WormMine

WS297

Intermine data mining platform for C. elegans and related nematodes

GO Term : GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process GO

Namespace  molecular_function Obsolete  false
Description  Binds to and increases the rate of proteolysis catalyzed by a cysteine-type endopeptidase involved in the apoptotic process.

0 Cross References

1 Data Sets

Name URL
GO Annotation data set  

1 Ontology

Name
GO

3 Ontology Annotations

Annotation Extension Qualifier
  enables
  enables
  enables

23 Parents

Identifier Name Description
GO:0009987 cellular process Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0008150 biological_process A biological process is the execution of a genetically-encoded biological module or program. It consists of all the steps required to achieve the specific biological objective of the module. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence.
GO:0003674 molecular_function A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs.
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0016787 hydrolase activity Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc.
GO:0005488 binding The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule.
GO:0140096 catalytic activity, acting on a protein Catalytic activity that acts to modify a protein.
GO:0005515 protein binding Binding to a protein.
GO:0098772 molecular function regulator activity A molecular function regulator regulates the activity of its target via non-covalent binding that does not result in covalent modification to the target. Examples of molecular function regulators include regulatory subunits of multimeric enzymes and channels. Mechanisms of regulation include allosteric changes in the target and competitive inhibition.
GO:0140677 molecular function activator activity A molecular function regulator that activates or increases the activity of its target via non-covalent binding that does not result in covalent modification to the target.
GO:0019899 enzyme binding Binding to an enzyme, a protein with catalytic activity.
GO:0030234 enzyme regulator activity Binds to and modulates the activity of an enzyme.
GO:0006915 apoptotic process A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died.
GO:0008219 cell death Any biological process that results in permanent cessation of all vital functions of a cell. A cell should be considered dead when any one of the following molecular or morphological criteria is met: (1) the cell has lost the integrity of its plasma membrane; (2) the cell, including its nucleus, has undergone complete fragmentation into discrete bodies (frequently referred to as apoptotic bodies). The cell corpse (or its fragments) may be engulfed by an adjacent cell in vivo, but engulfment of whole cells should not be considered a strict criteria to define cell death as, under some circumstances, live engulfed cells can be released from phagosomes (see PMID:18045538).
GO:0012501 programmed cell death A process which begins when a cell receives an internal or external signal and activates a series of biochemical events (signaling pathway). The process ends with the death of the cell.
GO:0002020 protease binding Binding to a protease or a peptidase.
GO:0008233 peptidase activity Catalysis of the hydrolysis of a peptide bond. A peptide bond is a covalent bond formed when the carbon atom from the carboxyl group of one amino acid shares electrons with the nitrogen atom from the amino group of a second amino acid.
GO:0061134 peptidase regulator activity Binds to and modulates the activity of a peptidase, any enzyme that catalyzes the hydrolysis peptide bonds.
GO:0008047 enzyme activator activity Binds to and increases the activity of an enzyme.
GO:0016505 peptidase activator activity involved in apoptotic process Binds to and increases the activity of a peptidase that is involved in the apoptotic process.
GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process Binds to and increases the rate of proteolysis catalyzed by a cysteine-type endopeptidase involved in the apoptotic process.
GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process Binds to and modulates the activity of a cysteine-type endopeptidase involved in the apoptotic process.
GO:0016504 peptidase activator activity Binds to and increases the activity of a peptidase.

29 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0016505 GO:0008656
is_a GO:0043028 GO:0008656
part of GO:0008219 GO:0008656
is_a GO:0061134 GO:0008656
is_a GO:0016504 GO:0008656
regulates GO:0016787 GO:0008656
part of GO:0006915 GO:0008656
has part GO:0002020 GO:0008656
has part GO:0019899 GO:0008656
regulates GO:0003824 GO:0008656
is_a GO:0098772 GO:0008656
is_a GO:0030234 GO:0008656
has part GO:0003674 GO:0008656
positively regulates GO:0140096 GO:0008656
positively regulates GO:0008233 GO:0008656
positively regulates GO:0003824 GO:0008656
regulates GO:0008233 GO:0008656
has part GO:0005515 GO:0008656
positively regulates GO:0003674 GO:0008656
part of GO:0012501 GO:0008656
regulates GO:0140096 GO:0008656
part of GO:0008150 GO:0008656
positively regulates GO:0016787 GO:0008656
is_a GO:0003674 GO:0008656
is_a GO:0008047 GO:0008656
has part GO:0005488 GO:0008656
regulates GO:0003674 GO:0008656
is_a GO:0140677 GO:0008656
part of GO:0009987 GO:0008656

1 Synonyms

Name Type
caspase activator activity synonym