WormMine: Gene WBGene00189970

• WormBase Gene ID: WBGene00189970
• Gene Name: mir-4812
• Sequence Name: F46F2.8
• Organism: Caenorhabditis elegans
• Automated Description: Is affected by alg-5 based on RNA-seq studies. Is affected by multi-walled carbon nanotube and graphene oxide based on RNA-seq studies.
• Biotype: SO:0001265
• Genetic Position: X :22.2944±
• Length (nt): 76

1 Organism

• Name: Caenorhabditis elegans
• Taxon Id: 6239

1 Synonyms

• Value: WBGene00189970

Genomics

2 Transcripts

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
Transcript:F46F2.8b	F46F2.8b	21	X: 15242785-15242805
Transcript:F46F2.8a	F46F2.8a	22	X: 15242822-15242843

Other

0 CDSs

3 RNAi Result

• WBRNAi00031974
• WBRNAi00065088
• WBRNAi00065087

10 Allele

• gk964260
• gk962707
• gk963810
• gk963581
• WBVar01928863
• WBVar02123958
• tm11138
• WBVar02123154
• WBVar02122883
• gk615274

1 Chromosome

• WormBase ID: X
• Organism: Caenorhabditis elegans
• Length (nt): 17718942

1 Chromosome Location

• Feature . Primary Identifier: WBGene00189970
• Start: 15242774
• End: 15242849
• Strand: -1

2 Data Sets

• WormBaseAcedbConverter
• C. elegans genomic annotations (GFF3 Gene)

0 Downstream Intergenic Region

8 Expression Clusters

Regulated By Treatment	Description	Algorithm	Primary Identifier
	miRNAs that showed increased expression after exposure to graphene oxide (GO)	The dysregulated expression of miRNAs in GO-exposed nematodes was analyzed by DESeq (an R package, a powerful tool to estimate the variance and test for differential expression). The data were extracted as up- or down-regulated miRNAs according to a cutoff of 2 fold change, and were presented in the scatter diagram after normalization.	WBPaper00045209:graphene-oxide_upregulated
Bacteria infection: Pseudomonas aeruginosa PA14. 24 hours of exposure.	Small RNAs (21-26nt) that showed significantly decreased expression after L4 animals were exposed to P .aeruginosa strain PA14 for 24 hours.	DESeq2, FDR < 0.05	WBPaper00056868:P.aeruginosa_downregulated_smallRNA
	MicroRNAs that showed significantly decreased expression in alg-5(ram2), comparing to in N2.	DESeq2, Fold change > 1.5.	WBPaper00051404:alg-5(ram2)_downregulated_miRNA
	MicroRNAs that showed significantly increased expression after animals were exposed to 1 mg per liter multi-walled carbon nanotubes (MWCNTs) from L1 larva to young adult.	DESeq, cut-off of 2-fold change.	WBPaper00045019:MWCNT_upregulated
	MicroRNAs that showed significantly decreased expression in alg-5(tm1163), comparing to in N2.	DESeq2, Fold change > 1.5.	WBPaper00051404:alg-5(tm1163)_downregulated_miRNA
Heat Shock: 35C 4 hours at L4 larva stage.	Micro RNAs that showed significantly decreased expression after L4 larva N2 animals were heat stressed at 35C for 4 hours	DESeq2	WBPaper00057154:HeatShock_downregulated_miRNA
Fasting for 48 hours, from 3 days post L4 to 5 days post L4.	MicroRNAs that showed significantly increased expression after 48 hours of fasting	p < 0.0002, Fishers exact test.	WBPaper00051247:fasting_upregulated
Fungus: C. albicans	miRNAs that showed significantly decreased expression after 4 hours of infection by fungus C.albicans at 25 C, comparing to control animals infected with heat killed C.albicans.	Fold change > 2.	WBPaper00050386:C.albicans_4h_downregulated

0 Expression Patterns

0 GO Annotation

0 Homologues

1 Locations

• Feature . Primary Identifier: WBGene00189970
• Start: 15242774
• End: 15242849
• Strand: -1

0 Ontology Annotations

0 Regulates Expr Cluster

1 Sequence

• Length: 76

1 Sequence Ontology Term