WormMine: ExpressionPattern Expr694

• Pattern: Expression observed in cells of Q lineage, at first expression is specific for the left Q cell lineage; No expression in QR or its descendants. mab-5::lacZ is not expressed in QL during initial mab-5 independent phase of its migration but is switched on in QL during the course of its migration. beta-galactosidase expression is strongest after first division and persists throughout the migration of the QL descendants. QL moves into a region of the body where ectodermal, mesodermal and endodermal cells express mab-5-lacZ, QR migrates anteriorly into a region where only the juvenile neurons express mab-5-lacZ. After Q cell migration is complete expression observed in QL at low-level but not in QR. After Q cells have divided, QL descendants express high levels of the fusion. Staining persists in all QL descendants throughout migration and to end of L1. There is no expression in QR descendants. 0-2 hours after hatching No expression in Q cell. 2-3h expression observed in QL cells migrating up over V5. Expression observed in all posterior cells in which mab-5 function is predicted genetically, as well as the posterior intestine and juvenile neurons.
• Primary Identifier: Expr694
• Remark: LacZ expression in posterior of the worm-consistent with in situ pattern. This information was extracted from published material (Archana Sharma-Oates, Andrew Mounsey and Ian A. Hope).

8 Anatomy Terms

Definition	Name	Synonym	Primary Identifier
A chain of very large cuboidal cells forming a wide central lumen in which food arrives from the posterior pharynx, is digested, and from which waste products proceed to the rectum. Intestinal rings form in groups of two and four cells surrounding the common lumen; thus the epithelium is only one cell deep at any point, with neighboring cells firmly secured to their neighbors by apical adherens junctions. These cells have very large nuclei and many large vacuoles, yolk granules, and other inclusions; the latter increase in number and electron density as the animal ages.	intestine	gut	WBbt:0005772
Major cell type of nervous tissue, specialized for transmission of information in the form of patterns of impulses.	neuron	neurone	WBbt:0003679
Postembryonic neuroblast, migrates posteriorly.	QL	lineage name: ABplapapaaa	WBbt:0004056
post-embryonic cell of pedigree QL.a	QL.a		WBbt:0007274
post-embryonic cell of pedigree QL.pp	QL.pp		WBbt:0007278
post-embryonic cell of pedigree QL.pa	QL.pa		WBbt:0007277
post-embryonic cell of pedigree QL.p	QL.p		WBbt:0007276
post-embryonic cell of pedigree QL.aa	QL.aa		WBbt:0007275

1 Genes

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00003102	mab-5	C08C3.3	Caenorhabditis elegans

2 Life Stages

Remark	Definition	Other Name	Public Name	Primary Identifier
	The first stage larva. At 25 Centigrade, it ranges 14-25.5 hours after fertilization, 0-11.5 hours after hatch.		L1 larva Ce	WBls:0000024
	The whole period of embryogenesis in the nematode Caenorhabditis elegans, from the formation of an egg until hatching.		embryo Ce	WBls:0000003