WormMine: ExpressionPattern Expr1360

• Pattern: Both gfp reporter constructs showed identical expression patterns throughout development in the nervous system and in muscle cells. Animals with an integrated gpb-2::gfp array showed no expression in embryos until the comma stage when broad expression was seen, excluding the dorsal posterior site of the comma stage embryo. From the comma stage onward, when tissues differentiate and become organized, until hatching of the embryos, gpb-2 expression was stronger and broadly expressed in the head and tail ganglia. In larvae and adult animals, gpb-2 expression was seen in most or all neurons, including neurons located in the head ganglia, the ventral nerve cord, and the tail ganglia. Additionally, gpb-2 expression was seen in the hermaphrodite-specific neurons (HSNs), which control egg laying and the canal cell-associated neurons (CANs). Besides neuronal expression, high expression levels of gpb-2 were also seen in muscle cells of the pharynx, the vulva muscle cells, and the body-wall muscle cells. In males, similar neuronal and muscle expression was observed. Thus, gpb-2 is widely expressed in most neurons and in muscle cells that control several distinct behaviors.
• Primary Identifier: Expr1360

4 Anatomy Terms

Definition	Name	Synonym	Primary Identifier
type of cells that make up muscle layers in the pharynx.	pharyngeal muscle cell		WBbt:0005451
Longitudinal bands of muscle cells surrounding animal body, with one band running in each quadrant of the body, regulated contraction and relaxation of these muscles cause locomotion.	body wall musculature	body muscle	WBbt:0005813
muscle associated with hermaphrodite vulva.	vulval muscle		WBbt:0005821
Major cell type of nervous tissue, specialized for transmission of information in the form of patterns of impulses.	neuron	neurone	WBbt:0003679

1 Genes

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00001680	gpb-2	F52A8.2	Caenorhabditis elegans

6 Life Stages

Remark	Definition	Other Name	Public Name	Primary Identifier
	The C. elegans life stage spanning 620-800min(hatch) after first cleavage at 20 Centigrade. Cell number remains at ~560 cells, with some new cells generated and some cells go through programmed cell death. A stage after elongation is over. The last stage of embryogenesis. Also called pre-hatched embryo, late embryo or morphogenetic embryo.		fully-elongated embryo Ce	WBls:0000021
	The C. elegans life stage spanning 390-420min after first cleavage at 20 Centigrade. Cell number remains at ~560 cells, with some new cells generated and some cells go through programmed cell death. The shape of embryo looks like a comma. A stage between bean embryo and 1.5-fold embryo.		comma embryo Ce	WBls:0000017
	The C. elegans life stage spanning 460-520min after first cleavage at 20 Centigrade. Cell number remains at ~560 cells, with some new cells generated and some cells go through programmed cell death. The shape of embryo is elongated and double fold. A stage between 1.5-fold embryo and 3-fold embryo.		2-fold embryo Ce	WBls:0000019
	The C. elegans life stage spanning 520-620min after first cleavage at 20 Centigrade. Cell number remains at ~560 cells, with some new cells generated and some cells go through programmed cell death. The shape of embryo is elongated and tripple fold. A stage between 2-fold embryo and fully-elongated embryo. Also called pretzel embryo or pretzel stage.		3-fold embryo Ce	WBls:0000020
	The C. elegans life stage spanning 420-460min after first cleavage at 20 Centigrade. Cell number remains at ~560 cells, with some new cells generated and some cells go through programmed cell death. The shape of embryo is elongated and fold back 50%. A stage between comma embryo and 2-fold embryo.		1.5-fold embryo Ce	WBls:0000018
	A developemental life stage of the nematode Caenorhabditis elegans that occurs from egg hatching until death.		postembryonic Ce	WBls:0000022