WormMine: ExpressionPattern Expr860

• Pattern: CLE-1 strongly accumulates in a punctate pattern associated with the nerve ring and the dorsal and ventral nerve cords. This pattern is first visible at the two-fold stage of embryogenesis (~460 min) and persists in all subsequent stages. Beginning in the L4 larval stage, CLE-1 is also observed in basement membranes surrounding the gonad, pharynx, and intestine, and under body wall muscles where it preferentially accumulates at junctions between muscle cells and along dense body lines. The apparently more limited distribution of CLE-1 in early development may result from low sensitivity of detection with the antibody.
• Primary Identifier: Expr860
• Subcellular Localization: Under body wall muscles where it preferentially accumulates at junctions between muscle cells and along dense body lines

8 Anatomy Terms

Definition	Name	Synonym	Primary Identifier
A chain of very large cuboidal cells forming a wide central lumen in which food arrives from the posterior pharynx, is digested, and from which waste products proceed to the rectum. Intestinal rings form in groups of two and four cells surrounding the common lumen; thus the epithelium is only one cell deep at any point, with neighboring cells firmly secured to their neighbors by apical adherens junctions. These cells have very large nuclei and many large vacuoles, yolk granules, and other inclusions; the latter increase in number and electron density as the animal ages.	intestine	gut	WBbt:0005772
a large process bundle that runs along the vental mid-line extending from the ventral region of the nerve ring.	ventral nerve cord	ventral cord	WBbt:0005829
Longitudinal bands of muscle cells surrounding animal body, with one band running in each quadrant of the body, regulated contraction and relaxation of these muscles cause locomotion.	body wall musculature	body muscle	WBbt:0005813
the feeding organ, a neuro-muscular pump in the head of the animal, used to ingest food, bacteria suspended in liquid, filter them out, grind them up and transport posteriorly into the instestine.	pharynx	esophagus	WBbt:0003681
the most extensive region of neuropil in the animal, consists of a large toroidal bundle of processes.	nerve ring	circumpharyngeal nerve ring	WBbt:0006749
a bundle of nerve processes that runs along the dorsal mid-line of the animal.	dorsal nerve cord	dorsal cord	WBbt:0006750
organ producing either sperm or ova.	gonad		WBbt:0005175
	basal lamina	basement membrane	WBbt:0005756

1 Genes

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00000527	cle-1	C36B1.1	Caenorhabditis elegans

0 Life Stages