WormMine: AnatomyTerm WBbt:0004424

• Definition: Quadrant outer labial socket
• Name: OLQsoVL
• Primary Identifier: WBbt:0004424
• Synonym: lineage name: ABalppaaapp

1 Children

Definition	Name	Synonym	Primary Identifier
nucleus of pedigree ABalppaaapp	ABalppaaapp nucleus		WBbt:0002455

1 Expression Clusters

Regulated By Treatment	Description	Algorithm	Primary Identifier
	Single-cell RNA-Seq cell group 82_1 with unidentified tissue expression pattern.	scVI 0.6.0	WBPaper00065841:82_1

22 Expression Patterns

• Primary Identifier: Expr4434
• Pattern: Expressed in socket cells of IL or OLQ. Strongly expressed in OLLL and OLLR neurons.

• Primary Identifier: Expr4439
• Pattern: Expressed in the seam cells at embryo. Expressed in socket cells of IL or OLQ. Expression shown in the intestine, usually stronger in the cells at the terminal regions.

• Primary Identifier: Expr4464
• Pattern: Expressed in the rectal epithelial cells from L1 and maintained through adulthood. Expressed in socket cells of IL or OLQ.

• Primary Identifier: Expr4456
• Pattern: Expressed in the hypodermis from embryo stage through adulthood. Expressed in the rectal epithelial cells from L1 and maintain through adulthood. Expressed in the terminal bulb of the pharynx. Expressed in socket cells of IL or OLQ.

• Primary Identifier: Expr4457
• Pattern: Expressed in socket cells of IL or OLQ.

• Primary Identifier: Expr4453
• Pattern: Expressed in socket cells of IL or OLQ.

• Primary Identifier: Expr4445
• Pattern: Expressed in socket cells of IL or OLQ. Expressed in the PVT cell.

• Primary Identifier: Expr4448
• Pattern: Expressed in the rectal epithelial cells from L1 and maintained through adulthood. Expressed in socket cells of IL or OLQ.

• Primary Identifier: Expr4440
• Pattern: Expressed in socket cells of IL or OLQ. Expressed in neurons of the lumbar ganglion, but the specific neurons were not identified.

• Primary Identifier: Expr4441
• Pattern: Expressed in socket cells of amphids, IL or OLQ.

• Primary Identifier: Marker30
• Remark: Picture: Fig. 1G, 1H, Fig S1G-L.
• Pattern: Expressed in CEPsh glia and in sheath and socket glia of inner and outer labial sensilla, and of the deirid.

• Primary Identifier: Expr11754
• Remark: Isoform 1a

• Primary Identifier: Expr11756
• Remark: Isoform 1b.2

• Primary Identifier: Expr8673
• Remark: Picture: Fig 3.
• Pattern: Expression in the alimentary canal: Strong and consistent expression in anterior arcades, posterior arcades, M1, B cell. Weak or rare expression in intestine. Expression in the nervous system: Amsh, CEPsh, CEPso, ILso, OLso, Phso, DVC, MI. Expression in the reproductive system: In adult stage, expressed in gonad sheath, uterus, vulva(low), spermatheca, Sp-ut valve. In developing larva stage, expressed in uterus, vulva, spermatheca, Sp-ut valve. inx-5 first appears in the developing hypodermis at bean stage and then in the excretory cell at three-fold stage.

• Primary Identifier: Expr8786
• Remark: Picture: Fig 6.
• Pattern: Apart from cells in the neuroblast lineage that generate ASE, nhr-67::mCherry was expressed in multiple other neuroblast lineages in the developing embryo. Expression was usually observed in the grandmother or mother of a neuron, but not earlier. Within the ASEL and ASER-generating lineage branches, nhr-67 was expressed in neuroblasts that generate closely or distantly related cousins of ASEL and ASER. For example, the sister neuroblast of the ASE-generating neuroblast creates the AUA and ASJ neurons and it expressed nhr-67. The cousin of the ASE-mother cell generates the AWB and ADF sensory neurons. nhr-67 was expressed in these cells. In late stage embryos, a few other, postmitotic neurons started to express nhr-67. Embryonic nhr-67 expression was not restricted to the nervous system, but was observed in a small subset of mesodermal and hypodermal cells. No expression was detected in endodermal cells or the germ line. nhr-67 was expressed in the excretory canal cell. Postembryonically, nhr-67 expression persisted only in a few neurons in the head ganglia until the first larval stage and faded shortly thereafter in most, but not all, of these neurons, with expression persisting through adulthood only in the CEPD/V, RMED/V, AVL and RIS neurons. During mid-larval development, nhr-67 was transiently and dynamically expressed in the AC cells of the vulva. Expression was also found in the VU cells and somatic gonad, but not in vulA, vulB or vulC. Within the ASEL/R generating lineages, nhr-67::mCherry was first observed in the grandmother cells of ASEL and ASER. Transgenic animals that co-express a functional nhr-67::mCherry reporter and a functional che-1::yfp reporter revealed that nhr-67 precedes che-1 expression. nhr-67 expression was maintained in the ASEL and ASER neurons until the first larval stage after which it became undetectable, whereas che-1 expression was maintained throughout the life of the animal. In spite of its genetically deduced role in asymmetric gene expression in ASEL and ASER, nhr-67 expression is bilaterally symmetric in ASEL and ASER.

