WormMine

WS295

Intermine data mining platform for C. elegans and related nematodes

Phenotype : WBPhenotype:0000124 enzyme activity reduced

Description  Any variation that results in a decrease in the catalytic activity of an enzyme compared to control. Catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein (can include an RNA component).

27 RNAi

WormBase ID
WBRNAi00077725
WBRNAi00077724
WBRNAi00077726
WBRNAi00081450
WBRNAi00007199
WBRNAi00092476
WBRNAi00093459
WBRNAi00069816
WBRNAi00069815
WBRNAi00098445
WBRNAi00098452
WBRNAi00081448
WBRNAi00078158
WBRNAi00081447
WBRNAi00081449
WBRNAi00070929
WBRNAi00112314
WBRNAi00070930
WBRNAi00112313
WBRNAi00069814
WBRNAi00069817
WBRNAi00069818
WBRNAi00103094
WBRNAi00092831
WBRNAi00077070
WBRNAi00078403
WBRNAi00078402

22 RNAi Not Observed

WormBase ID
WBRNAi00069797
WBRNAi00069809
WBRNAi00069795
WBRNAi00069794
WBRNAi00103095
WBRNAi00069796
WBRNAi00069799
WBRNAi00069798
WBRNAi00069801
WBRNAi00069800
WBRNAi00069803
WBRNAi00069802
WBRNAi00069805
WBRNAi00069804
WBRNAi00069807
WBRNAi00069806
WBRNAi00069808
WBRNAi00069811
WBRNAi00069810
WBRNAi00069813
WBRNAi00069812
WBRNAi00069793

3 Children

Identifier Name Description
WBPhenotype:0002213 kinase activity reduced Any variation that results in a decrease in the catalytic phosphorylation activity of a kinase enzyme compared to control. Catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein (can include an RNA component). Kinases are enzymes capable of phosphorylating their respective substrates.
WBPhenotype:0001987 acetylcholinesterase activity variant Any variation in the measured levels of acetylcholinesterase (AChE) activity compared to control animals.
WBPhenotype:0000177 acetylcholinesterase reduced Any variation that results in a decrease of acetylcholine esterase levels, compared to control.

1 Data Sets

Name URL
WormBaseAcedbConverter  

1 Parents

Identifier Name Description
WBPhenotype:0000727 enzyme activity variant Any variation in the function of naturally occurring macromolecular substances known as enzymes compared to control. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein (can include an RNA component).

25 Phenotype Allele

Public Name
qa201
ca11
b405
e1295
ad467
ok480
ok1137
ok1242
g72
p1000
p1152
e1392
pc13
op309
um3
ca101ca102
km25
tm2720
tm2572
tm2862
tm3082
tm4417
ok2042
ok3505
 

1 Phenotype Allele Not Observed

Public Name
ok335

0 Synonyms