WormMine

WS295

Intermine data mining platform for C. elegans and related nematodes

Gene :

WormBase Gene ID  ? WBGene00045326 Gene Name  mir-789.2
Sequence Name  ? T28F3.10 Organism  Caenorhabditis elegans
Automated Description  Is affected by hrpk-1 and ogt-1 based on RNA-seq studies. Is affected by nicotine; sanguinarine; and silicon dioxide nanoparticle based on quantitative PCR; RNA-seq; and microarray studies. Biotype  SO:0001265
Genetic Position  IV :16.4649± Length (nt)  ? 97
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1 Organism

Name Taxon Id
Caenorhabditis elegans 6239

1 Synonyms

Value
WBGene00045326

Genomics

2 Transcripts

WormMine ID Sequence Name Length (nt) Chromosome Location
Transcript:T28F3.10b T28F3.10b 23   IV: 17309322-17309344
Transcript:T28F3.10a T28F3.10a 22   IV: 17309366-17309387
 

Other

0 CDSs

1 RNAi Result

WormBase ID
WBRNAi00036101

19 Allele

Public Name
gk964078
gk964500
gk962765
gk963590
gk962529
gk963948
gk963888
gk962795
WBVar02124494
WBVar02123843
WBVar02122008
WBVar02123118
WBVar02123266
gk750770
gk864077
WBVar01807397
WBVar01807396
WBVar01671236
WBVar01671237

1 Chromosome

WormBase ID Organism Length (nt)
IV Caenorhabditis elegans 17493829  

1 Chromosome Location


Feature . Primary Identifier
Start End Strand
WBGene00045326 17309307 17309403 -1

2 Data Sets

Name URL
WormBaseAcedbConverter  
C. elegans genomic annotations (GFF3 Gene)  

0 Downstream Intergenic Region

10 Expression Clusters

Regulated By Treatment Description Algorithm Primary Identifier
  Transcripts that showed significantly increased expression in ogt-1(ok1474) neuronal cells isolated by FACs comparing to in FACs isolated neuronal cells from wild type. DESeq2, fold change > 2, FDR < 0.05. WBPaper00066485:ogt-1(ok1474)_upregulated_neuron
  Micro RNAs that showed significantly decreased expression in day 8 adults comparing to in day 1 adults in intestine. Differentially expressed miRNAs were identified using DEGseq based on unique molecular identifier (UMI). A minimum UMI sum of 10 in 3 replicates was set as the threshold of expression. MiRNAs with more than five reads were defined as expressed. Differential expression of miRNAs was analysed by t-test (P value < 0.05 and fold-change > 1.5 or < 0.67) after Box-Cox transformation. MiRNA targets were identified by TargetScanWorm (Release 6.2) and Pearson Correlation Coefficient smaller than -0.2. WBPaper00066447:Day8_vs_Day1_downregulated_intestine
  miRNA that showed increased expression after 20mM nicotine treatment Statistical analysis was based on t-test for independent samples via SPSS. The results were further narrowed based on two criteria. Only the genes whose expression changed with a P < 0.05 and a fold change > 0.5, when compared to control, were considered as differentially expressed. Fold change was calculated as 2**(DeltaCt(treatment)-DeltaCt(control))-1. DeltaCt = Ct(miRNA)-Ct(aveMRNA). WBPaper00042480:20mM_nicotine_upregulated
Fasting for 48 hours, from 3 days post L4 to 5 days post L4. MicroRNAs that showed significantly decreased expression after 48 hours of fasting p < 0.0002, Fishers exact test. WBPaper00051247:fasting_downregulated
  Micro RNAs that showed significantly decreased expression in hrpk-1(zen17) comparing to in N2 at embryo stage. DESeq, fold change > 2, p-value <= 0.05. WBPaper00058673:hrpk-1(zen17)_downregulated_miRNA_embryo
  miRNAs that showed significantly decreased expression after 48 hour treatment in 10uM sanguinarine. Fold change > 2. WBPaper00055663:sanguinarine_downregulated
Bacteria infection: Pseudomonas aeruginosa PA14 miRNAs up regulated by Pseudomonas aeruginosa infection. N.A. WBPaper00046303:P.aeruginosa_upregulated_miRNA
  Micro RNAs that showed significantly decreased expression in day 8 adults comparing to in day 1 adults in neuron. Differentially expressed miRNAs were identified using DEGseq based on unique molecular identifier (UMI). A minimum UMI sum of 10 in 3 replicates was set as the threshold of expression. MiRNAs with more than five reads were defined as expressed. Differential expression of miRNAs was analysed by t-test (P value < 0.05 and fold-change > 1.5 or < 0.67) after Box-Cox transformation. MiRNA targets were identified by TargetScanWorm (Release 6.2) and Pearson Correlation Coefficient smaller than -0.2. WBPaper00066447:Day8_vs_Day1_downregulated_neuron
  Micro RNAs that showed significantly lower expression (log2fold > 2, padj < 0.01) in hermaphrodite gonad (somatic gonad plus germine) than in male gonad (somatic gonad plus germine). DESeq2 v1.13.8, fold change > 2, FDR < 0.01. WBPaper00056161:male_enriched_miRNA
  Micro RNAs that showed significantly increased expression in animals after 24 hour exposure to 100ug per ml silica nanoparticles (SiNPs). The random variance model (RVM)t-test was applied toidentify differentially expressed mRNAs and miRNAsbetween the SiNPs-treated group and the control group. P-value <0.05 and fold change (FC) >1.5 were considered as the threshold screening between the SiNP-treated groupand the control group. WBPaper00060100:SiNP_upregulated_miRNA

0 Expression Patterns

0 GO Annotation

0 Homologues

1 Locations


Feature . Primary Identifier
Start End Strand
WBGene00045326 17309307 17309403 -1

0 Ontology Annotations

0 Regulates Expr Cluster

1 Sequence

Length
97

1 Sequence Ontology Term