WormMine

WS295

Intermine data mining platform for C. elegans and related nematodes

Gene :

WormBase Gene ID  ? WBGene00015604 Gene Name  fbxa-160
Sequence Name  ? C08E3.12 Organism  Caenorhabditis elegans
Automated Description  Is affected by several genes including rsr-2; ints-5; and lin-15B based on microarray; tiling array; and RNA-seq studies. Is affected by resveratrol and copper sulfate based on microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF38/FTH, Caenorhabditis species; F-box A protein FB224; and FTH domain. Biotype  SO:0001217
Genetic Position  II :-15.1659 ±0.008771 Length (nt)  ? 766
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1 Organism

Name Taxon Id
Caenorhabditis elegans 6239

1 Synonyms

Value
WBGene00015604

Genomics

1 Transcripts

WormMine ID Sequence Name Length (nt) Chromosome Location
Transcript:C08E3.12.1 C08E3.12.1 723   II: 1623907-1624672
 

Other

1 CDSs

WormMine ID Sequence Name Length (nt) Chromosome Location
CDS:C08E3.12 C08E3.12 723   II: 1623907-1624128

1 RNAi Result

WormBase ID
WBRNAi00010444

68 Allele

Public Name
WBVar02124326
WBVar02123182
WBVar02121537
WBVar02123791
gk964317
gk963801
WBVar02122524
WBVar02120604
WBVar02121124
WBVar02124543
WBVar02120776
WBVar02121946
gk963786
WBVar02122430
WBVar02122773
WBVar02123007
WBVar00091178
WBVar02122094
WBVar00091053
WBVar01716876
WBVar01716877
WBVar01716878
WBVar01716879
WBVar01716884
WBVar01716885
WBVar01716880
WBVar01716881
WBVar01716882
WBVar01716883
WBVar01763000

1 Chromosome

WormBase ID Organism Length (nt)
II Caenorhabditis elegans 15279421  

1 Chromosome Location


Feature . Primary Identifier
Start End Strand
WBGene00015604 1623907 1624672 -1

2 Data Sets

Name URL
WormBaseAcedbConverter  
C. elegans genomic annotations (GFF3 Gene)  

1 Downstream Intergenic Region

WormBase ID Name Sequence Name Length (nt) Chromosome Location Organism
intergenic_region_chrII_1622848..1623906   1059 II: 1622848-1623906 Caenorhabditis elegans

13 Expression Clusters

Regulated By Treatment Description Algorithm Primary Identifier
  Genes that were upregulated in lin-15B(n744). For each gene in each microarray hybridization experiment, the ratio of RNA levels from the two samples was transformed into a log2 value and the mean log2 ratio was calculated. The log2 ratios were normalized by print-tip Loess normalization (Dudoit and Yang, 2002). All genes with a false discovery rate of <= 5% (q <= 0.05) (Storey and Tibshirani, 2003) and a mean fold-change ratio of >= 1.5 were selected for further analysis. WBPaper00038168:lin-15B(n744)_upregulated
Bacteria infection: Enterococcus faecalis Genes with increased expression after 24 hours of infection by E.faecalis Fold changes shown are pathogen vs OP50. For RNA-seq and tiling arrays, log2 fold changes between gene expression values of infected versus uninfected nematodes were calculated. For log2 fold changes > 0.00001 the values > 81.25th percentile were defined as up-regulated and for log2 fold changes < -0.00001 the values < 18.75th percentile were defined as down-regulated. WBPaper00038438:E.faecalis_24hr_upregulated_TilingArray
  Coexpression clique No. 203, sre-33-ZK1025.1_8337, on the genome-wide coexpression clique map for the nematode GPL200 platform. All available microarray datasets for the GPL200 platform (Affymetrix C. elegans Genome Array) were obtained from the GEO repository. This included 2243 individual microarray experiments. These were normalized against each other with the software RMAexpress (Bolstad, 2014). Based on these normalized values, Pearsons correlation coefficients were obtained for each probe-probe pair of the 22,620 probes represented on this array type. The resulting list of correlation coefficients was then ranked to generate the ranked coexpression database with information on each probe represented on the GPL200 platform. WBPaper00061527:sre-33-ZK1025.1_8337
  Genes expressed in N2. Expressed transcripts were identified on the basis of a Present call in 3 out of 4 N2 experiments as determined by Affymetrix MAS 5.0. WBPaper00025141:N2_Expressed_Genes
  Transcripts that showed significantly increased expression in ints-5(RNAi) comparing to in N2. DESeq2 and edgeR. WBPaper00056284:ints-5(RNAi)_upregulated
  Genes found to be regulated in daf-16(mgDf50) by resveratrol treatment with p < 0.01. N.A. WBPaper00026929:Resveratrol_regulated_daf-16
  Genes that showed significantly decreased expression level in rsr-2(RNAi) animals comparing to in gfp(RNAi) control. Fold change > 1.2 or < 0.8. WBPaper00042477:rsr-2(RNAi)_downregulated_TilingArray
  Genes that are up or down regulated by more than 2.1 fold with the t-test p-value less than 0.01 are included in this cluster. Genes that are regulated by more than 2.1 fold with the t-test p-value less than 0.01 are included in this cluster. WBPaper00024393:strongly_regulated_dauer_genes
  Genes that were upregulated in lin-35. For each gene in each microarray hybridization experiment, the ratio of RNA levels from the two samples was transformed into a log2 value and the mean log2 ratio was calculated. The log2 ratios were normalized by print-tip Loess normalization (Dudoit and Yang, 2002). All genes with a false discovery rate of <= 5% (q <= 0.05) (Storey and Tibshirani, 2003) and a mean fold-change ratio of >= 1.5 were selected for further analysis. WBPaper00038168:lin-35_upregulated
  Genes up-regulated greater than 2-fold by Cu2+ in wild-type animals, by comparing transcript expression levels between animals with or without Cu2+ treatment. N.A. WBPaper00042067:Cu2+_upregulated_WT
  Cu2+ up-regulated and kgb-1 mediated genes whose basal expression was decreased or not changed in kgb-1 mutants versus wild-type animals. N.A. WBPaper00042067:Cu2+_upregulated_kgb-1_top50
  Genes whose induction by Cu2+ in kgb-1 mutants was <50% of the induction seen in wild-type animals. Cu2+-mediated gene induction were compared in wild-type versus kgb-1 mutant animals. N.A. WBPaper00042067:Cu2+_upregulated_kgb-1_top66
  Transcripts that showed more than 4 fold of expression in CB4856 comparing to in N2 animals. DESeq2, fold change > 4. WBPaper00053909:N2_vs_CB4856_downregulated

2 Expression Patterns

Remark Reporter Gene Primary Identifier Pattern Subcellular Localization
    Expr1144156 Developmental gene expression time-course. Raw data can be downloaded from ftp://caltech.wormbase.org/pub/wormbase/datasets-published/hashimshony2015  
    Expr1015049 Developmental gene expression time-course. Raw data can be downloaded from ftp://caltech.wormbase.org/pub/wormbase/datasets-published/levin2012  

0 GO Annotation

0 Homologues

1 Locations


Feature . Primary Identifier
Start End Strand
WBGene00015604 1623907 1624672 -1

0 Ontology Annotations

0 Regulates Expr Cluster

1 Sequence

Length
766

1 Sequence Ontology Term