WormMine: ExpressionPattern Expr1060

• Pattern: RIC-8 immunoreactivity observed throughout the nervous system in both juvenile and adult worms. In juveniles, but not adults, however, immunoreactivity was observed around the nuclei of many nonneuronal cells, including germ cell nuclei. Both neuronal and nonneuronal RIC-8 staining were absent in animals stained with a RIC-8 preabsorbed antibody preparation. Within the nervous system, RIC-8 appears to be present in most or all neurons, including those comprising the ventral nerve cord, although the amount of staining varied greatly between individual neurons. Observed RIC-8 staining in neuronal processes, including strong staining of amphid dendritic processes and weaker staining at some cholinergic synapses in the ventral nerve cord, as well as the axonal processes of the nerve ring.
• Primary Identifier: Expr1060
• Subcellular Localization: RIC-8 staining in neuronal cell somas did not appear localized but instead appeared to fill the cytoplasm.

2 Anatomy Terms

Definition	Name	Synonym	Primary Identifier
Major cell type of nervous tissue, specialized for transmission of information in the form of patterns of impulses.	neuron	neurone	WBbt:0003679
cell line which early in development becomes differentiated from the remaining somatic cell line, and alone has the potential to undergo meiosis and form gametes.	germ line	germline	WBbt:0005784

1 Genes

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00004367	ric-8	Y69A2AR.2	Caenorhabditis elegans

1 Life Stages

Remark	Definition	Other Name	Public Name	Primary Identifier
	A developemental life stage of the nematode Caenorhabditis elegans that occurs from egg hatching until death.		postembryonic Ce	WBls:0000022