• Primary Identifier: Expr3859
• Pattern: dpy-14 expression starts at the "16 E cell period", a stage when the embryo consists of 224N-500 cells and 4.25N-5.5 h have elapsed since fertilization. As embryogenesis progresses, expression of dpy-14 becomes clearly hypodermal and is mainly localized to hyp7. In addition to embryonic expression, some GFP fluorescence was observed in the hyp7 syncytium of L1 worms, but not at later larval stages or in adults. This L1 expression is probably an artefact due to the relatively long half-life of GFP. GFP expression of dpy-14 at the lima bean stage was mainly localized to cells of AB lineage that may be grouped into two categories based on their potential to differentiate into hypodermal cells only (AB.alaa, AB.alap, AB.arpa, AB.arap, AB.arpp and AB.alpa), or into either hypodermal cells or ciliated neurons (AB.praa, AB.prap, AB.plpp, AB.plpa and AB.alpp). At the plum stage, expression was localized to hyp7 nuclei and to some amphids (ADFL, AFDL, ASEL, ASHL, ASJL, ASKL and RIAL) and amphid support cells (IlshL and OLQsoVL).

• Primary Identifier: Expr8693
• Remark: Picture: N.A.
• Pattern: Expression in the alimentary canal: Weak or rare expression in intestine. Expression in the nervous system: OLso, AVD, AVG, AVJ, AVK, DVA, DVC, IL1, PVP, RIC, RIF, RMD, SIB, SMD, URA.

• Primary Identifier: Expr8680
• Remark: Picture: N.A.
• Pattern: Expression in the alimentary canal: Strong and consistent expression in M2, rectal epithelial cells. Weak or rare expression in anterior arcades, posterior arcades. Expression in the nervous system: Amsh, CEPso, ILso, OLso, PDEso, AVH (early larva), AVJ (early larva), AVK, CAN, IL1 (early larva), PDE, PVD, SIB (early larva), URB, VAn, VBn, M2. Expression in the reproductive system: In adult stage, expressed in vulva, spermatheca, sperm(spermatocytes, spermatids). In developing larva stage, expressed in vulva. inx-12 expressionstarts in seam precursors around 1.5-fold stage, followed by expression in arcade cells by 2-fold and head neurons by 3-fold stage. inx-12 is expressed in the hypodermal cells of the animal in postembryonic stages.

• Primary Identifier: Expr8930
• Remark: Picture: N.A.
• Pattern: Expressed in all intestinal cells(weak), major hypodermis, vulva epithelium, rectal epithelium, AMsh, IL/OLso and excretory duct cell.

• Primary Identifier: Expr8681
• Remark: Picture: N.A.
• Pattern: Arcade cells are seen to express inx-13 at high levels starting around two-fold stage continuing throughout development and adulthood. inx-13 is expressed in the hypodermal cells of the animal in postembryonic stages. Expression in the alimentary canal: Strong and consistent expression in M1, M2. Weak or rare expression in intestine, rectal epithelial cells. Expression in the nervous system: Amsh, CEPsh, CEPso, ILsh, ILso, OLsh, OLso, Phsh, CAN, DVA, DVB, DVC, LUA, PHA, PHB, PLN, PVC, PVQ, PVR, M1, M2. Expression in the reproductive system: In adult stage, expressed in spermatheca, sp-ut valve.

