 0.01. WBPaper00062456:doxycycline_downregulated_CB4856_transcript
  Transcripts that showed significantly increased expression in natural variant RC301(that showed resistance towards bacteria infection) vs. natural variant DA650, after 4 hour of infection by P. aeruginosa PA14. Fold change > 2, p-value < 0.05. WBPaper00050712:RC301_vs_DA650_4h-PA_upregulated
  Transcripts that showed significantly decreased expression in pqm-1(ok485) animals after exposure to 5mM CoCl2 for 6 hours, comparing to in N2 animals with the same exposure to CoCl2. Significant differentially-expressed gene sets were identified using one or two-class SAM. WBPaper00060399:pqm-1(ok485)_downregulated_CoCl2_6hr
  Genes that showed significantly increased expression after exposure to 1mg/L MWCNTs from L1 larva to young adult. Transcripts with false discovery rate-corrected p-values < 0.05 and fold change > 2 were defined as differentially expressed. WBPaper00049377:MWCNT_upregulated
  Transcripts that showed significantly increased expression in VC222[raga-1(ok386)] comparing to in N2 at mid-L4 larva stage. DESeq2, FDR < 0.01, fold change > 2. WBPaper00057196:raga-1(ok386)_upregulated)
  Transcripts that showed significantly decreased expression in mut-16(pk710), comparing to in N2 animals. DESeq2 v. 1.22.2, adjusted p-value <= 0.05. WBPaper00059605:mut-16(pk710)_downregulated
  Transcripts that showed increased expression in smg-1(r910) and smg-1(r910) smg-2(r915) mutants comparing to in N2, and their mRNAs co-purify with SMG-2. edgeR WBPaper00053308:SMG-2_associated_NMD(-)_upregulated_ClassI
  Transcripts that showed significantly decreased expression in wdr-5(ok1417);skn-1(lax188) comparing to in skn-1(lax188) at day 2 adult stage. fold change > 2 WBPaper00058711:wdr-5(ok1417)_downregulated
Human amyloid beta peptide and pro or anti aggregating tau protein. Transcripts that showed differential expression between N2 and animals expressing human amyloid beta peptide (strain CL2355) and pro-aggregating tau (strain BR5270) or anti-aggregating tau protein (BR5271), at L4 larva stage. To identify differential gene expression, analysis was performed using CuffLinks 2.2.1 with false discovery rate corrected P values (q values) of < 0.05 and log2 (fold change) > 1 or < 1. WBPaper00053154:human-amyloid-beta_tau_regulated
  Transcripts that showed significantly decreased expression in DA116[eat-2(ad1116)] comparing to in N2. The DESeq2 package (v1.24.0) was used to identify differentially expressed genes (DEGs). Fold change > 2, FDR < 0.05. WBPaper00061040:eat-2(ad1116)_downregulated

0 Expression Patterns

0 GO Annotation

0 Homologues

1 Locations


Feature . Primary Identifier
Start End Strand
WBGene00045218 11493036 11495080 -1

0 Ontology Annotations

0 Regulates Expr Cluster

1 Sequence

Length
2045

1 Sequence Ontology Term