• Primary Identifier: Expr3225
• Remark: Reporter gene fusion type not specified.
• Pattern: LEV-8 is first detected in L1 animals in a single pair of neurons in the head, approximately midway along the isthmus. It is also expressed in the PVT interneuron situated in the lumbar ganglion, at the rear of the animal. By L4, LEV-8 is expressed in all six DD motor neurons in the ventral nerve cord. As well as expression in several neuronal cell types, LEV-8 is expressed in body wall and in uterine muscles UV1 and UV2. Expression in the body wall was strongest anteriorly, which accords with the higher level of resistance exhibited by the head muscles of lev-8(x15) mutant worms. In the adult worm, LEV-8 is expressed in many neurons in the anterior nervous system. One of the more prominent of these is a single cell in the dorsal ganglion, ALA. LEV-8 is expressed in the IL and OL socket cells but not the neurons themselves.

• Primary Identifier: Expr9160
• Remark: Picture: Fig. 3.
• Pattern: Expression of itx-1prom::gfp was observed in the intestinal tract of embryos from 1.5-fold stage throughout post-embryonic larval development and adulthood. Furthermore, GFP could be detected in socket cells ensheathing the inner and outer labial neurons. Expression could also be observed in the spermatheca and vulva muscle cells. No other cell type displays consistent reporter gene expression.

11 Life Stages

Remark	Definition	Other Name	Public Name	Primary Identifier
	The whole period of embryogenesis in the nematode Caenorhabditis elegans, from the formation of an egg until hatching.		embryo Ce	WBls:0000003
	The C. elegans life stage spanning 620-800min(hatch) after first cleavage at 20 Centigrade. Cell number remains at ~560 cells, with some new cells generated and some cells go through programmed cell death. A stage after elongation is over. The last stage of embryogenesis. Also called pre-hatched embryo, late embryo or morphogenetic embryo.		fully-elongated embryo Ce	WBls:0000021
	The C. elegans life stage spanning 350-620min after first cleavage at 20 Centigrade. Cell number remains at ~560 cells, with some new cells generated and some cells go through programmed cell death. The stage that embryo starts elongation until elongation is over.		elongating embryo Ce	WBls:0000015
	The C. elegans life stage spanning 290-350min after first cleavage at 20 Centigrade. Proliferate from 421 cells to 560 cells. The stage when embryo just finished gastrulation and is enclosing.		enclosing embryo Ce	WBls:0000013
	The C. elegans life stage spanning 0-350min after first cleavage at 20 Centigrade. Proliferate from 1 cell to 560 cells. From start of first cleavage until cleavage is over.		proliferating embryo Ce	WBls:0000004
	The C. elegans life stage spanning 390-420min after first cleavage at 20 Centigrade. Cell number remains at ~560 cells, with some new cells generated and some cells go through programmed cell death. The shape of embryo looks like a comma. A stage between bean embryo and 1.5-fold embryo.		comma embryo Ce	WBls:0000017
	The C. elegans life stage spanning 460-520min after first cleavage at 20 Centigrade. Cell number remains at ~560 cells, with some new cells generated and some cells go through programmed cell death. The shape of embryo is elongated and double fold. A stage between 1.5-fold embryo and 3-fold embryo.		2-fold embryo Ce	WBls:0000019
	The C. elegans life stage spanning 520-620min after first cleavage at 20 Centigrade. Cell number remains at ~560 cells, with some new cells generated and some cells go through programmed cell death. The shape of embryo is elongated and tripple fold. A stage between 2-fold embryo and fully-elongated embryo. Also called pretzel embryo or pretzel stage.		3-fold embryo Ce	WBls:0000020
	The C. elegans life stage spanning 420-460min after first cleavage at 20 Centigrade. Cell number remains at ~560 cells, with some new cells generated and some cells go through programmed cell death. The shape of embryo is elongated and fold back 50%. A stage between comma embryo and 2-fold embryo.		1.5-fold embryo Ce	WBls:0000018
	The C. elegans life stage spanning 350-390min after first cleavage at 20 Centigrade. Cell number remains at ~560 cells, with some new cells generated and some cells go through programmed cell death. Emrbyo elongation started but have not formed comma shape yet. The shape of embryo looks like a lima bean. A stage right before comma embryo. Also called lima embryo or lima bean stage.		bean embryo Ce	WBls:0000016
	The C. elegans life stage spanning 210-350min after first cleavage at 20 Centigrade. Proliferate from 421 cells to 560 cells. The stage before the fast cleavage of cells finishes.		late cleavage stage embryo Ce	WBls:0000014

4 Parents

Definition	Name	Synonym	Primary Identifier
outer labial socket cell.	OL socket cell		WBbt:0008419
embryonic cell	ABalppaaap		WBbt:0006332
	OL quadrant ventral left sensillum		WBbt:0005506
portion of anterior ganglion of somatic nervous system that is anterior to the metacorpus of pharynx.	anterior ganglion (ant)		WBbt:0005372